- Photodynamic Therapy Research Studies
- Reproductive biology and impacts on aquatic species
- Nanoplatforms for cancer theranostics
- Microbial infections and disease research
- Molecular Biology Techniques and Applications
- Cancer, Hypoxia, and Metabolism
- Aquaculture disease management and microbiota
- Corneal Surgery and Treatments
- Photoacoustic and Ultrasonic Imaging
- Ecology and Conservation Studies
- Sperm and Testicular Function
- Reproductive Biology and Fertility
Institute of Animal Biochemistry and Genetics of the Slovak Academy of Sciences
2021-2023
Slovak Academy of Sciences
2022-2023
Centre of Biosciences of the Slovak Academy of Sciences
2022
Aspects related to the response of cells photodynamic therapy (PDT) have been well studied in cell cultures, which often grow monolayers. In this work, we propose a spheroidal model U87MG and SKBR3 designed mimic superficial tumor tissue, small spheroids (<500 µm) suitable for confocal fluorescence microscopy, larger (>500 that can be xenografted onto quail chorioallantoic membrane (CAM) study effects PDT real time. Hypericin was used as molecule hydrophobic photosensitizer produce singlet...
The chorioallantoic membrane (CAM) of an avian embryo is a thin, extraembryonic that functions as primary respiratory organ. Its properties make it excellent in vivo experimental model to study angiogenesis, tumor growth, drug delivery systems, or photodynamic diagnosis (PDD) and therapy (PDT). At the same time, this addresses requirement for replacement animals with suitable alternative. Ex ovo cultivated allows easy substance application, access, monitoring, documentation. most frequently...
The chorioallantoic membrane (CAM) of an avian embryo is a thin, extraembryonic that functions as primary respiratory organ. Its properties make it excellent in vivo experimental model to study angiogenesis, tumor growth, drug delivery systems, or photodynamic diagnosis (PDD) and therapy (PDT). At the same time, this addresses requirement for replacement animals with suitable alternative. Ex ovo cultivated allows easy substance application, access, monitoring, documentation. most frequently...