A5053262521- Immunodeficiency and Autoimmune Disorders
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Public Health and Environmental Issues
- Streptococcal Infections and Treatments
- Kawasaki Disease and Coronary Complications
- Immune Cell Function and Interaction
- Antifungal resistance and susceptibility
- Autoimmune and Inflammatory Disorders Research
- Neutropenia and Cancer Infections
- Parvovirus B19 Infection Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Neonatal Health and Biochemistry
- Bacterial Infections and Vaccines
- Hematopoietic Stem Cell Transplantation
- Fungal Infections and Studies
- Cytomegalovirus and herpesvirus research
- Tracheal and airway disorders
- Polyomavirus and related diseases
- HIV/AIDS oral health manifestations
- Liver Disease and Transplantation
- Chronic Lymphocytic Leukemia Research
- Infectious Encephalopathies and Encephalitis
- Developmental and Educational Neuropsychology
- Erythrocyte Function and Pathophysiology
Fundación Valle del Lili
2018-2025
Icesi University
2018-2025
Fundación Neumológica Colombiana
2017
Asociación Colombiana de Infectología
2015-2017
Fundación Universitaria Sanitas
2013
Limited data is available from low-middle and upper-middle income countries of the factors associated with hospitalization or admission to pediatric intensive care unit (PICU) for children COVID-19.To describe PICU COVID-19 in Latin America.Multicenter, analytical, retrospective study reported 10 different American Latin-American Society Pediatric Infectious Diseases (SLIPE-COVID) research network June 1, 2020, February 28, 2021. Outpatient hospitalized <18 years age confirmed by polymerase...
Introduction Invasive Pneumococcal Disease (IPD) causes significant morbidity and mortality in children under 5 y. Colombia introduced PCV10 vaccination 2012, the Neumocolombia network has been monitoring IPD pediatric patients since 2008. Materials methods This study is a secondary analysis of prospective cohort involving with admitted to 17 hospitals Colombia, from January 1st, 2017, December 31st, 2022. We present data on serotypes (Spn), clinical characteristics, resistance patterns....
Introducción. Las especies de Candida son el principal agente etiológico infecciones fúngicas en la población pediátrica, especialmente neonatos y pacientes atendidos unidad cuidados intensivos. La candidiasis invasiva se relaciona con desenlaces clínicos desfavorables como tiempo hospitalización prolongado mortalidad.Objetivo. Describir las características demográficas, clínicas microbiológicas los pediátricos (mayores un mes menores 18 años) hospitalizados una intensivos diagnóstico...
Introduction: With the use of pneumococcal conjugate vaccines(PCV), behavior invasive disease(IPD) has changed relative to serotype distribution. The introduction these vaccines in national immunization programs reduced incidence IPD, with a marked decrease circulation serotypes included vaccine used each country. However, subsequent emergence other not vaccine, such 19A case PCV7 and PCV10, been documented.Materials methods: This was series study (2008–2017) pediatric patients admitted 10...
This study aimed to describe the incidence, microbiological profile, and risk factors associated with bacteremia in pediatric patients hematopoietic stem cell transplantation (HSCT).
ObjectivesTo describe the clinical presentation, management, and outcomes of Kawasaki disease (KD) in Latin America to evaluate early prognostic indicators coronary artery aneurysm (CAA).Study designAn observational KD registry-based study was conducted 64 participating pediatric centers across 19 American countries retrospectively between January 1, 2009, December 31, 2013, prospectively from June 2014, May 2017. Demographic initial laboratory data were collected. Logistic regression...
Abstract Background Hemophagocytic lymphohistiocytosis (HLH) is an exaggerated inflammatory reaction secondary to a host’s inadequate immune response causing self-perpetuating loop of altered regulation. Signs and symptoms HLH are compatible with other common diseases nonspecific. Underdiagnosis makes it difficult estimate the real incidence HLH, especially in developing countries. Methods Retrospective, descriptive study pediatric patients admitted high-complexity institution Cali, Colombia...
Introduction Acute bacterial meningitis (ABM) is a public health problem. The disease has reemerged after the introduction of pneumococcal conjugate vaccines (PCVs) due to an increase in serotypes that are not covered. objective was determine changes incidence before and 10-valent vaccine (PCV10) Colombia. Methods This multicenter study conducted 17 hospitals Data were collected from January 2008 December 2019 10 Bogotá 2017 seven Cali, Medellín Cartagena. data grouped into three periods:...
Streptococcus pneumoniae causes meningitis, pneumonia and bacteremia, mainly in children under 5 years of age the elderly. Pneumococcal conjugate vaccines (PCVs) have been administered globally since year 2000, contributing to substantially reduce incidence pneumococcal diseases (PDs). In 2012, Colombia implemented universal vaccination with PCV10 2 age, achieving a decrease stabilization PDs. However, 2014, replacement vaccine serotypes by non-vaccine serotypes, such as 3 19A,...
Streptococcus pneumoniae (S. pneumoniae), also known as pneumococcus, is one of the main bacteria associated with mortality in children under 2 years age, a morbidity and incidence that varies according to demographics exposure risk, or protective factors.To describe child due invasive pneumococcal disease (IPD) between 2008 -2014 (6 years), 8 Medical Centres Bogotá, Colombia.Descriptive observational case series patients who died IPD, aged 28 days 18 years, tertiary care institutions...
The current literature describes the characteristics of some skin manifestations in context primary immunodeficiency diseases (PIDs), also known as inborn errors immune system. However, there are hardly any data on epidemiological trends and PIDs Latin America (LA). We aimed to describe patients with diagnosis a PID treated at tertiary hospital Colombia.This was retrospective observational study. Data were taken from institutional database pediatric PIDs, which includes 306 under 18 years...
Trends in distribution of S. pneumoniae capsular serotypes are associated with the introduction pneumococcal conjugate vaccines (PCV) among population. In Colombia, 10-valent PCV (PCV10) has been included national vaccination program since 2011. As a part surveillance network (SIREVA), Colombia gathered data serotype 1993. The aim this work is to determine effect PCV10 on non-coverage by specifically, 6A, 19A and 3 serotypes. Information was obtained from 1993 2016 children under 5 years....
Antifungal prophylaxis is recommended for hematopoietic stem cell transplantation (HSCT) to decrease the incidence of invasive fungal infections (IFI). This study aimed compare two groups antifungal in pediatric patients undergoing allogeneic HSCT.This observational, analytic, retrospective cohort compared IFI with voriconazole vs. other antifungals first 100 days after HSCT aged <18 years between 2012 and 2018. The statistical analysis included univariate multivariate analyses determination...
To describe a cohort of pediatric patients with encephalitis and their risk factors for admission to the intensive care unit (PICU).Children (<18 years old), evaluated by conventional microbiology syndromic, multiplex test in cerebrospinal fluid (CSF) between July 2017 2020, were recruited from 14 hospitals that comprise Colombian Network Encephalitis Pediatrics. Multivariate analyses used evaluate associated need PICU admission.Two hundred two children included, which 134 (66.3%) male. The...
In recent decades, there has been a growing increase in the diagnosis of patients with inborn errors immune system, formerly known as primary immunodeficiency disorders (PIDs). Timely remains challenge due to low clinical suspicion and poor education on subject. It is estimated that between 70% 90% these pathologies remain underdiagnosed our environment.The objective this study characterize demographic presentation pediatric group system Colombian tertiary hospital.Retrospective descriptive...
Abstract Background Cytomegalovirus infection represents a significant cause of morbidity and mortality after hematopoietic stem cell transplantation. This study aimed to evaluate the incidence viremia disease due cytomegalovirus risk factors in pediatric patients with transplantation our institution. Methods was retrospective cohort under 19 years age who underwent allogeneic any indication between 2012 2019. The analysis included diagnosis or during post‐transplant follow‐up, evaluation...
In pediatric patients undergoing liver transplantation, infections are one of the primary complications. The etiology varies depending on time elapsed post-transplant, with early presentations bacterial and fungal infections, followed by viral parasitic infections. There is limited literature describing prevalence infectious complications in this group Colombia. To describe transplantation within first 3 months post-procedure at Fundación Valle del Lili, Cali, A case series 165 transplant...
Objective: Community-acquired pneumonia (CAP) is one of the leading causes mortality in pediatric population. It often leads to hospitalization, with children under 1-year-old being most affected and usually requiring management intensive care unit. Recent molecular studies indicate that viruses are common etiology. The aim our study was characterize population severe CAP a high complexity center Cali, Colombia, describing demographics, etiologic factors, clinical evolution outcomes...
Introduction. Inborn errors of immunity are frequently associated with bronchiectasis. The diagnostic performance these inborn has improved because the association some entities progressive airway damage is better known. This knowledge allowed recognition and appropriate intervention reducing deterioration pulmonary function improving quality life. Objective. To describe a group patients bronchiectasis not related to cystic fibrosis who were diagnosed have been studied in an immunology...
Introduction. Hemophagocytic syndrome is an under-recognized condition with high mortality in the pediatric population. It characterized by excessive activation of immune cells and cytokine release, leading to persistent inflammation. can be primary or secondary associated different triggers. Objective. To describe 12 clinical cases children under five years age hemophagocytic a high-complexity institution southwestern Colombia. Materials methods. We present retrospective series treated at...