A5101837675- Wound Healing and Treatments
- Surgical Sutures and Adhesives
- Traditional Chinese Medicine Analysis
- Medicinal Plant Pharmacodynamics Research
- Periodontal Regeneration and Treatments
- Influenza Virus Research Studies
- Respiratory viral infections research
- Reconstructive Surgery and Microvascular Techniques
- Liver Disease Diagnosis and Treatment
- Infant Nutrition and Health
- Laser Applications in Dentistry and Medicine
- Acupuncture Treatment Research Studies
- Cancer-related molecular mechanisms research
- Bioactive Natural Diterpenoids Research
- Breast Lesions and Carcinomas
- RNA and protein synthesis mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Mesenchymal stem cell research
- Traditional Chinese Medicine Studies
- Chemotherapy-related skin toxicity
- Diet, Metabolism, and Disease
- Neonatal Respiratory Health Research
- Diabetic Foot Ulcer Assessment and Management
- Hemostasis and retained surgical items
- Andrographolide Research and Applications
Ministry of Health and Welfare
2014-2024
National Chung Hsing University
2013-2024
Taichung Hospital
2013-2024
Memorial Hospital of South Bend
2011
Chang Gung Memorial Hospital
2011
Tanshinone I (T1) and tanshinone II (T2) are the major diterpenes isolated from Danshen (Salvia miltiorrhiza Bunge). Three human lung adenocarcinoma cell lines, A549, CL1-0, CL1-5, were treated with T1 T2 for in vitro antitumor test. Results showed that was more effective than inhibiting growth of cancer cells via suppressing expression VEGF, Cyclin A, B proteins a dose-dependent manner. Moreover, transgenic mice model vascular endothelial factor-A165 (hVEGF-A 165) gene-induced pulmonary...
Autologous platelet concentrates are currently widely used across different areas of regenerative medicine in order to enhance the wound healing process. Although several protocols for available, their application remains difficult due leading distinct products with vary potential biological uses. In this study, we attempted make a patch (PP) using mixtures rich plasma (PRP) injection and fibrin (PRF) promote repair regeneration. Experiments were performed full-thickness model mini-pigs....
Objective: To compare the healing results between platelet-rich plasma (PRP) and platelet-derived patches versus traditional advanced wound dressings in patients with chronic wounds. Method: Patients without diabetes were divided into two groups, each of which received either PRP patch treatments or dressings. All wounds cleaned, debrided assessed by physicians. The data analysed represented as mean ± standard deviation (SD). Student's t-test was used to calculate significance differences...
Influenza is an acute respiratory disease caused by the influenza virus which circulates annually in populations of different species. Madin-Darby Canine Kidney (MDCK) most widely utilized cell-line for conducting research. However, infectivity various strains MDCK cells not equivalent and productivity viral propagation also limited. We tested functional adequacy two MDCK-lineage cell lines, conventional MDCK/London, were evaluated assessing their with focus forming assays cellular toxicity...
Andrographolide is one of the major diterpene lactones found in Andrographis paniculata Nees and exhibits remarkable inhibitory effects on various cancers. In this study, antipulmonary cancer andrographolide were studied a lung tumor mouse model induced by human vascular endothelial growth factor<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:msub><mml:mi>A</mml:mi><mml:mrow><mml:mn>165</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>( hVEGF -<mml:math...
Chitosan and epidermal growth factor (EGF) have been shown to improve wound healing. This study investigates the healing effects of a spray solution (NewEpi, JoyCom Bio-Chem Co. Ltd., Taiwan) containing recombinant human EGF (rhEGF) delivered via newly patented technology-chitosan microencapsulated nanoparticles.On Wistar rats, two full-thickness wounds on dorsum bilateral spine were created. The rats randomised following treatment groups: hydrogel, wet dressing, foam, rhEGF spray+foam....
Background: Acute traumatic wounds are a common and distressing event for patients presenting to plastic surgery clinics. There no definitive conclusions regarding the benefits of collagen-based wound care products toward application on full-thickness compared traditional ointment or gauze care. In this clinical trial, we aimed define potential dressings healing through comparison composite with antibiotic dressings. Methods: This was randomized two-tailed controlled trial. The acute...
Treating diabetic wounds effectively remains a significant clinical challenge. Emerging studies suggest that microRNAs (miRNAs) play crucial roles in various physiological and pathological processes hold promise as therapeutic tools. This study investigates the miRNA expression profile keratinocytes using cell model of wounds. Microarray analysis revealed 43 miRNAs from wounded incubated under conditions (high glucose/hypoxia) exhibited two-fold change compared to those normal (low...