A5057515511- Parasite Biology and Host Interactions
- Fish Biology and Ecology Studies
- Reproductive Physiology in Livestock
- Reproductive System and Pregnancy
- Reproductive Biology and Fertility
- Aquatic Invertebrate Ecology and Behavior
- T-cell and B-cell Immunology
- Monoclonal and Polyclonal Antibodies Research
- Endometriosis Research and Treatment
- Helminth infection and control
- Bird parasitology and diseases
- Toxin Mechanisms and Immunotoxins
- Identification and Quantification in Food
- Immune Cell Function and Interaction
- Myxozoan Parasites in Aquatic Species
- Estrogen and related hormone effects
- Aquaculture disease management and microbiota
- Photochemistry and Electron Transfer Studies
- Animal Nutrition and Physiology
- Pluripotent Stem Cells Research
- Tissue Engineering and Regenerative Medicine
- Spectroscopy and Quantum Chemical Studies
- Immune Response and Inflammation
- Veterinary Equine Medical Research
- Malaria Research and Control
Polish Academy of Sciences
2013-2023
Institute of Animal Reproduction and Food Research
2013-2023
Islamic Azad University, Science and Research Branch
2006-2011
Islamic Azad University, Tehran
2009
Boston Biomedical Research Institute
2005-2008
Jamia Millia Islamia
2003-2006
University of Tehran
2006
Hungarian Academy of Sciences
1992
Contents Establishment of pregnancy in pigs requires continuous function corpora lutea and endometrial preparation for embryo implantation. Progesterone regulates expression many proteins necessary remodelling embryo–maternal communications. Attaining the uterine receptivity involves progesterone priming loss receptors epithelium before days 10–12 after oestrus. Spermatozoa oocytes oviduct alter secretion specific that exert beneficial effect on gametes embryos. Moreover, an appropriate...
Viral mutational escape can reduce or abrogate recognition by the T cell receptor (TCR) of virus-specific CD8+ cells. However, very little is known about impact cytotoxic lymphocyte (CTL) epitope mutations on interactions between peptide–major histocompatibility complex (MHC) class I complexes and MHC receptors expressed other types. Here, we analyzed a variant immunodominant human leukocyte antigen (HLA)-B2705–restricted HIV-1 Gag KK10 (KRWIILGLNK) with an L to M amino acid substitution at...
Although cellular processes depend on protein-protein interactions, our understanding of molecular recognition between proteins remains far from comprehensive. Protein-protein interfaces are structural and energetic mosaics in which a subset interfacial residues, called hot spots, contributes disproportionately to the affinity complex. These hot-spot residues can be further clustered into regions. It has been proposed that binding energetics within region cooperative, whereas those regions...
In the current study, transcriptome profiles of mare endometrium, classified into categories I, IIA, and IIB according to Kenney Doig, were compared using RNA sequencing, analyzed, functionally annotated in silico analysis. mild stage (IIA) endometrosis category I differentially expressed genes (DEGs) inflammation, abnormal metabolism, wound healing, quantity connective tissue. moderate (IIB) DEGs fibrosis, cellular homeostasis, mitochondrial dysfunction, pregnancy disorders. Ingenuity...
The denaturation of bovine and horse cytochromes-c by weak salt denaturants (LiCl CaCl2) was measured at 25 °C observing changes in molar absorbance 400 nm (Δε400) circular dichroism (CD) 222 409 nm. Measurements Δε400 mean residue ellipticity ([θ]409) gave a biphasic transition for both modes cytochromes-c. It has been observed that the first phase, N (native) conformation ↔ X (intermediate) second D (denatured) are reversible. Conformational characterization state far-UV CD,...
We have carried out denaturation studies of bovine cytochrome c (cyt c) by LiClO4 at pH 6.0 and 25 °C observing changes in difference molar absorbance 400 nm (Δε400), mean residue ellipticities 222 ([θ]222) ellipticity 409 (Δ[θ]409). The is a three-step process when measured Δε400 Δ[θ]409, it two-step monitored [θ]222. stable folding intermediate state has been characterized near- far-UV circular dichroism, tryptophan fluorescence, 8-anilino-1-naphthalene sulfonic acid (ANS) binding,...
Summary In the present study, we reported infection with eighteen species of genus Dactylogyrus, belong to family Dactylogyridae from five breeder fish species, including common carp (Cyprinus carpio), grass (Ctenopharyngodon idella), silver (Hypophthalmichthys molitrix), big head nobilis) and black (Myelopharyngodon piceus) which introduced imported Iranian freshwaters Russia, Romania, Hungary China over last 40 years. The was also found in Carassius auratus gibelio, it is not known when...
Conceptus attachment is a time-sensitive process that requires synchronized uterine environment created by molecular changes in the endometrium response to ovarian hormones and conceptus signals. Porcine conceptuses undergo rapid elongation differentiation, secrete estrogens serve as maternal-recognition-of-pregnancy signals during peri-implantation period (Days 11–12). Pregnancy-induced proteomic porcine were measured this using two-dimensional differential gel electrophoresis of...
SUMMARY Infusion of seminal plasma in the uterus is known to elicit an instant inflammatory response porcine uterus, but whether or not it prepares a uterine immunological presence conceptuses well understood. Seminal induced long‐term modulatory effects and conceptus‐induced immune changes leukocyte populations were measured by flow cytometry mRNAs for various cytokines quantitative reverse‐transcriptase PCR endometrium collected on Days 6 13 from cycling pregnant animals given infusions....
Abstract Superantigens activate large fractions of T cells through unconventional interactions with both TCR β-chain V domains (Vβs) and MHC class II molecules. The bacterial superantigen streptococcal pyrogenic exotoxin C (SpeC) primarily stimulates human Vβ2+ cells. Herein, we have analyzed the SpeC-Vβ2.1 interaction by mutating all SpeC residues that make contact Vβ2.1 determined energetic functional consequences these mutations. Our comprehensive approach, including mutagenesis, readouts...
Staphylococcus aureus secretes various toxins that act as superantigens by stimulating a large fraction of the host's T cells. Toxin binding to variable domains cell receptor beta chains (Vbeta) leads massive release inflammatory molecules and potentially toxic shock syndrome (TSS). Previously, we generated soluble forms different Vbeta with high affinity for superantigens. However, broader spectrum antagonist is required neutralization multiple toxins. In present study, expressed in tandem...