Yannan Zhao

ORCID: 0000-0003-0945-2540
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Research Areas
  • Advanced Nanomaterials in Catalysis
  • Advanced biosensing and bioanalysis techniques
  • Antimicrobial agents and applications
  • Nanocluster Synthesis and Applications
  • Synthesis and bioactivity of alkaloids
  • Infective Endocarditis Diagnosis and Management
  • Pharmacological Effects and Toxicity Studies
  • X-ray Diffraction in Crystallography
  • Plant-based Medicinal Research
  • Crystallization and Solubility Studies
  • Carbon and Quantum Dots Applications
  • Orthopedic Infections and Treatments
  • Nanoplatforms for cancer theranostics
  • Pharmacological Effects of Natural Compounds
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Cancer therapeutics and mechanisms
  • Synthesis and pharmacology of benzodiazepine derivatives
  • Antimicrobial Peptides and Activities
  • Bacterial Identification and Susceptibility Testing
  • Traditional Chinese Medicine Analysis

Xi'an Honghui Hospital
2025

Xi'an Jiaotong University
2025

Chongqing Medical University
2019-2021

Chongqing Medical and Pharmaceutical College
2020

Bohai University
2016

Drug-resistant pathogenic bacteria as a worldwide health threat calls for valid antimicrobial agents and tactics in clinical practice. Positively charged materials usually achieve antibacteria through binding disrupting bacterial membranes via electrostatic interaction, however, they also cause hemolysis cytotoxicity. Herein, we engineered negatively sulfur quantum dots (SQDs) an efficient broad-spectrum antibiotic to kill drug-resistant vitro vivo. The SQDs can destroy the membrane system...

10.1021/acs.nanolett.1c02697 article EN Nano Letters 2021-11-09

Orthopedic wound infection is a difficult problem in the clinic. Accurate and rapid microbiological test results are essential for case management, antibiotic therapy, control. We retrospectively evaluated 1285 specimens (puncture fluid, catheter, secretions, joint lavage extraction blood culture, drainage cerebrospinal bone, prosthesis tissue, etc.) from 739 patients who received orthopedic diagnosis treatment, using routine conventional method (RCM)s as reference to evaluate performance of...

10.1186/s12879-025-10847-0 article EN cc-by-nc-nd BMC Infectious Diseases 2025-04-01

The overuse of antibiotics has contributed to the emergence multidrug-resistant bacteria, which poses a challenging task for clinical therapy. Thus, new agents with antibiotic efficacy against infections are needed. traditional Dong ethnic minority medicines have emerged as source prodrug selection. Among them, Madeng'ai (PotentillafreynianaBornm) is widely used by folk anti-infection and wound healing, although mechanisms remain unclear. In this study, antimicrobial activities medicine were...

10.1155/2022/3678240 article EN Evidence-based Complementary and Alternative Medicine 2022-08-01

Abstract Background Due to the overuse of antibiotics, many multidrug-resistant bacteria have emerged, which brings huge challenges clinical treatment bacterial infections. New products for anti-infection are necessary. Methods Madeng’ai powder was added with Milli-Q water or LB culture and autoclaved prepare medicine suspension at different concentration. Bacteria were cultured in concentration Madeng’ai. swab on agar plates get minimal inhibitory (MIC) Mice back cut make wound MRSA/PAE...

10.21203/rs.3.rs-181332/v1 preprint EN cc-by Research Square (Research Square) 2021-02-15
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