A5003158689- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Surgical Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Biomedical and Engineering Education
- Gastroesophageal reflux and treatments
- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
- Colorectal and Anal Carcinomas
- Multiple and Secondary Primary Cancers
- Sarcoma Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Neurofibromatosis and Schwannoma Cases
- Enhanced Recovery After Surgery
- Ureteral procedures and complications
- Biomedical Ethics and Regulation
- Helicobacter pylori-related gastroenterology studies
- Surgical Simulation and Training
- Lung Cancer Diagnosis and Treatment
- Quality and Safety in Healthcare
- Hemostasis and retained surgical items
- Thyroid and Parathyroid Surgery
Osaka International Cancer Institute
2016-2025
Osaka University
2018-2025
Sakai Municipal Hospital
2021-2024
Ebara (Japan)
2024
Yao Tokushukai General Hospital
2012
Abstract The GLOW and SPOTLIGHT trials have demonstrated the efficacy of chemotherapy plus zolbetuximab for HER2-negative, claudin-18 isoform 2 (CLDN18.2)–positive unresectable advanced or recurrent gastric cancer (AGC)/gastroesophageal junction cancer. However, data on adverse events in real-world clinical practice are still insufficient. Specifically, gastritis protein-losing enteropathy (PLE), which were not evident either trials, generally recognized. This paper reports notable course...
Abstract Background The increasing incidence of gastric cancer in the elderly underscores need for an in-depth understanding challenges and risks associated with surgical interventions this demographic. This study aims to investigate risk factors prognostic indicators non-cancer-related mortality following curative surgery patients. Methods retrospective analysis examined 684 patients pathological Stage I—III who underwent resection between January 2012 December 2021. focused on aged 70...
Abstract Background As the prevalence of gastric cancer rises in aging populations, managing surgical risks and comorbidities elderly patients presents a unique challenge. The Comprehensive Preoperative Assessment Support (CPAS) program, through comprehensive preoperative assessments, aims to mitigate stress improve outcomes by enhancing patient awareness preparation. This study investigates efficacy CPAS incorporating frailty sarcopenia evaluations, short-term patients. Methods A...
<title>Abstract</title> <bold>Background:</bold> Stage IV gastric cancer remains challenging to treat despite recent advances in systemic therapy. Among patients with favorable responses chemotherapy, conversion surgery aiming for R0 resection has shown promise improving survival. Immune checkpoint inhibitors (ICIs) have become a key component of treatment, but their prognostic impact the setting unclear. <bold>Methods:</bold> This retrospective single-center study included 98 who underwent...
Summary Background Immunotherapy combined with chemotherapy has been the first-line treatment for metastatic or unresectable locally advanced esophageal cancer. However, postoperative recurrences have not sufficiently investigated. We investigated clinical outcomes of pembrolizumab plus cisplatin 5-fluorouracil (CF) therapy recurrent squamous cell carcinoma. Methods retrospectively analyzed 100 consecutive patients recurrence and compared their response survival in to CF conventional...
Abstract Background and aims There is no current consensus regarding the best practices for techniques devices in laparoscopic hepatic parenchymal transection. To compare safety, efficacy, outcomes between coagulation non-coagulation while using clamp-crush technique modern transections. Methods The clinical of patients who underwent liver resection hepatocellular carcinoma metastasis by with a Biclamp (n = 74) Harmonic ACE 92), technique, were evaluated. Additionally, we checked fluid...
Abstract In flexible gastrointestinal (GI) endoscopy, endoscopic insufflation is crucial and directly affects visualization. Optimal visualization enables endoscopists to conduct better examinations administer optimal treatments. However, typically performed manually subjective. We aimed measure the GI endoluminal pressure during endoscopy. Participants underwent esophagogastroduodenoscopy (EGD) at our endoscopy center. Pressure measurement was conducted after completing diagnostic or...
Abstract Background Minimally invasive total gastrectomy (MITG) is a mainstay for curative treatment of patients with gastric cancer. To define and standardize optimal surgical techniques further improve clinical outcomes through the enhanced MITG quality, there must be consensus on key technical steps lymphadenectomy anastomosis creation, which currently lacking. This study aimed to determine an expert from international panel regarding aspects performance oncological indications using...
Achalasia patients occasionally coexist with esophageal hiatal hernias. The purpose of this study was to clarify the incidence and clinical features achalasia cases concomitant hernia, investigate whether our surgical technique appropriate.Consecutive who underwent laparoscopic Heller myotomy Dor fundoplication (LHD) were extracted from prospectively compiled database, perioperative outcomes presence rate hernia obtained.We enrolled 58 LHD 2005 2016. Hiatal seen in 12 (20.7%) without...
Abstract Background Real-world clinical outcomes of and prognostic factors for nivolumab treatment esophageal squamous-cell carcinoma (ESCC) remain unclear. This study aimed to evaluate real-world monotherapy in association with relevant parameters recurrent/unresectable advanced ESCC patients. Methods population-based multicenter cohort included a total 282 patients from 15 institutions who received as second-line or later therapy between 2014 2022. Data, including the best overall...
Although intramural metastasis (IM) in esophageal cancer is considered a poor prognostic factor, there are only limited reports detailing its clinicopathologic characteristics and impact.We retrospectively included patients with squamous cell carcinoma (ESCC) esophagectomy at our institution between 2010 2016. We compared metastases (IMs) (IM group) versus those without IMs (non-IM to clarify the clinical significance of ESCC.A total 23 (3.9%) out all 597 were identified have IM. The located...