A5056887555- Trypanosoma species research and implications
- Mosquito-borne diseases and control
- Insect symbiosis and bacterial influences
- Vector-Borne Animal Diseases
- Vector-borne infectious diseases
- Ecology and Vegetation Dynamics Studies
- Parasitic Diseases Research and Treatment
- Viral Infections and Vectors
- Parasites and Host Interactions
- Cell Image Analysis Techniques
- Machine Learning and Data Classification
- HIV/AIDS Research and Interventions
- Artificial Intelligence in Healthcare
- Anomaly Detection Techniques and Applications
- Genetics, Bioinformatics, and Biomedical Research
- Imbalanced Data Classification Techniques
- HIV/AIDS drug development and treatment
- Virology and Viral Diseases
- Research on Leishmaniasis Studies
- ICT in Developing Communities
- Insect-Plant Interactions and Control
Coordinating Office for Control of Trypanosomiasis in Uganda
2015-2024
Ministry of Agriculture, Animal Industry and Fisheries
2017-2022
University of Edinburgh
2015-2021
Edinburgh College
2016
Ticks and tick-borne diseases undermine cattle fitness productivity in the whole of sub-Saharan Africa, including Nigeria. In this West African country, are challenged by numerous tick species, especially during wet season. Consequently, several TBDs known to be endemic Nigerian cattle, anaplasmosis, babesiosis, cowdriosis theilerioris (by Theileria mutans velifera). To date, all investigations on Nigeria have been based cytological examinations and/or serological methods. This study aimed...
Nagana (African Animal Trypanosomiasis-AAT) and tick-borne diseases (TBDs) constrain livestock production in most parts of sub-Saharan Africa. To this realisation, Uganda government set up an African trypanosomiasis (AT) control unit, which among other activities generates national tsetse priority maps using apparent density data. Such underestimate mechanically transmitted AAT thus ought to be refined actual AT prevalence We therefore out generate up-to-date cattle donkey data as well find...
Gambiense human African trypanosomiasis (g-HAT) is the chronic form of sleeping sickness caused by Trypanosoma brucei gambiense in West and Central Africa, while rhodesiense causes an acute eastern Africa. g-HAT targeted for elimination as a public health problem 2020 0 transmission 2030 [1,2]. Control largely based on identification treatment infected individuals, supplemented control tsetse fly vectors [3]. There has been growing evidence that when both case activities are carried out...
Tsetse flies transmit trypanosomes, the causative agent of human and animal African trypanosomiasis. The tsetse vector is extensively distributed across sub-Saharan Africa. Trypanosomiasis maintenance determined by interrelationship three elements: vertebrate host, parasite responsible for transmission. Mapping distribution abundance assists in predicting trypanosomiasis distributions developing rational strategies disease control. Given scarce resources to carry out regular full scale field...
In 1994, combined active and passive screening reported 1469 cases from the historic Gambian Human African Trypanosomiasis (gHAT) foci of West Nile, Uganda. Since 2011 systematic has stopped there been reliance on screening. During 2014, alone detected just nine cases. same year a tsetse control intervention was expanded to cover main gHAT in Nile curtail transmission contributing elimination as public health problem area. It is known that sole slow detect can underestimate actual true...
Background Tsetse flies ( Glossina ) transmit Trypanosoma brucei gambiense which causes Gambian human African trypanosomiasis (gHAT) in Central and West Africa. Several countries use Tiny Targets, comprising insecticide-treated panels of material attract kill tsetse, as part their national programmes to eliminate gHAT. We studied how the scale arrangement target deployment affected efficacy control. Methodology principal findings Between 2012 2016, Targets were deployed biannually along...
Abstract Background Riverine species of tsetse ( Glossina ) transmit Trypanosoma brucei gambiense , which causes Gambian human African trypanosomiasis (gHAT), a neglected tropical disease. Uganda aims to eliminate gHAT as public health problem through detection and treatment cases vector control. The latter is being achieved the deployment ‘Tiny Targets’, insecticide-impregnated panels material attract kill tsetse. We analysed spatial temporal distribution in during period 2010–2019 assess...
Background Tsetse flies are the major vectors of human trypanosomiasis form Trypanosoma brucei rhodesiense and T.b.gambiense. They widely spread across sub-Saharan Africa rendering a lot challenges to both animal health. This stresses effective agricultural production productivity in Africa. Delimiting extent magnitude tsetse coverage has been challenge over decades due limited resources unsatisfactory technology. In bid overcome these limitations, this study attempted explore modelling...
Improvements in genetic and genomic technology have enabled field-deployable molecular laboratories these been deployed a variety of epidemics that capture headlines. In this editorial, we highlight the importance building physical personnel capacity low middle income countries to deploy technologies improve diagnostics, understand transmission dynamics provide feedback endemic communities on actionable timelines. We describe our experiences with field research schistosomiasis,...
Introduction: Trypanosomiasis is a parasitic infection caused by the protozoa Trypanosoma. It exclusively associated with Glossina species habitats and, therefore, restricted to specific geographical settings. affects wide range of hosts, including humans. Animals may carry different Trypanosoma spp. while being asymptomatic. They are, potentially important in unpremeditated disease transmission. Aim: The aim this study was potential impact government tsetse fly control program, and...
Abstract Introduction Tsetse flies ( Glossina ) transmit Trypanosoma brucei gambiense which causes human African trypanosomiasis (gHAT). As part of national efforts to eliminate gHAT as a public health problem, Uganda implemented large-scale programme deploying Tiny Targets, comprise panels insecticide-treated material attract and kill tsetse. At its peak, the was largest tsetse control operation in Africa. Here, we quantify impact Targets environmental changes on spatial temporal patterns...
Tsetse flies (
Treatment of sleeping sickness and nagana is threatened by drug resistance. To guide use in control, we set out to determine if cattle-derived resistant causing parasites spill-over humans as resistant; treatment failure. We screened cattle (n= 2,750) patients (n=147) from south-eastern Uganda for [T. b. rhodesiense]] [ T. brucei s.l. ] hence determined their prevalence either populations using sound statistical means. One three [949/2,750] was positive about 90 every 100 these had changes...
Abstract Background Riverine species of tsetse ( Glossina ) transmit Trypanosoma brucei gambiense which causes Gambian human African trypanosomiasis (gHAT), a neglected tropical disease. Uganda aims to eliminate gHAT as public health problem through detection and treatment cases vector control. The latter is being achieved the deployment ‘Tiny Targets’, insecticide-impregnated panels material attract kill tsetse. We analysed spatial temporal distribution in during period 2010-2019 assess...