A5059946887- Anesthesia and Pain Management
- Neurological and metabolic disorders
- HIV/AIDS drug development and treatment
- Pulmonary Hypertension Research and Treatments
- Inflammasome and immune disorders
- Shoulder Injury and Treatment
- Anesthesia and Sedative Agents
- HIV-related health complications and treatments
- HIV/AIDS Research and Interventions
- Cardiac, Anesthesia and Surgical Outcomes
- HIV Research and Treatment
- Spine and Intervertebral Disc Pathology
- Infectious Encephalopathies and Encephalitis
- Orthopedic Surgery and Rehabilitation
- Neurosurgical Procedures and Complications
- Disaster Response and Management
- Pain Management and Treatment
- Nausea and vomiting management
- Neonatal and fetal brain pathology
- Nerve Injury and Rehabilitation
- Ophthalmology and Eye Disorders
- Neurological disorders and treatments
- Acute Lymphoblastic Leukemia research
- Optimism, Hope, and Well-being
- Spondyloarthritis Studies and Treatments
Janssen (Switzerland)
2024
Janssen (Italy)
2020-2022
University of Milan
2019-2020
Ospedale Maggiore
2019
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2019
University of Milano-Bicocca
2012-2014
Azienda Ospedaliero-Universitaria Careggi
1992-1997
Ospedali Riuniti Umberto I
1985
University of Sassari
1967-1969
The authors retrospectively reviewed the clinical records of 196 patients with dementia treated memantine for at least 6 months. Eleven (5.6%) developed treatment-induced agitation. At chi-square analysis, they were significantly more likely to have a history similar side effects from other medications acting on central nervous system in comparison group without agitation, suggesting neurochemical susceptibility. A trend toward greater prevalence was also present ischemic cardiopathy and...
Ninety patients undergoing scheduled upper limb orthopaedic surgery were studied to determine the optimal anaesthetic dose using 'orthogonal two-needle technique'. The randomly assigned one of three groups receive different volumes (20, 30 and 40 mL) (n = 30) solution (a mixture equal parts 0.5% bupivacaine with adrenaline 1:200,000 2% lignocaine). A significant correlation was found between volume injected spread for all tested areas. better analgesic major branches plexus obtained when...
Objective: This study investigates the effectiveness and tolerability of switching to a darunavir/cobicistat (DRV/c)-based antiretroviral regimen from ritonavir-boosted protease inhibitor (PI/r)-based in virologically suppressed HIV-positive patients. DRV trough values were also investigated. Setting: Prospective, multicenter, single-country, noninterventional cohort study. Methods: included patients on PI/r-based ART for at least 12 months having plasma HIV-1 RNA <50 copies/mL since 6...
This prospective, multicenter, non-interventional cohort study enrolling human immunodeficiency virus (HIV)-1-infected, virally suppressed adult outpatients in Italy aimed to describe results obtained from patient-reported outcome questionnaires regarding treatment satisfaction and symptom perceptions HIV-1-positive patients who switched cobicistat-boosted darunavir antiretroviral regimens, coming ritonavir-boosted protease inhibitors. Patients entered this between June 2016 February 2017,...
Abstract Background The thiopurine S-methyltransferase (TPMT)/azathioprine (AZA) gene-drug pair is one of the most well-known pharmacogenetic markers. Despite this, few studies investigated implementation TPMT testing and combined evaluation genotype phenotype in multidisciplinary clinical settings where patients are undergoing chronic therapy with AZA. Methods A total 356 AZA-treated for autoimmune diseases were enrolled. DNA was isolated from whole blood samples analyzed c.460G>A...
Ninety patients undergoing scheduled upper limb orthopaedic surgery were studied to determine the optimal anaesthetic dose using 'orthogonal two-needle technique'. The randomly assigned one of three groups receive different volumes (20, 30 and 40mL) (n=30) solution (a mixture equal parts 0.5% bupivacaine with adrenaline 1:200 000 2% lignocaine). A significant correlation was found between volume injected spread for all tested areas. better analgesic major branches plexus obtained when...
Servizio di Anestesia e Rianimazione, Centro Traumatologic Ortopedico, Ospedali Riuniti Careggi, Largo Parlagi 1, Florence, Italy
Abstract Background Pulmonary arterial hypertension (PAH) is a rare, progressive disease leading to right-sided heart failure. The interest in risk assessment based on non-invasive parameters growing, and insights from clinical practice are needed this regard. INSPECTIO an Italian observational study aimed at filling knowledge gap. results of interim analysis month 12 presented below. Purpose primary objective was assess the change baseline number low-risk among World Health Organization...
A randomized study was carried out on 160 patients aged 30-60 years with the aim of finding a method preventing postdural puncture headache (PDPH). In Taylor's lumbosacral approach to subarachnoid space, two different needle sizes were used (21-gauge versus 25-gauge) for injecting anaesthetic solution. Our results show an overall incidence PDPH in nearly 8% patients, no significant difference related size employed. Patients showed mild symptoms which disappeared short time and none needed...
<h3>Background</h3> Familial Mediterranean fever (FMF) and tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) represent two forms of monogenic autoinflammatory diseases, characterized by recurrent auto-limiting attacks systemic inflammation. Both the diseases are due to aberrant activation inflammasome platforms. Several variants in <i>Mediterranean Fever (MEFV)</i> gene <i>TNF Receptor Superfamily Member 1A (TNFRS1A)</i> respectively at basis FMF TRAPS....
<b>Background:</b> pulmonary arterial hypertension (PAH) is a chronic, progressive disease; the use of narrative medicine may help investigate patient perspective, their self-perception and quality life to better address burden disease. <b>Aims:</b> gain insights into how PAH caregivers experience PAH, by evaluating plots collected within INSPECTIO study. <b>Methods:</b> INSPECTIO is an ongoing, observational, multicentre, prospective study patients with PAH. We aimed enrol 200 already...