A5072134739- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Multiple Myeloma Research and Treatments
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Hepatitis C virus research
- Chronic Myeloid Leukemia Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Fullerene Chemistry and Applications
- Cancer survivorship and care
- Glycosylation and Glycoproteins Research
- Eosinophilic Disorders and Syndromes
- Retinoids in leukemia and cellular processes
- Platelet Disorders and Treatments
- Hepatitis B Virus Studies
- Blood groups and transfusion
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Bone health and treatments
- Gastric Cancer Management and Outcomes
- Endometrial and Cervical Cancer Treatments
- Analytical Chemistry and Chromatography
- Protein Degradation and Inhibitors
- Colorectal and Anal Carcinomas
- Kruppel-like factors research
Chang Bing Show Chwan Memorial Hospital
2020-2024
Central Taiwan University of Science and Technology
2023
Changhua Christian Hospital
2009-2022
National Taiwan University Hospital
1991-2007
R.O.C Military Academy
1998
Seven relapsed and/or refractory acute promyelocytic leukaemia patients were treated by arsenic trioxide (As 2 O 3 ). Four (4/7, 57%) achieved complete remission after one to three cycles of treatment and the most common side‐effect was fluid retention (in six patients, 86%), including weight gains pleuro‐pericardial effusions. Evident polyneuropathy compatible with chronic toxicity noted in two who received As maintenance therapy them had marked distal muscular atrophy. We suggest that may...
Empirical studies of the relationship between posttraumatic growth (PTG) and adjustment outcomes reveal a fairly inconclusive picture. We argue that inconsistent findings are likely due to heterogeneity PTG experience over time. In this regard, we predicted individuals with different trajectories vary in level correlational patterns adjustment.Participants were 124 Taiwanese women who underwent surgery for breast cancer. Measures variables, including positive affect, negative mental physical...
Abstract Background Cancer is one of the major health issues worldwide. An increasing number cancer patients are offered treatment with surgery, chemotherapy and radiotherapy. Traditional Chinese medicine (TCM) most common complementary therapies to in Taiwan. We designed a randomized, double-blind, placebo-controlled clinical trial evaluate efficacy TCM cancer. Methods/design In this study, inclusion criteria postoperative histologically confirmed within 3 years who undergoing or...
Abstract Objective Early‐stage breast cancer patients generally receive either a mastectomy or lumpectomy, by their own choice that of surgeon. Sometimes, there is regret about the decision afterward. To better understand surgical decisions, this study examined 2 possibilities: The first women who take dominant collaborative role in making surgery express less second congruence between preferred and actual predicts regret. We also explored whether disease stage moderates relationship...
Abstract Aim To evaluate the prevalence of pain in cancer outpatients Taiwan and to investigate impact on quality life (QoL) patient satisfaction. Results were compared those a similarly designed study conducted 2008 identify trends. Methods Adult patients with treated as hospitals throughout recruited. Pain intensity extent which interfered QoL self‐reported using modified version Brief Inventory. Patients also indicated their level satisfaction physician, well control. A total 2652...
Hepatitis B virus (HBV) reactivation may occur spontaneously, during or after antiviral therapy, when receiving immunosuppressive chemotherapy. HBV has also been reported in cancer patients targeted therapies, such as monoclonal antibody and mammalian target of rapamycin (mTOR) inhibitor. This review article is aimed to discuss the issue regarding chronic with a special focus on tyrosine kinase inhibitors.Using MEDLINE search, literature relevant hepatitis reactivation, therapy inhibitor was...
The primary analysis of a global phase 3 study that evaluated the efficacy and safety denosumab versus zoledronic acid for preventing skeletal-related events (SREs) in adults with newly diagnosed multiple myeloma (MM) indicated was noninferior to time first on-study SREs. Here we present subgroup evaluate Asian patients. Patients were randomized 1:1 receive 120 mg subcutaneously or intravenously 4 every weeks double-blind, double-dummy fashion. All patients received standard-of-care...
<i>Background:</i> Extrapulmonary small cell carcinoma (EPSCC) is a heterogeneous group of cancers. The clinicopathological features EPSCC remain poorly defined. <i>Patients and Methods:</i> Patients with the EPSCC, treated at three major medical centers in Taiwan, were included. Histologic clinical diagnoses, smoking history, staging, course treatment outcome reviewed analyzed. <i>Results:</i> A total 90 patients, between 1995 2005, eligible for analysis....
Accurate diagnostic assessment of human epidermal growth factor receptor-2 (HER-2) is essential and a prerequisite for appropriate application the humanized anti-HER-2 monoclonal antibody trastuzumab (Herceptin) to treatment patients with breast cancer. Immunohistochemistry (IHC) most widely applicable modality in studying HER-2 status. Fluorescence situ hybridization (FISH) also recognized as cases an equivocal IHC status (score, 2+). Some authors claimed that FISH alone sufficient. The aim...
Heritable thrombophilias are assumed important etiologies for recurrent pregnancy loss. Unlike in the Caucasian populations, protein S and C deficiencies, instead of Factor V Lieden Prothrombin mutations, relatively common Han Chinese population. In this study we aimed to investigate therapeutic effect low molecular weight heparin upon women with loss documented deficiency. During 2011–2016, 68 (RPL) deficiency (both free antigen function were reduced) initially enrolled. All must have...
Pure red cell aplasia (PRCA) is a rare hematological disorder which characterized by severe anemia, reticulocytopenia and almost complete absence of erythroid precursors in bone marrow.The pathophysiology PRCA may be congenital or acquired.To our knowledge, there only one case report the English literature after pegylated interferon combination therapy for chronic hepatitis C. We second treatment The diagnosis was confirmed typical findings marrow biopsy.The possible etiologies are also...
Background: Nilotinib, a second-generation tyrosine kinase inhibitor (TKI), is approved for the treatment of patients with chronic myeloid leukemia (CML) in many countries, including Taiwan. Though number controlled clinical trials have demonstrated safety and efficacy nilotinib, studies assessing nilotinib routine practice are limited. Methods: The current study was an open-label, single-arm conducted across 12 centers Taiwan adult CML or accelerated phase confirmed Ph+ chromosome (or...
To investigate the effects of different hospital patient loads on standard care and treatment outcomes patients with cervical cancer treated primarily radiation therapy to identify factors that may contribute survival differences among hospitals.We used Taiwan Cancer Registry database extract data a total 2582 International Federation Gynecology Obstetrics stage IB IVA uterine diagnosed from 2007 2013 who underwent curative (with or without chemotherapy). We explored associations loads,...
Background: Although both chemotherapy and radiotherapy (RT) can sufficiently maintain tumor suppression of colorectal cancer (CRC), these treatments may trigger the expression nuclear factor kappa B (NF-κB) compromise patients9 survival. Regorafenib suppresses NF-κB activity in various types. However, whether regorafenib act as a suitable radiosensitizer to enhance therapeutic efficacy RT remains unknown. Materials Methods: Here, we established CRC-bearing animal model investigate...
Purpose: Bone marrow metastasis of cancer is a sign extensively hematogenous spreading and may be terminal event those patients. With the improvement systemic chemotherapy for malignant disease, some patients have longer survival. We plan to find out clinical hematologic presentation prognostic factors in with bone metastasis. Materials & Methods: In this retrospective study, we reviewed results 162 examination carried adult malignancy (colon, lung, gastric, breast prostate cancers)...
Abstract Background and Purpose Prior research has debated whether reflective pondering is a more constructive form of rumination than brooding, which generally considered maladaptive. This study sought to investigate predicts depressive symptoms adaptive under certain conditions. We predicted that the effectiveness could depend on concurrent coping strategies trait–state distinction. Method Women with breast cancer (N = 309; M age 47.5) were assessed at four waves over 2 years. A...
Idiopathic or immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by low platelet count resulting from antibody-mediated destruction of platelets. The production these IgG anti-platelet autoantibodies critically governed T-lymphocytes which can be activated antigen-presenting cells (APC) such as dendritic cells. We hypothesized that one the mechanisms corticosteroid administration suppress system to depress number circulating in ITP patients. Dendritic cell...