- Microbial infections and disease research
- Aquaculture disease management and microbiota
- Animal Virus Infections Studies
- Veterinary medicine and infectious diseases
- Pneumonia and Respiratory Infections
- Leptospirosis research and findings
- Herpesvirus Infections and Treatments
- Bacteriophages and microbial interactions
- Mycobacterium research and diagnosis
- Animal Nutrition and Physiology
- Vector-borne infectious diseases
- Plant Virus Research Studies
- Pleural and Pulmonary Diseases
- Animal Disease Management and Epidemiology
- Salmonella and Campylobacter epidemiology
- Viral Infections and Vectors
- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
Universidade Estadual Paulista (Unesp)
2020-2024
Porcine Respiratory Diseases Complex (PRDC) is a multifactorial disease that involves several bacterial pathogens, including Mycoplasma hyopneumoniae (M. hyopneumoniae), Actinobacillus pleuropneumoniae (A. pleuropneumoniae), Pasteurella multocida (P. multocida), Glaesserella parasuis (G. parasuis), and Streptococcus suis (S. suis). In pigs, the infection may cause lesions such pleurisy, which can lead to carcass condemnation. Hence, 1015 carcasses were selected from three different...
Abstract Mycoplasma ( M .) hyopneumoniae is the main pathogen of porcine enzootic pneumonia (PEP). Its controlling challenging, and requires alternative strategies. This study aimed to develop an oral vaccine against M. using a nanostructured mesoporous silica (SBA-15) as adjuvant, compare its effect with intramuscular (IM) commercial (CV). Fifty 24 day-old . -free piglets composed five equal groups for different immunization protocols, consisting CV and/or (OI). Control did not receive any...
Mycoplasma hyopneumoniae ( M. ) is considered the primary causative agent of porcine enzootic pneumonia (EP), a chronic contagious respiratory disease that causes economic losses. Obtaining new pathogenic isolates and studying genome virulence factors are necessary. This study performed complete sequencing analysis two Brazilian strains, UFV01 UFV02, aiming to characterize in terms sequence type. The revealed main genes mhp385 , mhp271 MHP_RS03455 p102 p97 p216 MHP_RS00555 mhp107 ST-123,...
So far, three porcine hemoplasmas (PH) have been identified, namely Mycoplasma suis, parvum, and haemosuis. The first one is the main agent associated with hemoplasmosis, a possible cause of economic losses in pig production. Thus, this work aimed to detect quantify PH 16S rRNA finishing pigs associate its load estimate average daily weight gain (ADWG). For purpose, whole blood samples from 318 were collected at an age 75 days (d0) when entered phase 105 later (d105). To calculate ADWG,...
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Respiratory diseases, such as pleurisy and pneumonia, cause significant health economic losses in pig production. This study evaluated 867 finishing pigs from a farm with history of respiratory issues, using macroscopic lesion scoring (SPES CVPC), histopathological analysis, qPCR diagnostics, modeling. Severe (scores 3 4) was observed 42.1% carcasses strongly correlated higher bacterial loads Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, Pasteurella multocida. lesions reduced...
Mycoplasma hyopneumoniae is a difficult-to-control bacterium since commercial vaccines do not prevent colonization and excretion. The present study aimed to evaluate the performance of an orally administered vaccine composed antigens extracted from incorporated into mesoporous silica (SBA-15), which has adjuvant-carrier function, aiming potentiate action intramuscular vaccine. A total 60 piglets were divided four groups (n = 15) submitted different vaccination protocols as follows, Group 1:...
Leptospirosis is a zoonotic disease that poses significant threat to human and animal health worldwide. Among different species, pigs are known play crucial role in the transmission of pathogenic Leptospira spp. This study aimed investigate prevalence infection associated risk factors backyard state Paraná, Brazil. A set 1393 blood samples were collected from on 188 subsistence properties 136 municipalities Paraná tested using microscopic agglutination test (MAT) detect antibodies against 24...
The use of antimicrobials as growth promoters and disease prevention is being constantly reduced in several animal production systems, including the swine industry. Therefore, this study aimed to evaluate effectiveness using acidifiers control Salmonella Typhimurium 65-day-old pigs by detecting pathogen organs at euthanasia. For this, 24 piglets were divided into two experimental groups consisting 12 each. An untreated group (G1) a treatment (G2) received liquid organic acidifier drinking...
Leptospirosis is a zoonotic disease that poses significant threat to human and animal health worldwide. Among different species, pigs are known play crucial role in the transmission of pathogenic Leptospira spp. This study aimed investigate prevalence infection associated risk factors subsistence pig production state Paraná, Brazil. A total 1393 serum samples were collected from on 188 properties regions state, tested using microscopic agglutination test (MAT) detect antibodies against 24...
Mycoplasma hyopneumoniae is the causative bacterium of porcine enzootic pneumonia and one primary etiologic agents respiratory disease complex. Most Brazilian commercial pig farms are positive for this pathogen. However, prevalence pathogen in backyard has not been described, to our knowledge. Therefore, we aimed determine M. state Paraná, Brazil. In January–March 2020, collected 585 serum samples from pigs 187 non-vaccinated herds. We tested sera with an indirect ELISA anti– antibodies...
Mycoplasma hyopneumoniae is the primary agent of Swine Enzootic Pneumonia (SEP). Vaccines reduce clinical manifestation disease but do not prevent infection. The present study aimed to evaluate use antimicrobial drugs minimize impact M. hyopneumoniae. For this, 32 pregnant female pigs and their litters were selected then followed from birth slaughter. involved three experimental groups that received metaphylactic treatment with different protocols involving tilmicosin, valnemulin,...
Mycoplasma (M.) hyopneumoniae, the etiological agent of swine enzootic pneumonia, has been reported to increase susceptibility secondary infections and modulate respiratory microbiota in infected pigs. However, no studies have assessed influence M. hyopneumoniae on diversity under experimental conditions. Therefore, this study evaluated impact infection experimentally over time. To accomplish this, 12 weaned pigs from a hyopneumoniae-free farm were divided into two groups: strain 232 (n = 8)...