A5007129180- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
- LGBTQ Health, Identity, and Policy
- Streptococcal Infections and Treatments
- Diabetes Management and Research
- Antimicrobial Resistance in Staphylococcus
- Diabetes Treatment and Management
- Healthcare Policy and Management
- Helicobacter pylori-related gastroenterology studies
- Workplace Health and Well-being
- Diabetes and associated disorders
- Vaccine Coverage and Hesitancy
- Pneumonia and Respiratory Infections
- Sex and Gender in Healthcare
- Antibiotic Use and Resistance
- Employment and Welfare Studies
- Infections and bacterial resistance
- Estrogen and related hormone effects
- Respiratory viral infections research
- Pancreatic function and diabetes
- Food Security and Health in Diverse Populations
- Male Breast Health Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Healthcare Systems and Public Health
The University of Texas at Austin
2022-2024
Austin College
2020-2024
The University of Texas at San Antonio
2022-2024
The University of Texas Health Science Center at San Antonio
2022-2024
South Texas Veterans Health Care System
2024
The University of Texas Health Science Center at Houston
2023
Among carbapenem-resistant Enterobacterales (CRE) are diverse mechanisms, including those that resistant to meropenem but susceptible ertapenem, adding further complexity the clinical landscape. This study investigates emergence of ertapenem-resistant, meropenem-susceptible (ErMs) Escherichia coli and Klebsiella pneumoniae CRE across five hospitals in San Antonio, Texas, USA, from 2012 2018. The majority isolates were non-carbapenemase producers (NCP; 54%; 41/76); 56% all NCP had an ErMs...
This study investigates the emergence of ertapenem-resistant, meropenem-susceptible (ErMs) among non-carbapenemase producing (NCP) and carbapenemase (CP) Escherichia coli Klebsiella pneumoniae. As mutations for ertapenem resistance establish genetic background meropenem resistance, there is a great need antibiotic stewards researchers to understand determinants strain’s propensity become resistant. Whole genome sequencing was conducted on clinical carbapenem-resistant E. (CREC) K. pneumoniae...
Delays in appropriate antibiotic therapy are a key determinant for deleterious outcomes among patients with vancomycin-resistant Enterococcus (VRE) bloodstream infections (BSIs). This was multi-center pre/post-implementation study, assessing the impact of molecular rapid diagnostic test (Verigene® GP-BC, Luminex Corporation, Northbrook, IL, USA) on adult VRE BSIs. The primary outcome time to optimal (TOT). Multivariable logistic and Cox proportional hazard regression models were used...
Metformin may potentially reverse various age-related conditions; however, it is unclear whether metformin can also mitigate or delay the deterioration of immunological resilience that occurs in context infections are commonly observed older persons. We examined promotes preservation an acute S. pneumoniae (SPN) infection challenge young adult mice. Mice were fed (MET-alone) standard chow (controls-alone) for 10 weeks prior to receiving intratracheal inoculation SPN. A subset each diet group...
OBJECTIVES/GOALS: In this study, we aim to report the role of porins and bla CTX-M β-lactamases among Escherichia coli Klebsiella pneumoniae, focusing on emerging carbapenem resistant Enterobacterales (CRE) subtypes, including non-carbapenemase producing (NCPE) ertapenem-resistant but meropenem-susceptible (ErMs) strains. METHODS/STUDY POPULATION: Whole genome sequencing was conducted 76 carbapenem-resistant isolates across 5 hospitals in San Antonio, U.S. Among these, NCP accounted for...
Abstract Background Vancomycin-resistant Enterococcus (VRE) bloodstream infections (BSIs) are associated with high morbidity and mortality. PCR-based rapid diagnostic tests provide prompt identification of infectious etiologies within hours. This study evaluated the impact Verigene® Gram-positive blood culture (GP-BC) panel on outcomes patients VRE BSIs. Methods A multi-center pre- post-implementation retrospective cohort was conducted at four large HCA Healthcare facilities. The...
To survey perceptions and knowledge of transgender/gender-diverse (TGD) healthcare amongst first- through fourth-year (P1-P4) pharmacy students.
Abstract Background Carbapenem-resistant Enterobacterales are a growing threat globally. Early detection of CRE is necessary for appropriate treatment and infection control measures. Many hospital labs can test carbapenemase production; however, in some regions, including South Texas, the majority non-carbapenemase producing (NCPE). This study had two interrelated aims to develop decision rules tailored region with high prevalence NCPE predict 1) antimicrobial resistance (AMR) from whole...