Felipe C. Vechin

ORCID: 0000-0003-0975-8654
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About
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Research Areas
  • Sports Performance and Training
  • Muscle metabolism and nutrition
  • Exercise and Physiological Responses
  • Cardiovascular and exercise physiology
  • Sports injuries and prevention
  • Nutrition and Health in Aging
  • Adipose Tissue and Metabolism
  • Physical Education and Gymnastics
  • Muscle Physiology and Disorders
  • Physical Activity and Health
  • Cancer survivorship and care
  • Genetics and Physical Performance
  • Muscle activation and electromyography studies
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Body Composition Measurement Techniques
  • Cardiovascular Effects of Exercise
  • Circular RNAs in diseases
  • MicroRNA in disease regulation
  • Sex and Gender in Healthcare
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Healthcare Regulation
  • Heart Rate Variability and Autonomic Control
  • Cardiovascular Function and Risk Factors
  • Spaceflight effects on biology
  • Health and Wellbeing Research

Universidade de São Paulo
2014-2024

Centro de Pesquisas Oncológicas
2024

Universidade Federal de São Carlos
2016-2022

University of North Texas
2019

Universidade Estadual de Campinas (UNICAMP)
2010-2016

McMaster University
2016

Dana-Farber Cancer Institute
2016

Harvard University
2016

Australian Catholic University
2016

Liverpool John Moores University
2016

Skeletal muscle hypertrophy is one of the main outcomes from resistance training (RT), but how it modulated throughout still unknown. We show that changes in myofibrillar protein synthesis (MyoPS) after an initial exercise (RE) bout first week RT (T1) were greater than those seen post-RE at third (T2) and tenth (T3) RT, with values being similar T2 T3. Muscle damage (Z-band streaming) was highest during recovery T1, lower minimal When highest, so integrated MyoPS (at T1), neither related to...

10.1113/jp272472 article EN The Journal of Physiology 2016-05-24

High-intensity resistance training (HRT) has been recommended to offset age-related loss in muscle strength and mass. However, part of the elderly population is often unable exercise at high intensities. Alternatively, low-intensity with blood flow restriction (LRT-BFR) emerged. The purpose this study was compare effects LRT-BFR HRT on quadriceps mass elderly. Twenty-three individuals, 14 men 9 women (age, 64.04 ± 3.81 years; weight, 72.55 16.52 kg; height, 163 11 cm), undertook 12 weeks...

10.1519/jsc.0000000000000703 article EN The Journal of Strength and Conditioning Research 2014-09-27

The aim of this present study was to investigate on the effects concurrent training with blood flow restriction (BFR-CT) and (CT) aerobic fitness, muscle mass strength in a cohort older individuals. 25 healthy adults (64.7±4.1 years; 69.33±10.8 kg; 1.6±0.1 m) were randomly assigned experimental groups: CT (n=8, endurance (ET), 2 days/week for 30–40 min, 50–80% VO<sub>2peak</sub> RT, days/week, leg press 4 sets 10 reps at 70–80% 1-RM 60 s rest), BFR-CT (n=10, ET, similar CT, but resistance...

10.1055/s-0034-1390496 article EN International Journal of Sports Medicine 2015-02-20

The postmenopausal phase has been considered an aggravating factor for developing metabolic syndrome. Notwithstanding, no studies have as yet investigated the effects of resistance training on syndrome in women. Thus, purpose this study was to verify whether could reduce risk women.Twenty women were randomly assigned a protocol (n = 10, 53.40 ± 3.95 years, 64.58 9.22 kg) or control group 53.0 5.7 64.03 5.03 kg). In protocol, ten exercises performed, with 3 × 8-10 maximal repetitions three...

10.2147/cia.s44245 article EN cc-by-nc Clinical Interventions in Aging 2013-09-01

Using a within-subject unilateral design, we demonstrated that increasing resistance training (RT) volume may be simple, effective strategy to improve muscle hypertrophy and strength gains among older adults who do not respond low-volume RT. In addition, it could most likely used further hypertrophic outcomes in responders.

10.1152/japplphysiol.00670.2023 article EN Journal of Applied Physiology 2024-01-04

Damas, F, Barcelos, C, Nóbrega, SR, Ugrinowitsch, Lixandrão, ME, Santos, LMEd, Conceição, MS, Vechin, FC, and Libardi, CA. Individual muscle hypertrophy strength responses to high vs. low resistance training frequencies. J Strength Cond Res 33(4): 897-901, 2019-The aim of this short communication was compare the individual mass gains with (HF) (LF) (RT) frequencies using data from our previous study. We used a within-subject design in which 20 subjects had one leg randomly assigned HF (5×...

10.1519/jsc.0000000000002864 article EN The Journal of Strength and Conditioning Research 2018-10-05

Satellite cells (SC) are associated with skeletal muscle remodelling after damage and/or extensive hypertrophy resulting from resistance training (RT). We recently reported that early increases in protein synthesis (MPS) during RT appear to be directed toward repair, but MPS contributes progressive attenuation. However, modulations acute-chronic SC content the initial (1st-wk: high damage), (3rd-wk: attenuated and later (10th-wk: no damage) stages is not well characterized. Ten young men (27...

10.1371/journal.pone.0191039 article EN cc-by PLoS ONE 2018-01-11

Extended periods of resistance training (RT) induce muscle hypertrophy. Nevertheless, to date, no study has investigated the time window necessary observe significant changes in cross-sectional area (CSA) older adults. Therefore, this course hypertrophy after 10 weeks (20 sessions) RT elderly. Fourteen healthy subjects were randomly allocated either (n: 6) or control group 8). The was composed 4 sets × repetitions (70-80% 1 repetition maximum [1RM]) a leg press machine. vastus lateralis...

10.1519/jsc.0000000000001019 article EN The Journal of Strength and Conditioning Research 2015-06-24

Introduction Exercise performed with blood flow restriction simultaneously enhances the acute responses to both myogenic and mitochondrial pathways roles in training adaptation. We investigated isoform-specific gene expression of peroxisome proliferator-activated receptor gamma coactivator 1 selected target genes proteins regulating skeletal muscle Methods Nine healthy, untrained males participated a randomized, counterbalanced, crossover design which each subject completed bout...

10.1249/mss.0000000000000970 article EN Medicine & Science in Sports & Exercise 2016-04-29

Exercise-induced microRNA (miRNA) expression has been implicated in the regulation of skeletal muscle plasticity. However, specificity and acute time course miRNA after divergent exercise modes are unknown. In a randomized crossover design, we compared profile eight miRNAs previously reported to be involved development, growth, maintenance bout either resistance (RE), high-intensity interval (HIIE), concurrent exercises (CE).Nine untrained young men (23.9 ± 2.8 yr, 70.1 14.9 kg, 177.2 3.0...

10.1249/mss.0000000000002632 article EN Medicine & Science in Sports & Exercise 2021-02-19

We aimed to investigate whether muscle fiber cross-sectional area (fCSA) and associated molecular processes could be differently affected at the group individual level by manipulating resistance training (RT) variables. Twenty resistance-trained subjects had each leg randomly allocated either a standard RT (RT-CON: without specific variables manipulations) or variable (RT-VAR: manipulation of load, volume, action, rest interval session). Muscle fCSA, satellite cell (SC) pool, myonuclei...

10.1111/sms.14134 article EN Scandinavian Journal of Medicine and Science in Sports 2022-01-29

Methods: The study participants performed maximal concentric, isometric, and eccentric contractions of the elbow flexors knee extensors using an isokinetic dynamometer following a crossover design. Changes in dependent variables were compared mixed model analysis (limb versus age). Results: main results demonstrated that eccentric, mean contraction torques for significantly ( P < 0.05) higher younger men than elderly men. On other hand, no statistically significant difference > was found...

10.2147/cia.s41838 article EN cc-by-nc Clinical Interventions in Aging 2013-04-01

We aimed to investigate the mechanisms underlying muscle growth after 12 weeks of resistance training performed with blood flow restriction (RT-BFR) and high-intensity (HRT) in older individuals. Participants were allocated into following groups: HRT, RT-BFR, or a control group. High-throughput transcriptome sequencing was by Illumina HiSeq 2500 platform. HRT RT-BFR presented similar increases quadriceps femoris cross-sectional area, few genes differently expressed between interventions. The...

10.1139/apnm-2018-0146 article EN Applied Physiology Nutrition and Metabolism 2018-07-12

ABSTRACT Introduction DNA methylation regulates exercise-induced changes in the skeletal muscle transcriptome. However, specificity and time course responses myogenic regulatory factors mRNA expression after divergent exercise modes are unknown. Purpose This study aimed to compare for selected ( MYOD1 , MYF5 MYF6 ) immediately after, 4 h 8 a single bout of resistance (RE), high-intensity interval (HIIE), concurrent (CE). Methods Nine healthy but untrained males (age, 23.9 ± 2.8 yr; body...

10.1249/mss.0000000000003049 article EN Medicine & Science in Sports & Exercise 2022-09-22
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