A5068261789- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Parasites and Host Interactions
- Parasitic Diseases Research and Treatment
- Insect symbiosis and bacterial influences
- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Insect Resistance and Genetics
- vaccines and immunoinformatics approaches
- Bacillus and Francisella bacterial research
- Insect and Pesticide Research
Nazi Boni University
2016-2022
Centre international de recherche-développement sur l'elevage en zone subhumide
2011-2019
Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle
2016
Agropolis International
2016
Institut de Recherche pour le Développement
2011
Centre de Coopération Internationale en Recherche Agronomique pour le Développement
2011
Background Control of gambiense sleeping sickness, a neglected tropical disease targeted for elimination by 2020, relies mainly on mass screening populations at risk and treatment cases. This strategy is however challenged the existence undetected reservoirs parasites that contribute to maintenance transmission. In this study, performed in Boffa focus Guinea, we evaluated value adding vector control medical surveys measured its impact burden. Methods The was divided into two parts (screen...
Individual rapid tests for serodiagnosis (RDT) of human African trypanosomiasis (HAT) are particularly suited passive screening and surveillance. However, so far, no large scale evaluation RDTs has been performed diagnosis Trypanosoma brucei gambiense HAT in West Africa. The objective this study was to assess the diagnostic accuracy 2 commercial HAT-RDTs on stored plasma samples from Africa.SD Bioline Sero-K-Set were 722 originating Guinea Côte d'Ivoire, including 231 parasitologically...
The analysis of humoral responses directed against the saliva blood-sucking arthropods was shown to provide epidemiological biomarkers human exposure vector-borne diseases. However, use whole as antigen presents several limitations such problems mass production, reproducibility and specificity. aim this study design a specific biomarker tsetse flies based on in silico three Glossina salivary proteins (Ada, Ag5 Tsgf1) previously be specifically recognized by plasma from exposed...
The World Health Organization (WHO) has set the goal of gambiense-Human African trypanosomiasis (HAT) elimination as a public health problem for 2020 and interruption transmission in humans 2030. In this context, it is crucial to monitor progress towards these targets using accurate tools assess level given area. aim study was investigate relevance immune trypanolysis test (TL) population-based bioassay evaluate Trypanosoma brucei gambiense various epidemiological contexts. Significant...
Burkina Faso belongs to a group of countries in which human African trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense, is no longer considered be public health problem. Although native cases have been detected since 1993, there still the risk HAT re-emergence due significant population movements between and active foci Côte d'Ivoire. Since 2014, receives support from WHO implement passive surveillance program. This resulted detection 2015 first putative case two decades. However,...
The saliva of tsetse flies contains a cocktail bioactive molecules inducing specific antibody responses in hosts exposed to bites. We have previously shown that an indirect-ELISA test using whole salivary extracts from Glossina morsitans submorsitans was able discriminate between (i) cattle infested and free areas (ii) animals experimentally low or high numbers flies. In the present study, our aim identify synthetic peptides could be used develop simple immunoassays measure exposure flies.In...
Background Continued post-elimination monitoring is required to ensure sustainability of zero transmission human African trypanosomosis (HAT) and avoid re-emergence caused by potential remaining Trypanosoma brucei gambiense reservoirs (animal and/or human). Until now, no tool able attest or validate elimination. Increasingly, the serological immune trypanolysis test being implemented in decision algorithms characterise parasitological unconfirmed CATT RDT seropositive subjects. Therefore, we...