Xiaochen Chen

ORCID: 0000-0003-1017-2773
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About
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Research Areas
  • Nanocomposite Films for Food Packaging
  • Electrospun Nanofibers in Biomedical Applications
  • CAR-T cell therapy research
  • Essential Oils and Antimicrobial Activity
  • Advanced Drug Delivery Systems
  • Seaweed-derived Bioactive Compounds
  • Algal biology and biofuel production
  • Advanced Nanomaterials in Catalysis
  • Meat and Animal Product Quality
  • Probiotics and Fermented Foods
  • biodegradable polymer synthesis and properties
  • Advanced Photocatalysis Techniques
  • Lymphoma Diagnosis and Treatment
  • Advanced Chemical Sensor Technologies
  • Bacterial biofilms and quorum sensing
  • Protein Hydrolysis and Bioactive Peptides
  • Bacteriophages and microbial interactions
  • Bee Products Chemical Analysis
  • 3D Printing in Biomedical Research
  • Conducting polymers and applications
  • Carbon and Quantum Dots Applications
  • Microencapsulation and Drying Processes
  • Salmonella and Campylobacter epidemiology
  • Chronic Lymphocytic Leukemia Research
  • Enzyme Catalysis and Immobilization

Tongji University
2025

Zhejiang Provincial People's Hospital
2025

Hangzhou Medical College
2025

Fuzhou University
2025

Jiangsu University
2021-2024

Jimei University
2023-2024

Shanghai Maritime University
2023

Soochow University
2019-2021

First Affiliated Hospital of Soochow University
2019-2021

State Administration of Traditional Chinese Medicine of the People's Republic of China
2021

In this study, we have demonstrates that nitrogen-plasma-treated g-C<sub>3</sub>N<sub>4</sub> nanosheet exhibits excellent and broad-spectrum antibacterial activity against eight foodborne pathogens in the absence of light illumination.

10.1039/c9nr03797g article EN Nanoscale 2019-01-01

Plant phloem-based defence (PBD) against phloem-feeding insects is characteristic of the sieve occlusion by phloem lectins and β-1,3-glucan callose, both which are produced under regulation ethylene MYB transcription factors. Wheat PBD requires synthase-like proteins GSL2, GSL10, GSL12, may also require insect-resistant mannose-binding Hfr-1 Wci-1, can accumulate in upon aphid feeding. This study elucidates whether any 73 genes identified previously common wheat Triticum aestivum genome...

10.1093/jxb/erx204 article EN Journal of Experimental Botany 2017-06-14

Background The use of T cells expressing chimeric antigen receptor (CAR T) engineered to target CD19 constitutes breakthrough treatment for relapsed or refractory B cell non-Hodgkin lymphoma (R/R B-NHL). Despite improved outcomes, high relapse rate remains a challenge overcome. Here, we report the clinical results and pharmacokinetics bispecific CD19/22 CAR in patients with R/R B-NHL. Methods We performed prospective, single-arm study analyzed safety efficacy investigated kinetic profiles...

10.3389/fonc.2021.664421 article EN cc-by Frontiers in Oncology 2021-05-25

In order to prevent food-borne diseases caused by Listeria monocytogenes (L. monocytogenes) safely and effectively, plant essential oils that have no toxic side effects are not prone drug resistance become the focus of research. This article takes basil (Ocimum basilicum L.) oil (BEO) as research object explores its antibacterial mechanism against L. monocytogenes. The site action was preliminarily determined provide a theoretical basis for development natural agents. results show BEO has...

10.3389/fmicb.2022.855905 article EN cc-by Frontiers in Microbiology 2022-04-01

Cinnamaldehyde (CA) possesses high antibacterial activity, but it's unstable and volatile in food system. To overcome its drawbacks, a kind of dual-response controlled-release nanofiber was fabricated by electrospinning to embed [email protected] acid/carboxymethyl chitosan nanoparticles ([email protected]/CMCS-NPs) into silk fibroin nanofibers protected]/CMCS-NPs SF nanofibers). When the concentration 5 mg/mL, have better mechanical properties, tensile strength 3.21 MPa, elongation at break...

10.1016/j.lwt.2021.112606 article EN cc-by-nc-nd LWT 2021-10-11

Edible nanoparticles containing antibacterial agents are one of the effective strategies to control foodborne diseases. Herein, novel ternary (TNP) were prepared from rosemary essential oil (REO), nisin and Lycium barbarum polysaccharides (LBP) through hydrophobic electrostatic interaction. The average particle size TNP was 211.5 nm, its encapsulation efficiency reached 86.6%. After addition LBP, physical stability, thermal stability storage significantly improved. In vitro, compared with...

10.3390/foods11030438 article EN cc-by Foods 2022-02-02

Direct pulp capping is crucial for maintaining dental vitality. The materials employed this purpose should possess properties such as easy-handling, excellent biocompatibility, infection resistance, and the ability to stimulate formation of reparative dentin. Mineral trioxide aggregate (MTA) commonly used capping. However, certain limitations, including its long setting time, insufficient anti-washout ability, high initial curing pH, handling difficulties, restrict MTA from meeting a broader...

10.1088/1748-605x/adb119 article EN Biomedical Materials 2025-01-31

Photosynthetic pigments such as phycobiliproteins and chlorophyll a are important quality indicators of seaweeds. In this study, multivariate nonlinear regression (MNLR) models were developed validated for the rapid determination photosynthetic in Porphyra haitanensis based on colorimetric parameters (L*, a*, b*). The contents phycoerythrin, phycocyanin, allophycocyanin P. within 1.499–8.882 mg/g, 1.402–7.634 0.315–1.623 0.340–2.160 respectively. L*, b* values 13.47–32.97, −1.88 to 2.74,...

10.3389/fsufs.2025.1553250 article EN cc-by Frontiers in Sustainable Food Systems 2025-02-18

Surufatinib is a novel, China-developed small-molecule tyrosine kinase inhibitor that demonstrates high selectivity for VEGFR, FGFR1, and CSF1R. has been approved the treatment of neuroendcrine tumors, including pancreatic neuroendocrine tumors (PNEN) non-pancreatic (N-pNEN). The purpose this retrospective study to assess Surufatinib's safety effectiveness in patients with various advanced solid malignancies. general clinical statistics follow-up data treated at Zhejiang Provincial People's...

10.1038/s41598-025-00974-8 article EN cc-by-nc-nd Scientific Reports 2025-05-10
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