A5070876436- Spine and Intervertebral Disc Pathology
- Spinal Dysraphism and Malformations
- Meningioma and schwannoma management
- Long-Term Effects of COVID-19
- Glioma Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Musculoskeletal pain and rehabilitation
- COVID-19 Clinical Research Studies
- Head and Neck Surgical Oncology
- Retinal and Optic Conditions
- Cerebrospinal fluid and hydrocephalus
- Intracranial Aneurysms: Treatment and Complications
- Pelvic floor disorders treatments
- Anesthesia and Pain Management
- Acute Ischemic Stroke Management
- Epilepsy research and treatment
- Urinary Bladder and Prostate Research
- Pituitary Gland Disorders and Treatments
- Pregnancy-related medical research
- Management of metastatic bone disease
- Fetal and Pediatric Neurological Disorders
- Cancer-related cognitive impairment studies
- Cancer, Stress, Anesthesia, and Immune Response
- Chemokine receptors and signaling
Başkent University
2021-2024
Başkent University Hospital
2022-2024
Istanbul University-Cerrahpaşa
2019-2021
Istanbul University
2018-2020
Background and Purpose: Stroke is reported as a consequence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in several reports. However, data are sparse regarding the details these patients multinational large scale. Methods: We conducted observational study on features consecutive ischemic stroke, intracranial hemorrhage, cerebral venous or sinus thrombosis among SARS-CoV-2–infected patients. further investigated risk vessel occlusion, stroke severity measured by...
Preoperative neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte (PLR) and lymphocyte-monocyte (LMR) are recognized as prognostic markers of grade gliomas. The aim this study was to determine whether preoperative levels NLR, PLR, LMR differ between low- high-grade gliomas.Retrospective analysis neutrophil, lymphocyte, monocyte, platelet counts were performed in 171 patients who underwent glioma surgery. results compared gliomas.Neutrophil count significantly increased while lymphocyte...
Abstract Background Stroke is reported as a consequence of SARS-CoV-2 infection. However, there lack regarding comprehensive stroke phenotype and characteristics Methods We conducted multinational observational study on features consecutive acute ischemic (AIS), intracranial hemorrhage (ICH), cerebral venous or sinus thrombosis (CVST) among infected patients. further investigated the association demographics, clinical data, geographical regions, countries’ health expenditure AIS patients...
High-grade gliomas have limited time of survival despite aggressive treatment. Patients experience a decline in their physical and mental capacities, affecting quality life (QoL), require proper therapeutic strategies.To assess the QoL malignant glioma patients before after treatment longitudinal study six months.Forty-nine who were pathologically diagnosed with glioblastoma anaplastic according to WHO 2016 included this prospective study. The assessment was done using European Organization...
AIM:To measure the serum levels of strong angiostatic and synaptogenetic molecules thrombospondin-1 (TSP-1) thrombospondin-2 (TSP-2) in patients with temporal lobe epilepsy (TLE) before after surgery. MATERIAL METHODS:In this prospective study, 20 operated for TLE healthy subjects were included.Serum TSP-1 TSP-2 measured using enzyme-linked immunosorbent assay (ELISA). RESULTS:Our findings showed that both groups had higher "before" surgery than 10 days "after" surgery.However, a significant...
BACKGROUND: Prenatal spina bifida repair and its clinical outcome are increasingly seen as topics of research even though early postnatal is routinely recommended for the treatment bifida. The aim this study was to evaluate cranio-spinal MRI findings in patients following prenatal a five-year follow-up study.METHODS: Hydrocephalus, Chiari malformation, malformations cortical development, vertebral anomalies, syringohydromyelia, diastematomyelia, tethered cord were parameters investigated...
Abstract Background Spina bifida’s prevalence and incidence vary across geographical regions with sociodemographic characteristics socioeconomic status of the populations having a significate influence over its epidemiology. This study aimed to outline profile families spina bifida children, based on characteristics. Methods Between August December 2022, 86 surveys completed by parents children that underwent repair in our institution were included this analysis. The first part survey...
The aim of this study is to assess associated cerebral supratentorial anomalies in patients who underwent myelomeningocele repair hopes developing a better morphological apprehension the forebrain's category patients. This retrospective observational assessed 426 pediatric between January 2013 and December 2020. Cranial MRIs with T1- T2-weighted sequences were obtained as part postoperative assessment determine presence following repair. most common identified are configuration corpus...
Introduction. Seizure following meningioma surgery is common and management may be challenging. Identifying risk factors help physicians to initiate optimal medical management. The aim of this study report seizure outcome for perioperative seizure.
 Materials Methods. Sixty-three adult patients who underwent supratentorial resection were included, data long-term follow-up provided in retrospective study. Binary logistic regression analysis was used identify the postoperative late...
To retrospectively analyze the results obtained from posterior-only approach in non-pathological traumatic thoracolumbar body fractures with spinal cord compression.A total of 17 patients were included study. Demographic details include preoperative data such as neurological status, deformity, pain scores, and radiology; intraoperative blood loss, duration surgery, complications, postoperative including neurologic status; hospital stay, deformity correction analyzed.Among patients, 8 ASIA A,...
To elucidate the role of TIR-domain-containing adaptor-inducing interferon-? (TRIF) dependent pathway in intervertebral disc degeneration (IVD).A total adult male patients with low back pain (LBP) (+/- radicular pain) were further evaluated by magnetic resonance imaging (MRI) surgical indication for microscopic lumbar herniation (LDH). Preoperatively, classified according to Modic Changes (MC), nonsteroidal anti-inflammatory drugs (NSAIDs) use, and presence addition LBP.The age 88 ranged...
To define the substantial role of TLR4 signaling pathway in MyD88-dependent pathway, and to evaluate results activation nucleus pulposus cells. Moreover, we aim associate this with intervertebral disc degeneration magnetic resonance imaging (MRI) findings. Additionally, clinical differences among patients effects their drug use will be evaluated.Eighty-eight adult male lower back pain sciatica underwent MRI studies, which showed degenerative changes. Disc materials were obtained...
Abstract Background Cavernomas are usually found in the supratentorial area, and epileptic seizures one of presenting symptoms. Objective This study aims to provide seizure outcome adult patients who underwent surgical excision single cavernomas. Materials Methods A total 23 with cavernomas were operated between May 2011 January 2019. Pre- postoperative semiology, clinical, radiological findings collected from medical records. At last follow-up, each patient was seen during regular visits...