- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Antimicrobial agents and applications
- Nanocluster Synthesis and Applications
- Synthesis and bioactivity of alkaloids
- Infective Endocarditis Diagnosis and Management
- Pharmacological Effects and Toxicity Studies
- X-ray Diffraction in Crystallography
- Plant-based Medicinal Research
- Crystallization and Solubility Studies
- Carbon and Quantum Dots Applications
- Orthopedic Infections and Treatments
- Nanoplatforms for cancer theranostics
- Pharmacological Effects of Natural Compounds
- Phenothiazines and Benzothiazines Synthesis and Activities
- Cancer therapeutics and mechanisms
- Synthesis and pharmacology of benzodiazepine derivatives
- Antimicrobial Peptides and Activities
- Bacterial Identification and Susceptibility Testing
- Traditional Chinese Medicine Analysis
Xi'an Honghui Hospital
2025
Xi'an Jiaotong University
2025
Chongqing Medical University
2019-2021
Chongqing Medical and Pharmaceutical College
2020
Bohai University
2016
Drug-resistant pathogenic bacteria as a worldwide health threat calls for valid antimicrobial agents and tactics in clinical practice. Positively charged materials usually achieve antibacteria through binding disrupting bacterial membranes via electrostatic interaction, however, they also cause hemolysis cytotoxicity. Herein, we engineered negatively sulfur quantum dots (SQDs) an efficient broad-spectrum antibiotic to kill drug-resistant vitro vivo. The SQDs can destroy the membrane system...
Orthopedic wound infection is a difficult problem in the clinic. Accurate and rapid microbiological test results are essential for case management, antibiotic therapy, control. We retrospectively evaluated 1285 specimens (puncture fluid, catheter, secretions, joint lavage extraction blood culture, drainage cerebrospinal bone, prosthesis tissue, etc.) from 739 patients who received orthopedic diagnosis treatment, using routine conventional method (RCM)s as reference to evaluate performance of...
The overuse of antibiotics has contributed to the emergence multidrug-resistant bacteria, which poses a challenging task for clinical therapy. Thus, new agents with antibiotic efficacy against infections are needed. traditional Dong ethnic minority medicines have emerged as source prodrug selection. Among them, Madeng'ai (PotentillafreynianaBornm) is widely used by folk anti-infection and wound healing, although mechanisms remain unclear. In this study, antimicrobial activities medicine were...
Abstract Background Due to the overuse of antibiotics, many multidrug-resistant bacteria have emerged, which brings huge challenges clinical treatment bacterial infections. New products for anti-infection are necessary. Methods Madeng’ai powder was added with Milli-Q water or LB culture and autoclaved prepare medicine suspension at different concentration. Bacteria were cultured in concentration Madeng’ai. swab on agar plates get minimal inhibitory (MIC) Mice back cut make wound MRSA/PAE...