A5088708912- Cancer Genomics and Diagnostics
- Endometriosis Research and Treatment
- Acute Myeloid Leukemia Research
- Reproductive System and Pregnancy
- Hematological disorders and diagnostics
- Genetic factors in colorectal cancer
- Plant Stress Responses and Tolerance
- Plant nutrient uptake and metabolism
- T-cell and B-cell Immunology
- Urticaria and Related Conditions
- Immune Response and Inflammation
- Plant Micronutrient Interactions and Effects
- Epigenetics and DNA Methylation
- Immune Cell Function and Interaction
- Effects of Radiation Exposure
- Cancer, Lipids, and Metabolism
- Endometrial and Cervical Cancer Treatments
- Gynecological conditions and treatments
- Nanoplatforms for cancer theranostics
- Contact Dermatitis and Allergies
- Genetic Mapping and Diversity in Plants and Animals
- Mast cells and histamine
- Reproductive Biology and Fertility
- Genetics and Plant Breeding
- Genetic and phenotypic traits in livestock
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2025
Peking Union Medical College Hospital
2024-2025
Inner Mongolia Agricultural University
2025
National Clinical Research Center for Digestive Diseases
2024
Hebei Medical University
2024
Academia Sinica
2019
Academy of Medical Sciences
2019
Institute of Hematology & Blood Diseases Hospital
2019
Shanghai Institute of Hematology
2018
Shanghai Jiao Tong University
2018
The authors studied the influence of vitamin A deficiency on immediate and delayed type hypersensitivity as well granulocyte-mediated inflammatory reactions in depleted control rats. number circulating leucocytes was 43% higher deficient than animals. leucocytosis a result general increase white blood cells not due to an one particular type. ratio between CD4+ CD8+ T unchanged. rats had four times T-cell proliferative response two interferon-gamma production vitro In accordance, DTH reaction...
Abstract Human leukocyte antigen‐G (HLA‐G) molecule exerts multiple immunoregulatory functions that have been suggested to contribute the immune evasion of tumour cells. Studies on HLA‐G expression in malignant haematopoietic diseases are controversial, and this context limited. In current study, was analysed different types patients: de novo acute myeloid leukaemia (AML, n = 54), B cell lymphoblastic (B‐ALL, 13), chronic (CML, 9) myelodysplastic syndrome (MDS, 11). observed 18.5% cases AML,...
Oat is a crop and forage species with rich nutritional value, capable of adapting to various harsh growing environments, including dry poor soils. It plays an important role in agricultural production sustainable development. However, the molecular mechanisms underlying response oat drought stress remain unclear, warranting further research. In this study, we conducted pot experiment drought-resistant cultivar JiaYan 2 (JIA2) water-sensitive BaYou 9 (BA9) during booting stage under three...
The oat is a crop and forage species with rich nutritional value, capable of adapting to various harsh growing environments, including dry poor soils. It plays an important role in agricultural production sustainable development. However, the molecular mechanisms underlying responses drought stress remain unclear, warranting further research. In this study, we conducted pot experiment drought-resistant cultivar JiaYan 2 (JIA2) water-sensitive BaYou 9 (BA9) during booting stage under three...
Soil salinity is among the crucial factors influencing agricultural productivity of crops, including oat. The respiratory metabolic pathways are great significance for plants to adapt salt stress, but current research limited and there few reports on salt-tolerant crops such as oat, which necessary conduct in-depth research. In this study, we conducted a pot experiment determine effects stress oat root growth metabolism. Three levels—control (CK), moderate, severe—were applied compare...
Abstract Introduction Cytogenetically normal acute myeloid leukemia ( CN ‐ AML ), which accounted for nearly half of total patients, is a highly heterogeneous subset . The specific genetic profile and the ethnic features are worth to be studied. Methods Using deep sequencing technology, we detected mutation pattern 39 genes in 152 Chinese patients analyzed their clinical features. Results A 503 mutations were identified 145 (95.4%) with median number 3 per case. Nine NPM 1, CEBPA , DNMT 3A,...
Activation of B lymphocytes involves binding antigen to the specific receptor and signalling through several membrane coreceptors, which CD19 has been found play a pivotal role as response regulator. Although previous studies in gene knockout mice have demonstrated that antibody responses T‐cell‐dependent antigens are strongly impaired absence this coreceptor, little is known about consequences deficiency for interaction between T cells. Here we report Th2 co‐ordinated B‐cell differentiation...
Ovarian cancer (OC) is a major cause of mortality in women worldwide. Due to the occult onset OC, its nonspecific clinical symptoms early phase, and lack effective diagnostic tools, most OC patients are diagnosed at an advanced stage. In this study, shallow whole-genome sequencing was utilized characterize fragmentomics features circulating tumor DNA (ctDNA) patients. By applying machine learning model, multiclass data achieved mean area under curve (AUC) 0.97 (95% CI 0.962-0.976) for...
Little is known about the role of protective effects granulocyte colony-stimulating factor (G-CSF) in patients after radiotherapy. The aim present study was to explore prophylactic long-acting on febrile neutropenia (FN) and myelosuppression chemotherapy with gynecologic malignancies pelvic Patients voluntarily participated a group (long-acting G-CSF for all cycles) control (short-acting G-CSF) they were educated utilization. incidences FN myelosuppression, as well adverse events, compared...
Background: Acute leukemias are the most common diagnostic group of childhood cancer. Despite constituting only 20% pediatric acute leukemias, AML (APL excluded) is overtaking lymphoblastic leukemia (ALL) as leading cause leukemic mortality, suggesting that precision medicine for needs to be improved. Now therapy children patients relies on accurate detection mutant spectrum. Bone marrow was commonly used in detecting genetic mutations past years, but bone aspiration invasive procedure and...