- Body Composition Measurement Techniques
- Radiomics and Machine Learning in Medical Imaging
- Nutrition and Health in Aging
- Medical Imaging Techniques and Applications
- Bone health and osteoporosis research
- Lung Cancer Treatments and Mutations
- Nutritional Studies and Diet
- Thyroid Cancer Diagnosis and Treatment
- Thermoregulation and physiological responses
- Thyroid and Parathyroid Surgery
- MRI in cancer diagnosis
- Brain Metastases and Treatment
- Advanced MRI Techniques and Applications
- Atherosclerosis and Cardiovascular Diseases
- Parathyroid Disorders and Treatments
- Antimicrobial Resistance in Staphylococcus
- Functional Brain Connectivity Studies
- Epilepsy research and treatment
- Hip and Femur Fractures
- Systemic Lupus Erythematosus Research
- Lipid metabolism and disorders
- Bone Metabolism and Diseases
- Orthopedic Infections and Treatments
- Head and Neck Anomalies
- Bone and Joint Diseases
First Affiliated Hospital of Jinan University
2015-2025
Peking University
2023
Jinan University
2014
The aims of the study were to develop sex- and age-specific percentiles for lean mass index (LMI), appendicular LMI (aLMI), fat (FMI), body distribution indices in Chinese adults using dual-energy X-ray absorptiometry (DXA), compare those with other ethnicities US NHANES data.Whole-body regional (FM) measured DXA 5688 healthy males (n = 1693) females 3995) aged 20-90 years. Body expressed as % trunk/% legs, trunk/appendicular FM ratio (FMR), android/gynoid FMR. Percentile curves LMI, aLMI,...
Background Osteoporosis in pre-dialysis chronic kidney disease (CKD) patients has been overlooked, and the risk factors of osteoporosis these have not adequately studied.
The vascular endothelial growth factor A (VEGF-A)/VEGF receptor 2 (VEGFR-2) signaling pathway is pivotal in regulating angiogenesis. We have synthesized a linear peptide-based VEGFR-2-targeted positron emission tomography (PET) tracer, but its target affinity and vivo stability need further improvement. In this study, we developed two novel 64Cu-labeled PET dimer tracer [64Cu]VEGF2215 [64Cu]VEGF2216 modified with pegylated branched linker, respectively, to optimize pharmacokinetic properties...
Background: This study aimed to establish gender-related differences and the percentile curves for total body fat mass percentage (Total FM%), trunk/appendicular ratio (TrAppFMR), as % trunk/% lower limb (TrLLFMR) in Chinese children adolescents using dual-energy X-ray absorptiometry (DXA). Methods: Children (n = 1541; 764 girls) aged 5 19 years were recruited from southern China. Total FM% regional FM measured by DXA. TrAppFMR values calculated trunk divided appendicular FM, TrLLFMR between...
Visceral adipose tissue (VAT) is becoming a recognized cardiovascular (CV) risk factor. This study aimed to evaluate body composition, especially VAT, in systemic lupus erythematosus (SLE) and explore the association between VAT SLE disease-related factors.Ninety-eight inpatients with 108 age- mass index (BMI)-matched healthy controls were included. Demographic clinical parameters recorded. The was measured by dual-energy x-ray absorptiometry.The mean age disease duration of patients 46.4 ±...
Abstract Background Being overweight or obese has become a serious public health concern, and accurate assessment of body composition is particularly important. More precise indicators fat include visceral adipose tissue (VAT) mass total percentage (TBF%). Study objectives included examining the relationships between abdominal mass, measured by quantitative computed tomography (QCT), whole-body regional masses, dual energy X-ray absorptiometry (DXA), as well to derive equations for...
Objective To optimize the automated radiosynthesis of purinergic ion channel receptor 7 (P2X7R) imaging agent 18 F-JNJ64413739 and evaluate its potential for brain in osteoporotic model rats. Methods A more electron-deficient nitropyridine was employed as labeling precursor to facilitate F-labeling. The conducted on an AllinOne synthesis module, followed by purification via high-performance liquid chromatography (HPLC). resulting subjected quality control tests. Small-animal PET/CT studies...
Objectives This study was an attempt to investigate the variation trend of body composition with ageing and explore association between regional bone mineral density (BMD). Design Cross-sectional study. Setting participants A total 5749 healthy adults aged 20–95 years recruited from 2004 2017. Primary outcome measures Whole-body lean mass (LM), fat (FM), android FM, gynoid appendicular (ALM) BMD in lumbar spine, femoral neck hip were obtained by dual-energy X-ray absorptiometry (DXA). The...
This study aimed to establish and validate the nomograms for predicting overall survival (OS) probabilities in differentiated thyroid cancer (DTC) patients who received did not receive radioiodine therapy (RAI), respectively.In this study, 11, 099 diagnosed with DTC Surveillance, Epidemiology, End Results (SEER) database from 2004 2016 were selected. Whether they have RAI, are divided into RAI (n=6427) non-RAI (n=4672) groups. They randomly assigned either a training cohort (RAI: n=4498,...
Aim . To develop predictive equations of lean body mass (LBM) suitable for healthy southern Chinese adults with a large sample. LBM measured by dual-energy X-ray absorptiometry (DXA) are considered as the standard ones. Methods Retrospective analysis was conducted on consecutive people who did total measurement DXA from July 2005 to October 2015. People diseases that might affect were excluded and overall 12,194 subjects included in this study. Information about 10,683 (2,987 males 7,696...
Brain metastases (BMs) are a major cause leading to the failure of treatment management for non-small-cell lung cancer (NSCLC) patients. The purpose this study was evaluate predictive value baseline metabolic tumor burden on 18F-FDG PET/CT measured with volume (MTV) and total lesion glycolysis (TLG) brain development in patients locally advanced after treatment. Forty-seven stage IIB-IIIC NSCLC who underwent examinations were retrospectively reviewed. maximum standardized uptake (SUVmax),...
Real-time visual perception is essential for animals to survive in a complicated natural environment and robots interact with moving targets. However, delays generally occur during the signal transfer processing both robots, these would produce errors real-time interactions physical world. Natural facts have shown that can perfectly compensate pervasive delays. In this paper, we propose novel effective position model (PPM) based on spiking neural networks (SNNs) address ambivalent situation...
Abstract Background Standardized uptake value (SUV) normalized by lean body mass ([LBM] SUL) is recommended as metric PERCIST 1.0. The James predictive equation (PE) a frequently used formula for LBM estimation, but may cause substantial error an individual. purpose of this study was to introduce novel and reliable method estimating limited-coverage (LC) CT images from PET/CT examinations test its validity, then analyse whether SUV normalised LC-based could change the 1.0 response...
Dual-energy X-ray absorptiometry (DXA) is a well-accepted tool for monitoring skeletal and body composition changes in biomedical studies. The nonhuman primate model suitable studies exploring the pathogenesis of novel treatments osteoporosis. Our objectives are to determine precision DXA detection cynomolgus monkeys identify difference lumbar bone mineral density (BMD) with various segment selections.Thirty adult female underwent duplicate total scans. Total (BMDTB) composition, including...
The precision reflecting repeated measurement error of quantitative parameters flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for evaluating the therapeutic effect solid tumor can help observe whether a real biologic change in glucose metabolism occurred, or if was caused by errors before and after treatment.A total 18 VX2 tumor-bearing male New Zealand rabbits confirmed pathology were used, three which used determining best scanning time...
Brain metastases (BMs) are common complications in patients with non-small cell lung cancer (NSCLC). The purpose of this study was to investigate whether the metabolic parameters derived from preoperative 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) can predict BM development surgically resected NSCLC.We retrospectively reviewed 128 consecutive stage I-IIIA NSCLC who underwent 18F-FDG PET/CT before curative surgery at First Affiliated Hospital...
Abstract Objective To explore the feasibility of postoperative diagnostic 131 I whole-body planar scans (Dx-WBS) in papillary thyroid cancer (PTC) patients, and to clarify its value for accurate staging, risk stratification, radioactive iodine (RAI) treatment management. Design Retrospective study from 2015 2021. Setting A total 1294 PTC patients tertiary referral hospital. Participants Patients with differentiated who underwent total/subtotal thyroidectomy were included. non-PTC...