A5100697757- Mathematical and Theoretical Epidemiology and Ecology Models
- COVID-19 epidemiological studies
- Evolution and Genetic Dynamics
- Acupuncture Treatment Research Studies
- Evolutionary Game Theory and Cooperation
- Healthcare and Venom Research
- Fractional Differential Equations Solutions
- Chinese history and philosophy
- Nonlinear Differential Equations Analysis
- Influenza Virus Research Studies
- Autophagy in Disease and Therapy
- Cellular transport and secretion
- Traditional Chinese Medicine Studies
- HIV Research and Treatment
- Ubiquitin and proteasome pathways
- Viral Infections and Vectors
- Receptor Mechanisms and Signaling
- Corneal surgery and disorders
- Nerve injury and regeneration
- Glaucoma and retinal disorders
- Mathematical Biology Tumor Growth
- Adolescent Sexual and Reproductive Health
- Immune Cell Function and Interaction
- Virology and Viral Diseases
- Ferroptosis and cancer prognosis
Shandong Normal University
2019-2025
National Clinical Research Center for Digestive Diseases
2022-2025
Air Force Medical University
2022-2025
Xijing Hospital
2022-2025
Jining Medical University
2019-2024
Henan Normal University
2019-2024
China University of Mining and Technology
2023-2024
Chongqing Medical University
2011-2024
Henan University of Economic and Law
2022
Shanxi University
2022
The long-term prophylactic effects of acupuncture for migraine are uncertain.To investigate the true compared with sham and being placed in a waiting-list control group prophylaxis.This was 24-week randomized clinical trial (4 weeks treatment followed by 20 follow-up). Participants were randomly assigned to acupuncture, or group. conducted from October 2012 September 2014 outpatient settings at 3 sites China. A total 249 participants 18 65 years old without aura based on criteria...
Ubiquitin-proteasome pathway (UPS) and autophagy-lysosome (ALP) are the two major protein degradation pathways, which critical for proteostasis. Growing evidence indicates that proteasome inhibition-induced ALP activation is an adaptive response. Transcription Factor EB (TFEB) a master regulator of ALP. However, characteristics TFEB its role in not fully investigated. Here we reported half-life around 13.5 h neuronal-like cells, degraded through both non-neuronal cells. Moreover, impairment...
Background M2-like tumor-associated macrophages (M2-like TAMs) have important roles in the progression and therapeutics of cancers. We aimed to detect novel TAM-related biomarkers hepatocellular carcinoma (HCC) via integrative analysis single-cell RNA-seq (scRNA-seq) bulk data construct a prognostic signature, reveal “immune landscape”, screen drugs HCC. Methods genes were obtained by overlapping marker TAM identified from scRNA-seq M2 macrophage modular weighted gene co-expression network...
A visible-light-induced deboronative alkylarylation of acrylamides with boronic acids was developed <italic>via</italic> a tandem reaction process.
Based on the model provided by Mulone and Straughan [1], we relax population which are constant obtain drug-free equilibrium is global asymptotically stable under some conditions. The system has only uniqueness positive endemic globally using second compound matrix.
An existing model is extended to assess the impact of some antimalaria control measures, by re‐formulating as an optimal problem. This paper investigates fundamental role three type controls, personal protection, treatment, and mosquito reduction strategies in controlling malaria. We work nonlinear framework. The existence uniqueness results solution are discussed. A characterization via adjoint variables established. optimality system solved numerically a competitive Gauss‐Seidel‐like...
Brain-derived neurotrophic factor (BDNF) signaling through its receptor, TrkB, modulates survival, differentiation, and synaptic activity of neurons. Both full-length TrkB (TrkB-FL) isoform T1 (TrkB.T1) receptors are expressed in neurons; however, whether they follow the same endocytic pathway after BDNF treatment is not known. In this study we report that TrkB-FL TrkB.T1 traverse divergent pathways binding to BDNF. We provide evidence neurons predominantly recycle back cell surface by a...
This paper deals with a simple mathematical model for the transmission dynamics of vector-borne disease that incorporates both direct and indirect transmission. The is analyzed using dynamical systems techniques it reveals backward bifurcation to occur some range parameters. In such cases, reproduction number does not describe necessary elimination effort rather described by value critical parame ter at turning point. extended assess impact control measures, re-formulating as an optimal...
In this paper, a two-strain model that links immunological and epidemiological dynamics across scales is formulated. On the within-host scale, two strains eliminate each other with strain larger reproduction persisting. However, on population scale superinfection possible, number super-infecting smaller number. The models are linked through age-since-infection structure of variables. addition, between-host transmission disease-induced death rate depend viral load. numbers, numbers invasion...
In this paper, an age-structured epidemicmodel is formulated to describe the transmission dynamics ofcholera. The PDE model incorporates direct and indirect transmissionpathways, infection-age-dependent infectivity variable periodsof infectiousness. Under some suitable assumptions, modelcan be reduced multi-stage models investigated in theliterature. By using method of Lyapunov function, we establishedthe dynamical properties model, results show thatthe global completely determined by...
Catalytic reduction has been regarded as one of the most efficient strategy for organic pollutants removal from aqueous solution. However, lack catalyst prevents its practical application. Herein, we design a simple and environmental friendly fabrication 3D Ag nanoparticles/Ti3C2Tx/polyacrylamide (Ag/MX/PAM) composite hydrogel high catalyst. In this hydrogel, nanoparticles, Ti3C2Tx (MXene) polyacrylamide (PAM) act active species, electron transfer medium high-capacity adsorbent respectively....
The aim of this study was to analyze the clinical significance and prognostic value CD8
Background: Stomach adenocarcinoma (STAD) is the fifth most common tumor worldwide, imposing a significant disease burden on populations, particularly in Asia. Oxidative stress well-known to play an essential role occurrence and progression of malignancies. Our study aimed construct prediction model by exploring correlation between oxidative stress-related genes prognosis patients with STAD. Method: STAD data from TCGA were used identify differentially expressed (OSGs), GEO serving as...