A5015231090- Advanced Fiber Optic Sensors
- Advanced Biosensing Techniques and Applications
- Photonic and Optical Devices
- Plasmonic and Surface Plasmon Research
- Biosensors and Analytical Detection
- Analytical Chemistry and Sensors
- Advanced Chemical Sensor Technologies
- Advanced biosensing and bioanalysis techniques
- Nanofabrication and Lithography Techniques
- Pesticide and Herbicide Environmental Studies
- Analytical chemistry methods development
- Pharmaceutical and Antibiotic Environmental Impacts
- Monoclonal and Polyclonal Antibodies Research
- Potato Plant Research
- Microfluidic and Bio-sensing Technologies
- Photonic Crystal and Fiber Optics
- Nanomaterials and Printing Technologies
- Nanowire Synthesis and Applications
- Semiconductor Lasers and Optical Devices
- Microfluidic and Capillary Electrophoresis Applications
- COVID-19 diagnosis using AI
- Electrowetting and Microfluidic Technologies
University of Campania "Luigi Vanvitelli"
2022-2025
Molecularly imprinted polymers (MIPs) can be combined with optical fibers (OFs) to create various sensor configurations, yielding low-cost and highly sensitive extrinsic intrinsic sensors. In this work, an MIP-based fiber is obtained by two silica OFs connected via waveguide using MIP as a core of micrometer size (micro OF-MIP-OF sensor). The proposed sensing approach used only receptors implements intensity-based configuration. MIPs present several advantages over bio-receptors exploited...
In this work, a 3D-printed plasmonic chip based on silver-gold bilayer was developed in order to enhance the optical response of surface plasmon resonance (SPR) probe. More specifically, numerical and experimental results were obtained SPR platform bilayer. Then, optimized probe's gold interface functionalized with specific antibody directed against p27 Kip1 protein (p27), an important cell cycle regulator. The biosensor tested for detection good selectivity limit 55 pM. system demonstrated...
The characteristics of Plastic Optical Fibers (POFs) are exploited to realize simple, highly sensitive, and low-cost bio/chemical sensors via innovative schemes. POF's multimode characteristic the simple modification processes used obtain novel ultra-sensitive platforms that can be combined with different kinds receptors (bio-mimetic or biological receptors) detect specific substances in ranges for several application fields. This review reports POF based on optical transduction principles...
An optical–chemical sensor based on two modified plastic optical fibers (POFs) and a molecularly imprinted polymer (MIP) is realized tested for the detection of 2-furaldehyde (2-FAL). The 2-FAL measurement scientific topic great interest in different application fields, such as human health life status monitoring power transformers. proposed by using POFs segmented waveguides (SW) coupled through micro-trench milled between then filled with specific MIP detection. experimental results show...
A plastic optical fiber (POF)-based device for biosensing strategies has been developed to monitor several protein–protein interactions at ultra-low concentrations without functionalization processes, exploiting plasmonic phenomena. In this work, novel tests were applied different kinds of analyte–receptor interactions, such as interleukins, where the bioreceptor’s (protein antibody) molecular weight is roughly ten times that analyte interleukin), while intracellular bioreceptors and small...
Interleukins are involved in several diseases and cancers, their detection monitoring of great interest. Their low abundance short half-lives suggest the need to develop rapid, specific, highly sensitive platforms, easily integrable point-of-care (POC) systems. Among other interleukins, interleukin IL-17A is associated with inflammations, neurodegenerative diseases, no biosensors have been previously reported for its detection. In this work, IL-17A, a nanoplasmonic sensor based on natural...
Optical–chemical sensors based on optical fibers can be made in reflection or transmission schemes. In the scheme, sensing area is typically present at end of fiber, and light source detector are placed same side fiber. This approach exploited to achieve chemical probes useful several application fields where remote required. this work, obtain an extrinsic fiber sensor a two used monitor chemically sensitive region achieved by C-shaped waveguide with molecularly imprinted polymer (MIP) as...
Polymer-based surface plasmon resonance (SPR) sensors can be used to realize simple, small-size, disposable, and low-cost biosensors for application in several fields, e.g., healthcare. The performance of SPR based on optical waveguides changed by tuning parameters, such as the dimensions shape waveguides, refractive index core, metal nanofilms excite phenomenon. In this work, order develop, experimentally test, compare polymer-based plasmonic sensors, realized using with different core...
An innovative optical-chemical sensor has been used to detect the 2-furaldehyde (2-FAL) in milk. The proposed sensing approach exploits refractive index changing a microstructured chip based on plastic optical fiber (POF) with orthogonal micro-holes containing specific molecularly imprinted polymer (MIP). This POF-MIP chemical modifies surface plasmon resonance (SPR) phenomena excited another realized POFs (SPR-POF) and connected series. configuration MIP receptors avoiding any modification...
A versatile and low-cost plasmonic biosensor was designed, realized, tested by combining a bioreceptor layer with probe based on two plastic optical fibers (POFs) built-in sensing chip carried out via multilayer UV-curable adhesives. The proposed sensitive has been developed to excite the surface plasmon resonance (SPR) phenomenon gold in contact monitored layer. More specifically, binding interaction between its analyte studied for first time exploiting SPR platforms First, resin block...
Optical biosensors based on plasmonic phenomena are used in several fields, such as medical applications. This work presents simple sensor development phases to realize a small-size, highly sensitive, V-shaped, and low-cost surface plasmon resonance (SPR) platform. First, resin block was achieved by 3D printer with V-shaped slot its surface. To carry out mirror the slides of this slot, silver layer sputtered before UV-cured optical adhesive filled achieve core multimode waveguide. Then,...
In this work, two sensor configurations have been realized and tested to measure micro/nano-liquid volumes. Measurement of micro/nano volumes is high interest for a variety application domains, such as calibrate micropipettes biochemical uses, or examine volume variations prevent liquid leakage. The proposed chips are based on patches polymeric light diffusing fibers (P-LDFs), opportunely modified in different ways. More specifically, one configuration polishing process, whereas the other...
Optical fiber biosensors can be used to develop point-of-care tests (POCTs) for detecting viruses and bacteria in several matrices. In particular, the surface plasmon resonance (SPR) localized SPR phenomena (LSPR) excited by exploiting low-cost small-size optical chips. Generally, or LSPR sensors are realized using kinds of modified fibers (silica, plastic, specialty) other waveguides (e.g., slab, spoon-shaped waveguides, etc.). More specifically, classified as intrinsic extrinsic. "optical...
In this work, a novel sensing approach used to develop micro-liquid volume measurement system is exploited. This methodology exploits the effects induced by small liquid in contact with patch of plastic light-diffusing fiber (LDF) connected at input surface plasmon resonance (SPR) sensor realized D-shaped optical (POF). More detail, fixed solution present on SPR-POF sensor, when different LDF patch, mode profile light into and, so, changes, producing shift SPR spectra. As proof concept,...
In this work, the classification and identification of two different types solvent solutions (i.e., isopropanol:water ethanol:water) were achieved by exploiting solution properties combined with Artificial Intelligence. More in detail, a Surface Plasmon Resonance (SPR) sensor based on D-shaped plastic optical fibers (POFs) acted as an transducer to build proper dataset. The plasmonic probe was used monitor bulk refractive index variations due evaporation phenomenon over time. collected...