A5070528452- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Advanced MRI Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Health and Disease Prevention
- MRI in cancer diagnosis
- Vascular Malformations Diagnosis and Treatment
- Coronary Interventions and Diagnostics
- Peripheral Artery Disease Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Moyamoya disease diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
- Stroke Rehabilitation and Recovery
- Aortic Disease and Treatment Approaches
- Cerebral Venous Sinus Thrombosis
- Cerebrospinal fluid and hydrocephalus
- Cardiac Imaging and Diagnostics
- Vascular Anomalies and Treatments
- Cardiovascular Issues in Pregnancy
- Viral-associated cancers and disorders
- Cancer Treatment and Pharmacology
- Computer Graphics and Visualization Techniques
- Renal and Vascular Pathologies
University of Illinois Chicago
2016-2025
Medtronic (China)
2025
Indo-American Center
2022-2023
Yangzhou University
2019
Neurological Surgery
2004-2018
United States Nuclear Regulatory Commission
2018
University of Chicago Medical Center
2018
University of Pennsylvania
2015
University of California, Los Angeles
2015
Resonance Research (United States)
2015
Atherosclerotic vertebrobasilar (VB) occlusive disease is a significant etiology of posterior circulation stroke, with regional hypoperfusion as an important potential contributor to stroke risk.To test the hypothesis that, among patients symptomatic VB stenosis or occlusion, those distal blood flow compromise measured by large-vessel quantitative magnetic resonance angiography (QMRA) are at higher risk subsequent stroke.A prospective, blinded, longitudinal cohort study was conducted 5...
Measurement of volume flow rates in major cerebral vessels can be used to evaluate the hemodynamic effects cerebrovascular disease. However, both age and vascular anatomy affect independent We prospectively evaluated 325 healthy adult volunteers using phase contrast quantitative magnetic resonance angiography characterize these on vessel establish clinically useful normative reference values. Flows were measured intracranial extracranial vessels. The cohort ranged from 18 84 years old, with...
Abstract OBJECTIVE: There has been a resurgence of interest in selective extracranial-intracranial bypass for revascularization cerebrovascular occlusive disease. We evaluated the usefulness intraoperative blood flow measurements predicting graft success after bypass. METHODS: A retrospective review 51 cases purposes augmentation setting disease was performed. In all cases, free from cut end donor vessel, termed flow, measured. The index (CFI) (bypass [ml/min] / [ml/min]) derived and...
Background and Purpose— The hemodynamic effects of extracranial carotid stenosis on intracranial blood flow are not well characterized. We sought to determine the impact degree stenosis, length, residual lumen in patients with stenosis. Methods— Carotid who had undergone both vessel rate measurements using quantitative magnetic resonance angiography digital subtraction were examined. anatomic relative ipsilateral internal artery (ICA) ipsilateral-to-contralateral middle cerebral (MCA) ratio...
The hemodynamic force of wall shear stress (WSS) has demonstrated a critical role in atherogenesis.To study the effect age and gender on mean WSS (MWSS) values major cerebral arteries.Thirteen arterial location sites 301 healthy (157 M, 144 F; 47 ± 15 years; range 18-84 years old) were studied. Quantitative magnetic resonance angiography was used to obtain volume flow diameter, subsequently calculate MWSS via Hagen-Poiseuille equation.MWSS decreased significantly with all vessels, declining...
Background and Purpose— Atherosclerotic vertebrobasilar disease is an important cause of posterior circulation stroke. To examine the role hemodynamic compromise, a prospective multicenter study, Vertebrobasilar Flow Evaluation Risk Transient Ischemic Attack Stroke (VERiTAS), was conducted. Here, we report clinical features vessel flow measurements from study cohort. Methods— Patients with recent transient ischemic attack or stroke ≥50% atherosclerotic stenosis occlusion in vertebral basilar...
Object To date, angiography has been the primary modality for assessing graft patency following extracranial–intracranial bypass. The utility of a noninvasive and quantitative method bypass function postoperatively was evaluated using magnetic resonance (MR) angiography. Methods One hundred one cases surgery performed over 5.5-year period at single institution were reviewed. In 62 cases, both angiographic MR data available. Intraoperative flow measurements available in 13 which during early...
<h3>BACKGROUND AND PURPOSE:</h3> Large-vessel cerebral blood flow quantification has emerged as a potential predictor of stroke risk. QMRA uses phase-contrast techniques to noninvasively measure vessel flows. To evaluate the in vivo accuracy for measuring effects progressive arterial stenosis, we compared this technique with invasive measurements from sonographic transit-time probe canine model. <h3>MATERIALS METHODS:</h3> A was implanted around CCA hound dogs (<i>n</i> = 4) under general...
BACKGROUND: Demographics and comorbid conditions play a role in vascular health, yet their specific impact on cerebrovascular bypass patency remains unclear. METHODS: An institutional database of 357 patients with intracranial procedures between August 2001 May 2022 was retrospectively reviewed. Patients for all causes (eg, aneurysm, atherosclerotic disease, moyamoya disease) were included. Medical history, surgical technique, flow-related measurements (intraoperatively quantitative magnetic...
Leptomeningeal collateral volume flow has not been previously quantified. Quantitative magnetic resonance angiography (QMRA) can determine in the large vessels of intracranial circulation.We reviewed consecutive QMRA studies performed between December 1, 2004 and August 30, 2005, for cases showing asymmetrically higher a posterior cerebral artery (PCA) just distal to origin communicating ipsilateral hemodynamic middle (MCA) or internal carotid lesion. The mean, range, standard deviation (SD)...
Background Posterior fossa arteriovenous malformations (AVMs) are considered to have a higher risk of poor outcome, as AVMs with associated aneurysms. We postulated that posterior may be more prone feeder vessel aneurysms, and aneurysmal source hemorrhage. Objective To examine the prevalence hemorrhagic AVM-associated Methods A retrospective review was performed attention paid location presence The hemorrhage status origin also reviewed. Results 571 were analyzed. Of 90 AVMs, 34 (37.8%) had...
Carotid artery stenting is an endovascular treatment option for patients with extracranial carotid stenosis. However, intracranial blood flow changes following have not been established.To determine the effects of on flow.Records who underwent at our institution between 2004 and 2012 had rates obtained pre- poststenting by use quantitative magnetic resonance angiography were retrospectively reviewed. Percentage stenosis, stenosis length, minimum vessel diameter measured from cerebral...
To determine the utility of digital subtraction angiography (DSA) in patients with unruptured intracranial aneurysms (UIA) detected on noninvasive imaging, such as magnetic resonance (MRA) and computed tomography (CTA). The follow-up untreated UIAs involves serial imaging; however, this diagnosis may be based false positive (FP) results. We examined incidence FPs our institutional series.DSAs performed at institution from January 2011 to June 2014 were retrospectively reviewed referred UIA...
Object. Balloon occlusion tests (BOTs) are performed to identify patients who at risk for ischemia and stroke following permanent internal carotid artery (ICA) occlusion. The object of this work was determine whether patient-specific blood flow modeling can be used in whom the BOT would not tolerated. Methods. test 16 underwent with continuous neurological electroencephalographic monitoring, followed by a hypotensive challenge. During hypotension tracer injected so that single-photon...
BACKGROUND: Graft selection in extracranial-intracranial bypass surgery for cerebral aneurysms has traditionally been based on clinical impression and operator preference. However, decision making can be optimized with a donor algorithm intraoperative flow data. OBJECTIVE: To present long-term follow-up quantitative assessment of sufficiency native donors selected this manner. METHODS: Patients anterior circulation intracranial using only (superficial temporal artery) the basis an over...
There is a growing research interest in quantifying blood flow distribution for the entire cerebral circulation to sharpen diagnosis and improve treatment options cerebrovascular disease of individual patients. We present methodology reconstruct subject-specific patterns accordance with physiological fluid mechanical principles optimally informed by vivo neuroimage data anatomy arterial rates. propose an inverse problem infer across visible portion network that best matches given set...
Background and Purpose- Cerebral hypoperfusion symptoms (defined as related to change in position, effort or exertion, recent antihypertensive medication) have been used stroke studies a surrogate for detecting hemodynamic compromise. However, the validity of these identifying flow compromise patients has not well established. We examined whether correlated with quantitative measurements prospective, observational VERiTAS study (Vertebrobasilar Flow Evaluation Risk Transient Ischemic Attack...