Bertrand Drugeon

ORCID: 0000-0003-1026-7975
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About
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Research Areas
  • Central Venous Catheters and Hemodialysis
  • Hemodynamic Monitoring and Therapy
  • Anesthesia and Pain Management
  • Antibiotics Pharmacokinetics and Efficacy
  • Diagnosis and Treatment of Venous Diseases
  • Patient Safety and Medication Errors
  • Optical Imaging and Spectroscopy Techniques
  • Infection Control in Healthcare
  • Trauma and Emergency Care Studies
  • Pressure Ulcer Prevention and Management
  • Ocular and Laser Science Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Blood transfusion and management
  • Hemoglobinopathies and Related Disorders
  • Health Systems, Economic Evaluations, Quality of Life
  • Vascular Procedures and Complications
  • Airway Management and Intubation Techniques
  • Diabetic Foot Ulcer Assessment and Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Streptococcal Infections and Treatments
  • Metabolism and Genetic Disorders
  • Erythropoietin and Anemia Treatment
  • Cardiac Arrest and Resuscitation
  • Chemotherapy-related skin toxicity
  • Child Abuse and Related Trauma

Université de Poitiers
2018-2025

Centre Hospitalier Universitaire de Poitiers
2018-2025

Inserm
2020-2025

Griffith University
2024-2025

Introduction Short peripheral intravenous catheters (PVCs) are the most frequently used invasive medical devices in hospitals. Unfortunately, PVCs often fail before end of treatment due to occurrence mechanical, vascular or infectious complications, which prolongs hospitalisation and increases healthcare costs mortality. Prevention these complications is mainly based on respect hygiene rules use biocompatible catheters. In critically ill patients, 2% chlorhexidine-alcohol superior 5%...

10.1136/bmjopen-2018-028549 article EN cc-by-nc BMJ Open 2019-04-01

The objective of the study was to perform a cost-effectiveness analysis bundled devices (BDs) versus standard (SDs) for prevention unscheduled peripheral venous catheter (PVC) removal due complication from French investigator-initiated, open-label, single center, randomized-controlled, two-by-two factorial trial (CLEAN-3 study). A 14-day time non homogeneous semi-markovian model performed be fitted longitudinal individual patient data CLEAN-3 database. This includes five health states and...

10.1371/journal.pone.0269750 article EN cc-by PLoS ONE 2022-06-14

Blood transfusion and anaemia are frequent associated with poor outcomes in patients hip fracture (HF). We hypothesised that preoperative intravenous iron tranexamic acid (TXA) may reduce the rate these patients. The HiFIT study is a multicentre, 2×2 factorial, randomised, double-blinded, controlled trial evaluating effect of isomaltoside (IIM) (20 mg/kg) vs placebo TXA (intravenously at inclusion topically during surgery) versus on hospitalisation, undergoing emergency surgery for HF having...

10.1136/bmjopen-2020-040273 article EN cc-by-nc BMJ Open 2021-01-01

Few data are available on the efficacy of 0.5% aqueous sodium hypochlorite (SH) for skin disinfection before peripheral catheter insertion. A total 239 patients were randomly assigned to either one application SH alone or preceded by 70% ethanol (ET-SH). Catheter colonization, defined as a tip culture growing >1000 cfu micro-organism per millilitre, occurred in 29 (33% 89 colonizations 1000 catheter-days) group and 31 126 ET-SH group.

10.1016/j.jhin.2021.11.012 article EN cc-by Journal of Hospital Infection 2021-11-23

Abstract Aim: Although uncommon, infections associated with peripheral intravenous catheters (PIVCs) may be responsible for severe life-threatening complications and increase healthcare costs. Few data are available on the relationship between PIVC insertion site risk of infectious complications. Methods: We performed a post hoc analysis CLEAN 3 database, randomised 2x2 factorial study comparing two skin disinfection procedures (2% chlorhexidine-alcohol or 5% povidone iodine-alcohol) types...

10.21203/rs.3.rs-4089476/v1 preprint EN cc-by Research Square (Research Square) 2024-03-15

Abstract Aim Although uncommon, infections associated with peripheral intravenous catheters (PIVCs) may be responsible for severe life-threatening complications and increase healthcare costs. Few data are available on the relationship between PIVC insertion site risk of infectious complications. Methods We performed a post hoc analysis CLEAN 3 database, randomized 2 × factorial study comparing two skin disinfection procedures (2% chlorhexidine-alcohol or 5% povidone iodine-alcohol) types...

10.1186/s13756-024-01414-4 article EN cc-by Antimicrobial Resistance and Infection Control 2024-06-05

Introduction Peripheral intravenous catheters (PIVCs) are the most commonly used vascular access device in hospitalised patients. Yet PIVCs may be complicated by local or systemic infections leading to increased healthcare costs. Chlorhexidine gluconate (CHG)-impregnated dressings help reduce PIVC-related infectious complications but have not yet been evaluated. We hypothesise an impregnated CHG transparent dressing, comparison standard polyurethane will safe, effective and cost-effective...

10.1136/bmjopen-2024-084313 article EN cc-by-nc-nd BMJ Open 2024-07-01

Abstract Introduction Early and accurate identification of high-risk patients with peripheral intravascular catheter (PIVC)-related phlebitis is vital to prevent medical device-related complications. Aim the study This aimed develop validate a machine learning-based model for predicting incidence PIVC-related in critically ill patients. Materials methods Four learning models were created using data from ≥ 18 years newly inserted PIVC during intensive care unit admission. Models developed...

10.2478/jccm-2024-0028 article EN cc-by ˜The œJournal of Critical Care Medicine 2024-07-01

10.1016/s1959-5182(23)61675-7 article FR EMC - Médecine d urgence 2024-06-01

Introduction. Patients with invasive medical devices are at high risk for infection. Skin colonization is the initial stage of these infections, leading to recommendation practices requiring disinfection using antiseptics. Microbial communities playing a major role in skin health could be impacted by antiseptic procedures. Aim. To characterize and compare bacterial samples from patients before an antisepsis procedure, after removal device itself, according nature molecule (povidone iodine or...

10.3390/antibiotics11091209 article EN cc-by Antibiotics 2022-09-07

<sec> <title>UNSTRUCTURED</title> Introduction: Peripheral intravenous catheters (PIVCs) are the most common vascular access device with hospitalised patients receiving at least one during hospital admission. Traditionally, a transparent dressing alone is considered adequate to safely secure PIVC, regardless of potential risk local and systemic infections. Although PIVCs have lowest incidence proven infection all devices (0.1%, 0.5 per 1000 catheter-days), nearly 2 billion purchased...

10.2196/preprints.52313 preprint EN 2023-08-30
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