Andrew Schachat

ORCID: 0000-0003-0964-3283
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Retinal and Optic Conditions
  • Ocular Oncology and Treatments
  • Glaucoma and retinal disorders
  • Retinal Development and Disorders
  • Retinal and Macular Surgery
  • Ocular Diseases and Behçet’s Syndrome
  • Intraocular Surgery and Lenses
  • Drug-Induced Ocular Toxicity
  • CNS Lymphoma Diagnosis and Treatment
  • Pharmaceutical industry and healthcare
  • Cutaneous Melanoma Detection and Management
  • Ophthalmology and Visual Impairment Studies
  • Meta-analysis and systematic reviews
  • Systemic Lupus Erythematosus Research
  • Lymphoma Diagnosis and Treatment
  • Ocular Infections and Treatments
  • Academic Publishing and Open Access
  • Vascular Malformations Diagnosis and Treatment
  • Melanoma and MAPK Pathways
  • Acute Myeloid Leukemia Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Retinopathy of Prematurity Studies
  • melanin and skin pigmentation

Cleveland Clinic
2015-2025

Cleveland Eye Clinic
2015-2025

RELX Group (United States)
2004-2023

Faculty of 1000 (United States)
2020-2023

Cleveland Clinic Lerner College of Medicine
2020-2022

Johns Hopkins University
2001-2020

Johns Hopkins Medicine
2000-2020

The California Eye Institute
2019

Ophthalmology Associates (United States)
2003-2018

Case Western Reserve University
2016

Objectives: To report initial mortality findings from the Collaborative Ocular Melanoma Study (COMS) randomized clinical trial of iodine 125 brachytherapy vs enucleation for treatment choroidal melanoma.Methods: Patients were evaluated eligibility at 43 participating centers in United States and Canada.Eligible consenting patients assigned randomly time enrollment to or I brachytherapy.Patients examined specified intervals after data collection purposes.Findings presented herein are based on...

10.1001/archopht.119.7.969 article EN Archives of Ophthalmology 2001-07-01

Intravenous fluorescein angiography is a commonly performed and extraordinarily valuable diagnostic procedure. The frequency of adverse reactions after has varied considerably in previous reports. In prospective study 2789 angiographic procedures 2025 patients, the authors found that percentage depended strongly on patient's history. Overall, followed 4.8% procedures. These included nausea (2.9%), vomiting (1.2%), flushing/itching/hives (0.5%), other (dyspnea, syncope, excessive sneezing)...

10.1016/s0161-6420(91)32165-1 article EN cc-by-nc-nd Ophthalmology 1991-07-01

10.1016/s0002-9394(98)00039-7 article EN American Journal of Ophthalmology 1998-06-01

<h3>Objective</h3> To describe fluorescein angiographic guidelines for the use of verteporfin therapy in patients with subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) or other conditions based on 2-year vision outcomes from Treatment Age-Related Macular Degeneration With Photodynamic Therapy (TAP) Investigation and Verteporfin Therapy(VIP) Trial. <h3>Methods</h3> Three multicenter, double-masked, placebo-controlled randomized clinical trials...

10.1001/archopht.121.9.1253 article EN Archives of Ophthalmology 2003-09-01

• We prospectively examined the eyes of 120 patients with leukemia. Only 38% had normal results examination. Leukemic infiltrates were present in 3% patients, other findings related to leukemia seen 39% and 20% unrelated abnormalities. Visual loss was at least 5% this study.

10.1001/archopht.1989.01070010715033 article EN Archives of Ophthalmology 1989-05-01

• The Bardet-Biedl and Laurence-Moon syndromes are distinct entities. nosology of five combining ocular and/or auditory defects, mental retardation, genital hypoplasia, obesity, digital anomalies is reviewed. A 32-month-old boy had an unusual condition that may represent a sixth entity.

10.1001/archopht.1982.01030030287011 article EN Archives of Ophthalmology 1982-02-01

Although an accurate uveal melanoma staging system is needed to improve research and patient care, the evaluation of eye cancer systems requires international multicenter data sharing acquire a statistically significant analysis.To assess mortality outcomes associated with according 7th edition American Joint Committee on Cancer's AJCC Cancer Staging Manual.A committee was formed create patient-specific fields for patients melanoma. Ten subspecialty ophthalmic oncology centers from 4...

10.1001/jamaophthalmol.2014.5395 article EN JAMA Ophthalmology 2015-01-02

PurposeTo assess of the effect local recurrence uveal melanoma on metastasis using a multicenter international tumor registry.DesignRetrospective study an online registry.ParticipantsPatients with diagnosed between 2001 and 2011.MethodsA committee was formed to create patient-specific data fields. Ten subspecialty ophthalmic oncology centers from 4 continents shared data. Patient selection criteria included diagnosis adequate records allow staging by American Joint Committee Cancer (AJCC)...

10.1016/j.ophtha.2015.09.014 article EN cc-by-nc-nd Ophthalmology 2015-10-25

<h3>Objective</h3> To evaluate the anatomical and visual outcomes of patients treated with ocriplasmin for treatment symptomatic vitreomacular adhesion (sVMA), including traction syndrome macular holes. <h3>Design</h3> Retrospective, interventional, single centre, case series. <h3>Participants</h3> Patients sVMA. <h3>Intervention</h3> were a intravitreal injection 0.125 mg (Jetrea, Thrombogenics Inc, USA, Alcon/Novartis EU) reconstitution technique recommended by manufacturer. <h3>Main...

10.1136/bjophthalmol-2013-304219 article EN British Journal of Ophthalmology 2013-12-19

<h3>Importance</h3> The Diabetic Retinopathy Clinical Research Network (DRCR Network), sponsored by the National Eye Institute, reported results of a comparative effectiveness randomized clinical trial (RCT) evaluating 3 anti–vascular endothelial growth factor (anti-VEGF) agents aflibercept (2.0 mg), bevacizumab (1.25 and ranibizumab (0.3 mg) for treatment diabetic macular edema (DME) involving center retina associated with visual acuity loss. many important findings RCT prompted American...

10.1001/jamaophthalmol.2015.4110 article EN JAMA Ophthalmology 2015-10-29

<h3>Objective:</h3> To report on the frequency of features agerelated macular degeneration in a black population based fundus photograph gradings. <h3>Design:</h3> Population-based study. <h3>Setting:</h3> Barbados, West Indies. <h3>Study Population:</h3> Residents selected by random sample Barbados-born citizens, aged 40 to 84 years. <h3>Main Outcome Measure:</h3> Gradings from 30° stereoscopic photographs. <h3>Results:</h3> Black participants (n=3444) completed examinations at study site...

10.1001/archopht.1995.01100060054032 article EN Archives of Ophthalmology 1995-06-01
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