A5043563539- Skin Protection and Aging
- Bee Products Chemical Analysis
- Silymarin and Mushroom Poisoning
- Phytochemicals and Antioxidant Activities
- Genomics, phytochemicals, and oxidative stress
- Free Radicals and Antioxidants
- Dialysis and Renal Disease Management
- Liver Disease and Transplantation
- Antioxidant Activity and Oxidative Stress
- Metabolomics and Mass Spectrometry Studies
- Electrochemical sensors and biosensors
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Pharmacogenetics and Drug Metabolism
- Renal Transplantation Outcomes and Treatments
- melanin and skin pigmentation
- Hormonal and reproductive studies
- bioluminescence and chemiluminescence research
- Berberine and alkaloids research
- Cholinesterase and Neurodegenerative Diseases
- Biochemical effects in animals
- Mass Spectrometry Techniques and Applications
- Advanced Chemical Sensor Technologies
- Drug-Induced Hepatotoxicity and Protection
- Bladder and Urothelial Cancer Treatments
Palacký University Olomouc
2015-2024
University Hospital Olomouc
2014
University of Mons
2008
Université de Limoges
2008
Czech Academy of Sciences, Institute of Microbiology
2008
Flavonolignans from silymarin, the standardized plant extract obtained thistle, exhibit various antioxidant activities, which correlate with other biological and therapeutic properties of that extract. To highlight mode action flavonolignans as free radical scavengers antioxidants, 10 flavonolignans, selectively methylated at different positions, were tested in vitro for their capacity to scavenge radicals (DPPH superoxide) inhibit lipid peroxidation induced on microsome membranes. The...
Most research on American cranberry in the prevention of urinary tract infection (UTI) has used juices. The spectrum components juice is limited. This study tested whether whole fruit powder (proanthocyanidin content 0.56%) could prevent recurrent UTI 182 women with two or more episodes last year. Participants were randomized to a (n = 89) placebo group 93) and received daily 500 mg for 6 months. number diagnoses was counted. intent-to-treat analyses showed that group, UTIs significantly...
Aging is a complex physiological process that can be accelerated by chemical (high blood glucose levels) or physical (solar exposure) factors. It accompanied the accumulation of altered molecules in human body. The oxidatively modified and glycated proteins associated with inflammation progression chronic diseases (aging). use antiglycating agents one recent approaches preventive strategy aging natural compounds seem to promising candidates. Our study focused on anti-aging effect flavonoid...
This study assessed the effect of an 8 week consumption dried cranberry juice (DCJ) on 65 healthy young women. Basic biochemical and hematological parameters, antioxidant status, presence metabolites in urine, urine ex vivo antiadherence activity were determined throughout trial. A 400 mg amount DCJ/day had no influence any parameter tested. 1200 resulted a statistically significant decrease serum levels advanced oxidation protein products. specific protective against oxidative damage...
The ultraviolet (UV) region of solar radiation is a critical factor in the initiation and development number skin diseases. However, it not only which directly exposed to light that affected by UV radiation, through low molecular weight mediators, generated upon irradiation, "non-skin" tissues can also be affected. aim this study was examine detail, acute effects UVA UVB wavebands on hairless mice. Female SKH-1 mice were single dose (200, 800 mJ/cm(2)) or (10, 20 J/cm(2)) using simulator....
Silybum marianum (L.) is a medicinal plant traditionally used in treatment of liver disorders. In last decades, silymarin (SM), standardized extract from S. seeds has been studied for its dermatological application, namely UVB-protective properties. However, information on SM and polyphenols effect activity enzymes participating the (photo)aging process limited. Therefore, evaluation flavonolignans potential to inhibit collagenase, elastase, hyaluronidase tube tests was goal this study. The...
Lower urinary tract symptoms (LUTS) are a common condition in older men. The objective of the present study was to evaluate efficacy and tolerability cranberry ( Vaccinium macrocarpon ) powder men at risk prostate disease with LUTS, elevated prostate-specific antigen (PSA), negative biopsy clinically confirmed chronic non-bacterial prostatitis. Forty-two participants received either 1500 mg dried powdered cranberries per d for 6 months (cranberry group; n 21) or no treatment (control 21)....