A5011334815- Cancer-related gene regulation
- Cell Adhesion Molecules Research
- Helicobacter pylori-related gastroenterology studies
- Acute Kidney Injury Research
- Renal and related cancers
- Extracellular vesicles in disease
- Bone and Joint Diseases
- Birth, Development, and Health
- RNA Research and Splicing
- Bone health and osteoporosis research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Skin Protection and Aging
- Poisoning and overdose treatments
- Artificial Intelligence in Healthcare
- Parathyroid Disorders and Treatments
- Artificial Intelligence in Healthcare and Education
- Hair Growth and Disorders
- Cancer-related molecular mechanisms research
- Renal and Vascular Pathologies
- Dermatologic Treatments and Research
First Affiliated Hospital of Jinan University
2021-2025
Fudan University Shanghai Cancer Center
2022
Abstract Background SLCO4A1-AS1 was found to be upregulated in several cancer types, including colorectal (CRC). However, the detailed roles of CRC remain elucidated. Therefore, we investigated functions, mechanism, and clinical significance tumourigenesis. Methods We measured expression tissues using qRT-PCR determined its correlation with patient prognosis. Promoter methylation analyses were used assess status SLCO4A1-AS1. Gain- loss-of-function assays evaluate effects on growth vitro...
Acute kidney injury (AKI) is a susceptible factor for chronic disease (CKD). There still lack of effective prevention methods in clinical practice. This study investigated the protective effect urinary exosomes from premature infants on cisplatin-induced acute injury. Here we isolated fresh urine infants. A C57BL/6 mice model was given 100 ug 24 hours after establishment. The kidneys were collected pathological examination and evaluation renal tubular damage apoptosis. In vitro experiment,...
Background Osteoporosis in pre-dialysis chronic kidney disease (CKD) patients has been overlooked, and the risk factors of osteoporosis these have not adequately studied.
Background: Although lactated Ringer's (LR) solution is widely used in managing patients with acute kidney injury (AKI), its specific impact on mortality remains unclear. This retrospective cohort study aimed to evaluate the effects of LR administration survival outcomes severely ill AKI. Methods: Critically AKI were identified using data from Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. Propensity score matching (PSM) was employed address baseline discrepancies...
<title>Abstract</title> <bold>Objective</bold>: The global prevalence of chronic kidney disease (CKD) is escalating, particularly for end-stage renal (ESRD), which has led to greater dependence on hemodialysis. This upswing exerts substantial strains patient families and healthcare systems. A critical concern during hemodialysis the emergence Intradialytic Hypertension (IDH), carries significant health risks. Delayed management IDH can lead severe cardiovascular cerebrovascular...
Aim: Acute kidney injury (AKI), a global public health issue, not only causes millions of deaths every year, but is also susceptible factor for chronic disease (CKD). Nephrotoxic drugs are an important cause AKI. There still lack effective and satisfactory prevention method in clinical practice. This study investigated the protective effect exosomes derived from urine premature infants on cisplatin-induced acute injury. Methods: Isolation fresh infants: The characteristics were determined by...