A5054303774- Trypanosoma species research and implications
- Mosquito-borne diseases and control
- Parasites and Host Interactions
- Research on Leishmaniasis Studies
- Insect symbiosis and bacterial influences
- Parasitic Diseases Research and Treatment
- Agriculture and Rural Development Research
- Vector-borne infectious diseases
- African Studies and Ethnography
- Vector-Borne Animal Diseases
- Migration, Identity, and Health
- African Botany and Ecology Studies
- Zoonotic diseases and public health
- Tuberculosis Research and Epidemiology
- Evolution and Genetic Dynamics
- Neonatal Health and Biochemistry
- Virology and Viral Diseases
- Insect-Plant Interactions and Control
- African Studies and Geopolitics
- Pneumocystis jirovecii pneumonia detection and treatment
- Cocoa and Sweet Potato Agronomy
- Viral Infections and Vectors
- Yersinia bacterium, plague, ectoparasites research
- Oil Palm Production and Sustainability
- Blood disorders and treatments
Institut de Recherche pour le Développement
2011-2024
Institut de Recherche Pour le Développement
2014-2024
Université de Montpellier
2018-2023
Centre de Coopération Internationale en Recherche Agronomique pour le Développement
2010-2023
Institut National de Santé Publique
2019-2022
Institut de Recherche pour le Développement
2016-2020
Interactions hotes-vecteurs-parasites-environnement dans les maladies tropicales négligées dues aux trypanosomatides
2016-2020
Biologie et Génétique des Interactions Plante-Parasite
2019
Institut de Recherche pour le Développement
2018
Centre international de recherche-développement sur l'elevage en zone subhumide
2008-2016
Following World Health Assembly resolutions 50.36 in 1997 and 56.7 2003, the Organization (WHO) committed itself to supporting human African trypanosomiasis (HAT)-endemic countries their efforts remove disease as a public health problem. Mapping distribution of HAT time space has pivotal role play if this objective is be met. For reason WHO launched Atlas initiative, jointly implemented with Food Agriculture United Nations, framework Programme Against Trypanosomosis.The presented for 23 out...
Background Gambian sleeping sickness or HAT (human African trypanosomiasis) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted riverine species of tsetse. A global programme aims to eliminate the as public health problem 2020 and stop transmission 2030. In South Chad, Mandoul area persistent focus where around 100 cases were still diagnosed treated annually until 2013. Pre-2014, control relied solely on case detection treatment, which lead gradual decrease in...
Background Control of gambiense sleeping sickness, a neglected tropical disease targeted for elimination by 2020, relies mainly on mass screening populations at risk and treatment cases. This strategy is however challenged the existence undetected reservoirs parasites that contribute to maintenance transmission. In this study, performed in Boffa focus Guinea, we evaluated value adding vector control medical surveys measured its impact burden. Methods The was divided into two parts (screen...
Important control efforts have led to a significant reduction of the prevalence human African trypanosomiasis (HAT) in Côte d'Ivoire, but disease is still present several foci. The existence an animal reservoir Trypanosoma brucei gambiense may explain persistence these foci where breeding important source income (AAT) unknown. aim this study was identify trypanosome species circulating domestic animals both Bonon and Sinfra HAT endemic foci.552 (goats, pigs, cattle sheep) were included....
Human African trypanosomosis (HAT), also known as sleeping sickness, is still a major concern in endemic countries. Its cyclical vector are biting insects of the genus Glossina or tsetse flies. In Guinea, mangrove ecosystem contains main HAT foci Western Africa. There, palpalis gambiensis. A ongoing control campaign (VCC) started 2011 focus Boffa, using tiny targets, with 79% density reduction 2016 and significant impact on prevalence disease (from 0.3% to 0.11% 2013, 0.0352% 0.0097% 2019)....
Background Because of its high sensitivity and ease use in the field, card agglutination test for trypanosomiasis (CATT) is widely used mass screening sleeping sickness. However, CATT exhibits false-positive results (i) raising question whether CATT-positive subjects who are negative parasitology truly exposed to infection (ii) making it difficult evaluate Trypanosoma brucei (T.b.) gambiense still circulating areas low endemicity. The objective this study was assess value immune trypanolysis...
Gambiense human African trypanosomiasis (g-HAT) is the chronic form of sleeping sickness caused by Trypanosoma brucei gambiense in West and Central Africa, while rhodesiense causes an acute eastern Africa. g-HAT targeted for elimination as a public health problem 2020 0 transmission 2030 [1,2]. Control largely based on identification treatment infected individuals, supplemented control tsetse fly vectors [3]. There has been growing evidence that when both case activities are carried out...
Human African Trypanosomiasis (HAT) in West Africa is a lethal, neglected disease caused by Trypanosoma brucei gambiense transmitted the tsetse Glossina palpalis gambiensis. Although littoral part of Guinea with its typical mangrove habitat most prevalent area Africa, very few data are available on epidemiology such biotopes. As HAT elimination project Guinea, we carried cross-sectional study distribution and abundance people, livestock, trypanosomes focus Boffa. An exhaustive census human...
Abstract Background Since 2012, the World Health Organisation and countries affected by Gambian form of human African trypanosomiasis (HAT) have been committed to eliminating disease, primarily through active case-finding treatment. To interrupt transmission Trypanosoma brucei gambiense move more rapidly towards elimination, it was decided add vector control using ‘tiny targets’. Chad’s Mandoul HAT focus extends over 840 km 2 , with a population 39,000 as well 14,000 cattle 3000 pigs. Some...
Background Gambian human African trypanosomiasis (gHAT) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted tsetse flies ( Glossina ). In Côte d’Ivoire, Bonon the most important focus of gHAT, with 325 cases diagnosed from 2000 to 2015 and efforts against gHAT have relied largely on mass screening treatment cases. We assessed whether addition control deploying Tiny Targets offers benefit sole reliance screen-and-treat strategy. Methodology principal findings...
The northern distribution limit of tsetse flies was updated in Burkina Faso and compared to previous limits revise the existing map these vectors African trypanosomiases dating from several decades ago. From 1949 2009, a 25- 150-km shift has appeared toward south. Tsetse are now discontinuously distributed with western an eastern belt. This range can be explained by combination decreased rainfall increased human density. Within context international control, this study provides better...
Male and female tsetse flies feed exclusively on vertebrate blood. While doing so they can transmit the diseases of sleeping sickness in humans nagana domestic stock. Knowledge host-orientated behavior is important designing bait methods sampling controlling flies, understanding epidemiology diseases. For this we must explain several puzzling distinctions different sexes species tsetse. example, why it that occupying savannahs, unlike those riverine habitats, appear strongly responsive to...
Abstract Background The tsetse fly Glossina palpalis gambiensis is the main vector of sleeping sickness (Human African Trypanosomiasis - HAT) in West Africa, particular littoral Guinea where this disease currently very active. Loos islands constitute a small archipelago some 5 km from mainland Guinea, G. p. well known as nuisance and potential by inhabitants three islands, Fotoba, Room, Kassa. National Control Program against HAT has decided to eradicate order sustainably protect humans...
Significant efforts to control human African trypanosomiasis (HAT) over the three past decades have resulted in drastic reductions of disease prevalence Côte d'Ivoire. In this context, costly and labor-intensive active mass screening strategy is no longer efficient. addition a more cost-effective passive surveillance system being implemented low-prevalence our aim was develop an alternative targeted strategy. 2012, we carried out door-to-door (TDD) survey focused on immediate vicinities...
Background Human African trypanosomiasis is a parasitic disease caused by trypanosomes among which Trypanosoma brucei gambiense responsible for chronic form (gHAT) in West and Central Africa. Its elimination as public health problem (EPHP) was targeted 2020. Côte d’Ivoire one of the first countries to be validated WHO 2020 this particularly challenging country still reported around hundred cases year early 2000s. This article describes strategies implemented including mathematical model...
Entomological and phyto-sociological surveys were undertaken in Folonzo, southern Burkina Faso, along the Comoé river. The purpose of this survey was to compare densities diversity tsetse species a protected versus non area, by mean transects going from river bank savannah. A detailed phytological description made all trapping sites. entomological data also compared what obtained 1980 same phytogeographical study showed great vegetation homogeneity between transects, particularly forest...
Human population growth, climate change and economic development are causing major environmental modifications in Western Africa, which will have important repercussions on the epidemiology of sleeping sickness. A new initiative, Atlas human African trypanosomiasis (HAT), aims at assembling geo-referencing all epidemiological data derived from both active screening activities passive surveillance. geographic database enables to generate up-to-date disease maps a range scales unprecedented...
Objectives To provide a better understanding of sleeping sickness transmission and spread in mangrove areas to optimize its control. Methods In the Forecariah area, Guinea, 19 cases matched controls were followed up their living (at home, fields at water points). All occupational sites pathways mapped then placed environmental context. Results The displayed significantly broader more diverse spatial occupation than controls. They covered double daily walking distances had on average two...
Abstract In addition to the thousands of deaths due unprecedented ebola outbreak that stroke West Africa (2014-2016), national health systems in affected countries were deeply challenged impacting a number diseases control programs. Here we describe case Human African Trypanosomiasis (HAT), deadly neglected tropical disease trypanosome transmitted by tsetse flies for which no vaccine nor chemoprophylaxis exists. Data are presented focus Boffa Guinea where pilot elimination project combining...
Human African trypanosomiasis (HAT) is a vector-borne parasitic disease which has often been considered rural disease. Population increases in countries have entailed the spread of urban centres, creating favourable conditions for appearance new epidemiological conditions. In Cote d'Ivoire, HAT transmission described surroundings towns such as Daloa or Sinfra. focus Bonon, located central-western medical survey detected 96 patients. The sites visited by patients every day were geo-referenced...
This study aimed at identifying factors influencing the development of Human African Trypanosomosis (HAT, or sleeping sickness) in focus Bonon, located mesophile forest Côte d'Ivoire. A previous mapping main daytime activity sites 96 patients revealed an important disparity between area south town- where all lived- and north town, apparently free disease. In order to explain this disparity, we carried out a spatial analysis key components pathogenic system, i.e. human host, tsetse vector...