A5008387662- Anesthesia and Pain Management
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Cardiac Ischemia and Reperfusion
- Nausea and vomiting management
- Cardiac, Anesthesia and Surgical Outcomes
- Acupuncture Treatment Research Studies
- Sphingolipid Metabolism and Signaling
- Traumatic Brain Injury and Neurovascular Disturbances
- Mitochondrial Function and Pathology
- Respiratory Support and Mechanisms
- Diabetic Foot Ulcer Assessment and Management
- Cancer, Stress, Anesthesia, and Immune Response
- Advanced Photocatalysis Techniques
- Neonatal Respiratory Health Research
- ATP Synthase and ATPases Research
- Cancer-related molecular mechanisms research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Urinary Bladder and Prostate Research
- Lipid metabolism and disorders
- Traditional Chinese Medicine Analysis
- Cancer, Hypoxia, and Metabolism
- Autophagy in Disease and Therapy
Wenzhou Medical University
2015-2025
First Affiliated Hospital of Wenzhou Medical University
2015-2025
Wenzhou Municipal Sci-Tech Bureau
2022
Zhongnan Hospital of Wuhan University
2018
Wuhan University
2018
First Affiliated Hospital of Soochow University
2016
Soochow University
2016
Chinese Academy of Sciences
2012
Shenzhen Institutes of Advanced Technology
2012
Chinese University of Hong Kong
2012
BACKGROUND: Regional anesthesia such as interscalene brachial plexus block (ISBPB) with intermediate cervical (ICPB) is generally a preferred choice for clavicular surgery. However, various studies have shown that these blocks, especially ISBPB, could cause phrenic nerve paralysis and decrease diaphragmatic motion. The study aimed to evaluate the efficacy of clavipectoral fascial plane (CPB), an alternative technique ICPB, in reducing hemidiaphragmatic during midshaft METHODS: Forty patients...
Abstract Background Balanced propofol sedation is extensively used in endoscopic retrograde cholangiopancreatography (ERCP), but sedation-related adverse events (SRAEs) are common. In various clinical settings, the combination of dexmedetomidine with opioids and benzodiazepines has provided effective increased safety. The aim this investigation was to compare efficacy safety for during ERCP. Methods Forty-one patients were randomly divided into two groups: (DEX) group (PRO) group. Patients...
In Brief BACKGROUND: Acute lung injury is a recognized complication of lower limb ischemia–reperfusion that has been demonstrated experimentally and in the clinical setting aortic surgery. The application tourniquet can cause orthopedic We studied effect unilateral thigh tourniquet–induced on pulmonary function, role ischemic preconditioning attenuating dysfunction. METHODS: Thirty ASA I or II patients scheduled for extremity surgery were randomized into 2 groups: group with...
Battery charger plays an important role in the battery and electric vehicle technology. Due to on-board type of it should be light weight occupy less space as on all time, so smaller better course, is very minimize cost charger. For a plug-in hybrid (PHEV), when charging from grid, parked. The traction system components are normally not engaged during thus possible reconfigure these for system. In this paper, innovative integrated presented. operation mode can divided into three modes:...
Reperfusion after tourniquet use can induce inflammation and cause remote organ injury. We evaluated the therapeutic effect of transcutaneous electrical acupoint stimulation (TEAS) on inflammatory mediators lung function in patients receiving lower limb tourniquets. Forty undergoing unilateral extremity surgery with were randomly assigned to two groups: TEAS group ischemia-reperfusion (I/R) group. The C-C motif chemokine ligand 2 (CCL2), C-X-C 8 (CXCL8), interleukin-1 (IL-1), interleukin-6...
Background: Cough is one of the most common complications following intravenous administration sufentanil during anesthesia induction. The study aimed to investigate protective effect alfentanil, afentanyl derivative with short onset time and duration, in reducing sufentanil-induced cough. Patients methods: Eighty patients that scheduled for thyroid surgery under general were randomly divided into alfentanil group normal saline group, 40 cases per group. received 2 μg/kg prior injection...
This study was aimed to investigate the protective effect of methylene blue against lung injury induced by reperfusion ischemic hindlimb in a rat model.Twenty-four healthy adult male Sprague-Dawley rats were equally randomized into three groups: sham (SM) group, ischemia (IR) and (MB) group. Rats both IR MB groups subjected 4 h clamping left femoral artery then followed reperfusion. Treatment with 1% (50 mg/kg) administrated intraperitoneally at 10 min prior After reperfusion,...
Both apoptosis and necroptosis have been recognized to be involved in ischemia reperfusion-induced lung injury. We aimed compare the efficacies of therapies targeting determine if there is a synergistic effect between two reducing reperfusion injury.Forty Sprague-Dawley rats were randomized into 5 groups: sham (SM) group, (IR) necrostatin-1+ischemia (NI) carbobenzoxy-Val-Ala-Asp-fluoromethylketone+ischemia (ZI) necrostatin-1+carbobenzoxy-Val-Ala-Asp-fluoromethylketone+ischemia (NZ) group....
Background . Sphingosine-1-phosphate (S1P) is a biologically active lysophospholipid mediator involved in modulating inflammatory process. We investigated the effects of FTY720, structural analogue S1P after phosphorylation, on lung injury induced by hindlimb ischemia reperfusion (IR) rats. Methods Fifty Sprague-Dawley rats were divided into groups SM, IR, F3, F5, and F10. Group SM received sham operation, bilateral IR was established group IR. The F10 pretreated with 3, 5, 10 mg/kg/d FTY720...
Remote ischemic pre‑conditioning (RIPC) may have a protective effect on myocardial injury associated with cardiac bypass surgery (CPB). The objective of the present study was to investigate RIPC ischemia/reperfusion (I/R) and assess underlying mechanisms. A total 241 patients who underwent valve replacement were randomly assigned receive either (n=121) or control group (n=120). primary endpoint peri‑operative (PMI), which determined by serum Highly sensitive troponin T (hsTnT). secondary...
Postoperative cognitive dysfunction (POCD) is a common complication after cardiac surgery that influences the clinical outcomes and quality of life patients. This study aimed to evaluate effects Shenmai injection (SMI) on POCD patients who underwent valve replacement under cardiopulmonary bypass (CPB). prospective, randomized, controlled trial was conducted from September 2014 January 2017. Eighty-eight receiving CPB were randomized into control (C) or SMI (S) group. (0.6 mL/kg) administered...
Tourniquet has been considered as a recognized cause of lower limb ischemia-reperfusion injury in the orthopedic field. This study investigates pulmonary function after tourniquet deflation and protective effect Shenmai injection (SMI), traditional Chinese medicine.Twenty-eight patients undergoing extremity surgery were randomized into control group (group C) SMI S), 14 each group. Blood gas circulating indicators (malondialdehyde, interleukin [IL]-6, IL-8) measured immediately before...