A5019168174- Childhood Cancer Survivors' Quality of Life
- Reproductive Biology and Fertility
- Neutropenia and Cancer Infections
- Simulation-Based Education in Healthcare
- Anesthesia and Pain Management
- Reproductive Health and Technologies
- Nausea and vomiting management
- Oral health in cancer treatment
- Antibiotics Pharmacokinetics and Efficacy
- Ovarian function and disorders
- Heart Rate Variability and Autonomic Control
- Pediatric Pain Management Techniques
- Nursing Roles and Practices
- Sperm and Testicular Function
- Patient Safety and Medication Errors
- Acute Lymphoblastic Leukemia research
- Family and Patient Care in Intensive Care Units
- Palliative Care and End-of-Life Issues
- Head and Neck Cancer Studies
- Cardiac Health and Mental Health
- Hemodynamic Monitoring and Therapy
- Testicular diseases and treatments
- Cardiovascular Health and Disease Prevention
- Fungal Infections and Studies
- Methemoglobinemia and Tumor Lysis Syndrome
University of Toronto
2004-2020
Hospital for Sick Children
2007-2020
SickKids Foundation
2004-2020
Thames Valley Hospital
2020
Health Education North West
2020
Health Education England
2020
Newbury College
2020
Organic Research Centre
2018
Versar (United States)
2015
Children's Hospital of Eastern Ontario
2015
Background: Pain is one of the most common and distressing symptoms reported by adolescents with cancer. Despite advancements in pain assessment management research, due to cancer and/or its treatments continues be poorly managed. Our research group has developed a native iPhone application (app) called Squad tackle problem managed adolescent group. The app functions as an electronic diary unique ability collect data on intensity, duration, location, impact adolescent's life (ie,...
We evaluated the construct validity (including responsiveness), reliability, and feasibility of Pain Squad multidimensional smartphone-based pain assessment application (app) in children adolescents with cancer, using 2 descriptive studies repeated measures. Participants (8-18 years) undergoing cancer treatment were drawn from 4 pediatric centers. In study 1, 92 participants self-reported their level twice daily for weeks app to assess reliability. 2, 14 recorded a day 1 week before after...
Background: Coronary heart disease is a major cause of disability.There has been little study the effect cardiac rehabilitation on measures self-reported physical functioning.Methods: Physical functioning was measured using Medical Outcomes Study-Short-Form Questionnaire.Determinants function were analyzed in 303 patients with coronary disease.Response to 3-month exercise program then determined.Results: At baseline, women had lower scores than men, despite similar age and diagnostic...
Our primary objective was to describe and compare parents' healthcare professionals' strength of preference scores for outpatient oral antibiotic relative inpatient parenteral treatment low-risk febrile neutropenic children. secondary identify predictors treatment.Respondents were parents children receiving cancer chemotherapy, pediatric oncology professionals. First, the options described, respondent indicated their initially preferred option. The next ranked how important seven factors...
Fertility preservation options are limited in prepubertal boys with cancer. Worldwide there has been growing interest testicular tissue cryopreservation as a promising experimental strategy to address future infertility. We measured and compared parent, male cancer survivor provider willingness accept the risk of biopsy among cancer, identified reactions disclosure practices.We conducted multicenter study that included 153 parents 77 survivors childhood 30 oncology providers. The threshold...
Tumor lysis syndrome (TLS) is a well-recognized complication of acute lymphoblastic leukemia (ALL). The ability to predict children at differing risk TLS would be an early step toward risk-based approaches. objectives the current study were 1) describe prevalence and predictors in childhood ALL 2) develop sensitive prediction rule identify patients lower TLS.Health records aged </=18 years who diagnosed with between 1998 2004 reviewed. was defined by presence >/=2 laboratory abnormalities...
This retrospective review evaluates the response to caspofungin when given children with febrile neutropenia and describes adverse effects attributable caspofungin, including risk of hepatotoxicity during concomitant therapy cyclosporine. Sixty-seven courses administered 56 patients (1–17 years) were surveyed; 53 (79%) resulted in an overall favorable response. Ten (15% courses) experienced drug-related event that was probably or possibly caspofungin. Rash hypokalemia most commonly...
At our institution, patients who receive once-daily dosing of gentamicin have serum concentrations determined 3 and 6 hours after dose administration. Patients with single-lumen central venous catheters the 3-hour samples drawn peripherally. The objective this study was to evaluate extent agreement between peripheral catheter administration.In prospective, observational study, provided both a blood sample for determination concentration. order sampling (central versus first) randomized....
It is widely reported that emergency presentations in general practice are increasing1,2 and recent audit data from practices we have worked with Thames Valley support these observations: 74/76 (97%) GPs seeing at least one presentation the previous year 61/67 (91%) experienced delays ambulance attendance. Managing conditions such as a myocardial infarction, life-threatening asthma, or acute sepsis places burden on primary care teams to initiate management for potentially seriously unwell...
PURPOSE: Fertility is an important issue for adolescents and young adults with cancer facing potential infertility. Egg cryopreservation options exist, but information sometimes overwhelming. We evaluated a fertility preservation educational video assessed patient family knowledge impressions at pre- post-video timepoints. METHODS: developed whiteboard to explain egg patients families. The was on the basis of education best practices (readability, understandability, actionability)....
The role of the nurse practitioner has been long established in outpatient setting pediatric oncology. inpatient described to a lesser extent. This review clinical specialist/nurse on 27-bed oncology unit at Hospital for Sick Children Toronto, Ontario, Canada, will describe and strategies its implementation. facilitates provision quality care children families admitted unit.
GP teams manage a wide spectrum of acutely unwell and deteriorating patients, these are unexpected, high risk, low frequency events. Ambulance delays mean patients may need prolonged input prior to transfer. There is little best practice guidance for many emergencies seen in primary care. Evidence from secondary care shows improved non-technical skills when checklists used emergency simulations. We have previously presented early phases the MAGIC project design Quick Reference Handbook (QRH)...