Matthew J. Sharman

ORCID: 0000-0003-1005-4793
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About
Contact & Profiles
Research Areas
  • Muscle metabolism and nutrition
  • Diet and metabolism studies
  • Exercise and Physiological Responses
  • Sports Performance and Training
  • Alzheimer's disease research and treatments
  • Diet, Metabolism, and Disease
  • Adipose Tissue and Metabolism
  • Nutritional Studies and Diet
  • Cardiovascular and exercise physiology
  • Dementia and Cognitive Impairment Research
  • Cholesterol and Lipid Metabolism
  • Hormonal and reproductive studies
  • Sports injuries and prevention
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Nutrition and Health in Aging
  • Tryptophan and brain disorders
  • Biochemical Acid Research Studies
  • Metabolism and Genetic Disorders
  • Genetics and Physical Performance
  • Stress Responses and Cortisol
  • Growth Hormone and Insulin-like Growth Factors
  • Cholinesterase and Neurodegenerative Diseases
  • High Altitude and Hypoxia
  • Obesity, Physical Activity, Diet
  • Pharmacological Effects and Assays

University of Tasmania
2013-2025

The University of Western Australia
2009-2017

RMIT University
2014

Edith Cowan University
2006-2013

Australian Alzheimer’s Research Foundation
2010

Hollywood Private Hospital
2009-2010

University of Connecticut
2001-2008

MetroHealth Medical Center
2006

Case Western Reserve University
2006

Lonza (United States)
2005

Peptide F [preproenkephalin (107–140)] has been shown to have stress-induced opiate-like activities with both analgesic and immune modulation characteristics. PURPOSE: The purpose of this study was determine the effects Vicopofen (hydrocodone bitartrate 7.5 mg ibuprofen 200mg), (200mg) placebo on proenkephalin following muscle damage induced via repeated eccentric actions (120% Concentric 1 RM). METHODS: Thirty-six healthy men (22.7 ± 0.9 yrs, 78.2 2.5 kg, 178.5 6.8 cm) underwent baseline...

10.1097/00005768-200205001-00389 article EN Medicine & Science in Sports & Exercise 2002-05-01

Abstract Objective To compare the effects of isocaloric, energy-restricted very low-carbohydrate ketogenic (VLCK) and low-fat (LF) diets on weight loss, body composition, trunk fat mass, resting energy expenditure (REE) in overweight/obese men women. Design Randomized, balanced, two diet period clinical intervention study. Subjects were prescribed (-500 kcal/day) diets: a VLCK with goal to decrease carbohydrate levels below 10% induce ketosis LF similar national recommendations...

10.1186/1743-7075-1-13 article EN cc-by Nutrition & Metabolism 2004-11-08

AbstractObjective: Very low-carbohydrate diets are widely used for weight loss yet few controlled studies have determined how these impact cardiovascular risk factors compared to more traditional low-fat diets. The primary purpose of this study was compare a very and diet on fasting blood lipids, LDL subclasses, postprandial lipemia, insulin resistance in overweight obese women.Methods: Thirteen normolipidemic, moderately (body fat >30%) women were prescribed two hypocaloric (−500 kcal/day)...

10.1080/07315724.2004.10719359 article EN Journal of the American College of Nutrition 2004-04-01

In recent years, it has become apparent that low-grade vascular inflammation plays a key role in all stages of the pathogenesis atherosclerosis. Weight loss been shown to improve blood inflammatory markers; however, is unknown if weight-loss diets varying macronutrient composition differentially affect responses. The primary purpose present study was compare very-low-carbohydrate diet and low-fat on biomarkers overweight men. randomized cross-over design, 15 men (body fat, >25%; body...

10.1042/cs20040111 article EN Clinical Science 2004-09-24

The purpose of this study was to investigate the effects a progressive resistance training program on myosin heavy chain isoform expression, fiber type, and capillarization in patients with symptomatic peripheral arterial disease. Patients were randomized either group (n = 11, mean ± SD, 70 6 years, 4 men, 7 women) or control 9, 66 5 women). sessions completed 3 times/week, using 2 sets various exercises, each performed for 8–15 repetitions. Muscle biopsies obtained before after 24 weeks...

10.1093/gerona/56.7.b302 article EN The Journals of Gerontology Series A 2001-07-01

We investigated the guinea pig, Cavia porcellus, as a model for Alzheimer's disease (AD), both in terms of conservation genes involved AD and regulatory responses these to known risk factor - high cholesterol intake. Unlike rats mice, pigs possess an Aβ peptide sequence identical human Aβ. Consistent with commonality between cardiovascular factors humans, we saw that diet leads up-regulation BACE1 (β-secretase) transcription down-regulation ADAM10 (α-secretase) which should increase release...

10.1371/journal.pone.0066235 article EN cc-by PLoS ONE 2013-06-21

MCGUIGAN, M. R. M., BRONKS, U. NEWTON, J. SHARMAN, C. GRAHAM, D. V. CODY, and W. KRAEMER. Muscle fiber characteristics in patients with peripheral arterial disease. Med. Sci. Sports Exerc., Vol. 33, No. 12, 2001, pp. 2016–2021. Purpose There have been conflicting reports of muscle type changes disease (PAD). The purpose this study was to examine the myosin heavy chain (MHC) expression as well histochemical gastrocnemius symptomatic PAD. Methods Needle biopsy specimens were obtained from...

10.1097/00005768-200112000-00007 article EN Medicine & Science in Sports & Exercise 2001-12-01

To investigate the effects of short-term, reduced-volume sprint interval training (SIT) compared to traditional exercise recommendations (TER) in sedentary obese men.Sixteen subjects [37.8 ± 5.8 years; body mass index (BMI) 32.8 4.7 kg/m(2)] were randomly allocated 2 weeks either SIT (6 sessions 8-12 × 10 s sprints) or TER [10 30 min at 65% peak oxygen consumption (VO(2peak))] cycle exercise. Fasting plasma glucose, insulin, non-esterified fatty acids (NEFA), homeostasis model assessment...

10.1111/dom.12150 article EN Diabetes Obesity and Metabolism 2013-06-26

The purpose of this study was to examine the effects vitamin E (VE) supplementation (1200 IU/day) on recovery responses repeated bouts resistance exercise. Non-resistance trained men were assigned supplement with VE (n = 9) or placebo (PL; n for 3 weeks and then perform exercise sessions separated by days (EX-1, EX-2, EX-3). Performance assessed at EX-1, EX-3. Fasting morning blood samples perceived muscle soreness obtained before EX-1 10 consecutive days. Muscle peaked after gradually...

10.1519/1533-4287(2003)017<0801:eoveso>2.0.co;2 article EN The Journal of Strength and Conditioning Research 2003-01-01

Purpose: The purpose of this investigation was to examine the influence resistance training on circulating concentrations growth hormone binding protein (GHBP) in response acute heavy exercise. Methods: Using a cross-sectional experimental design, group resistance-trained men (RT, N = 9, 7.9 ± 1.3 yr experience) and untrained (UT, 10) performed an exercise protocol (AHREP) consisting 6 sets 10 repetition maximum parallel squats. Blood samples were obtained 72 h before exercise, immediately...

10.1249/01.mss.0000155402.93987.c0 article EN Medicine & Science in Sports & Exercise 2005-03-01

The object of this study was to examine changes in muscular strength, power, and resting hormonal concentrations during 6 weeks detraining (DTR) recreationally strength-trained men. Each subject randomly assigned either a DTR (n = 9) or resistance training (RT; n 7) group after being matched for body size, experience. Muscular strength power testing, anthropometry, blood sampling were performed before the experimental period (T1), 3 (T2), 6-week (T3). One-repetition maximum (1RM) shoulder...

10.1519/1533-4287(2002)016<0373:dpmcip>2.0.co;2 article EN The Journal of Strength and Conditioning Research 2002-01-01
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