A5048482520- Global Maternal and Child Health
- Child Nutrition and Water Access
- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Maternal and Neonatal Healthcare
- Iron Metabolism and Disorders
- Birth, Development, and Health
- Neonatal Respiratory Health Research
- Hemoglobinopathies and Related Disorders
- Preterm Birth and Chorioamnionitis
- Global Public Health Policies and Epidemiology
- Pregnancy and Medication Impact
- Global Health Care Issues
- Bone health and osteoporosis research
- Reproductive Health and Contraception
- Cardiovascular Issues in Pregnancy
- Infant Development and Preterm Care
- Breastfeeding Practices and Influences
- COVID-19 Impact on Reproduction
- Child and Adolescent Health
- Gestational Diabetes Research and Management
- Bone health and treatments
- Healthcare Systems and Reforms
- Child Nutrition and Feeding Issues
Thomas Jefferson University
2016-2025
Wildlife Conservation Society Congo
2024
RTI International
2007-2024
Jawaharlal Nehru Medical College
2023
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2007-2023
Aga Khan University
2015-2023
Datta Meghe Institute of Medical Sciences
2023
Indiana University – Purdue University Indianapolis
2015-2023
Government Medical College
2023
Thomas Jefferson University Hospital
2021
Of the 3.7 million neonatal deaths and 3.3 stillbirths each year, 98% occur in developing countries. An evaluation of community-based interventions designed to reduce number these is needed.With use a train-the-trainer model, local instructors trained birth attendants from rural communities six countries (Argentina, Democratic Republic Congo, Guatemala, India, Pakistan, Zambia) World Health Organization Essential Newborn Care course (which focuses on routine care, resuscitation,...
Adolescent girls between 15 and 19 years give birth to around 16 million babies each year, 11% of births worldwide. We sought determine whether adolescent mothers are at higher risk maternal perinatal adverse outcomes compared with aged 20–24 in a prospective, population-based observational study newborn low resource settings. undertook multi-country research all pregnant women defined geographic areas across 7 sites six low-middle income countries (Kenya, Zambia, India, Pakistan, Guatemala...
Because large, prospective, population-based data sets describing maternal outcomes are typically not available in low- and middle-income countries, it is difficult to monitor mortality rates over time identify factors associated with mortality. Early identification of risk essential develop comprehensive intervention strategies preventing pregnancy-related complications. Our objective was describe a multi-country dataset determine maternal, pregnancy-related, delivery postpartum...
Objective To quantify maternal, fetal and neonatal mortality in low-and middle-income countries, to identify when deaths occur relationships between maternal stillbirths deaths.Methods A prospective study of pregnancy outcomes was performed 106 communities at seven sites Argentina, Guatemala, India, Kenya, Pakistan Zambia.Pregnant women were enrolled followed until six weeks postpartum.Findings Between 2010 2012, 214 070 220 235 (97.2%) completed follow-up.The ratio 168 per 100 000 live...
During the post-partum period, most women wish to delay or prevent future pregnancies. Despite this, unmet need for family planning up a year after delivery is higher than at any other time. This study aims assess fertility intention, contraceptive usage and amongst who are six weeks postpartum, as well identify those greatest risk of having an during this period. Using NICHD Global Network Women's Children's Health Research's multi-site, prospective, ongoing, active surveillance system...
Early initiation of breastfeeding after birth and exclusive through six months age confers many health benefits for infants; both are crucial high impact, low-cost interventions. However, determining accurate global rates these activities has been challenging. We use population-based data to describe: (1) early (defined as within 1 hour birth) at 42 days post-partum; (2) factors associated with failure initiate post-partum. Prospectively collected from women their live-born infants enrolled...
To describe the association of maternal anaemia with maternal, fetal, and neonatal outcomes.Prospective cohort study.Rural India Pakistan.Pregnant women residing in study catchment area.We performed an analysis a prospective pregnancy registry which haemoglobin is commonly obtained as well outcomes for 42 days post-delivery. Women 40 years or older who delivered before 20 weeks had level <3.0 g/dl were excluded. Our primary exposure was anaemia, categorised keeping World Health Organization...
Stillbirth rates remain nearly ten times higher in low-middle income countries (LMIC) than high countries. In LMIC, where 98% of stillbirths worldwide occur, few population-based studies have documented characteristics or care for mothers with stillbirths. Non-macerated stillbirths, those occurring around delivery, are generally considered preventable appropriate obstetric care. We undertook a prospective, observational study all pregnant women defined geographic areas across 7 sites...
Stillbirth rates remain high, especially in low and middle-income countries, where are 25 per 1000, ten-fold higher than high-income countries. The United Nations' Every Newborn Action Plan has set a goal of 12 stillbirths 1000 births by 2030 for all From population-based pregnancy outcome registry, including data from 2010 to 2016 two sites each Africa (Zambia Kenya) India (Nagpur Belagavi), as well Pakistan Guatemala, we evaluated the stillbirth annual decline risk factors 427,111 which...
Reported benefits of maternal nutrition supplements commenced during pregnancy in low-resource populations have typically been quite limited.This study tested the effects on newborn size, especially length, commencing for women ≥3 mo before conception (Arm 1), compared with same supplement late first trimester 2) or not at all (control Arm 3).Women First was a 3-arm individualized randomized controlled trial (RCT). The intervention lipid-based micronutrient supplement; protein-energy also...
Preterm birth continues to be a major public health problem contributing 75% of the neonatal mortality worldwide. Low weight (LBW) is an important but imperfect surrogate for prematurity when accurate assessment gestational age not possible. While there overlap between preterm and LBW newborns, those that are both premature at highest risk adverse outcomes. Understanding epidemiology prevention improved care in many countries, data sparse incomplete.We conducted analyses using Global...
Abstract Iron deficiency anemia (IDA) is common in many chronic diseases, and intravenous (IV) iron offers a rapid efficient correction. This trial compared the efficacy safety of isomaltoside (also known as ferric derisomaltose) sucrose patients with IDA who were intolerant of, or unresponsive to, oral iron. The was an open‐label, comparative, multi‐center trial. Five hundred eleven from different causes randomized 2:1 to followed for 5 weeks. cumulative dose based on body weight hemoglobin...
Despite a high frequency of iron deficiency in pregnancy, the United States Preventative Services Task Force (USPSTF) stated: “there is inconclusive evidence routine supplementation for anemia improves maternal or infant clinical health outcomes.” In contradistinction, high-quality epidemiologic studies report long lasting deficits infants diagnosed with first 6 months life compared who were not, specific cognition, memory, executive function and electrophysiology documented up to 19 years...
Abstract Iron deficiency anemia (IDA) is prevalent, and intravenous iron, especially if given in a single dose, may result better adherence compared with oral iron. The present trial (FERWON‐IDA) part of the FERWON program iron isomaltoside 1000/ferric derisomaltose (IIM), evaluating safety efficacy high dose IIM IDA patients mixed etiologies. This was randomized, open‐label, comparative, multi‐center conducted USA. were randomized 2:1 to 1000 mg IIM, or sucrose (IS) administered as 200...
Abstract Background Pakistan has among the poorest pregnancy outcomes worldwide, significantly worse than many other low-resource countries. The reasons for these differences are not clear. In this study, we compared in to countries and explored factors that might help explain differences. Methods Global Network (GN) Maternal Newborn Health Registry (MNHR) is a prospective, population-based observational study includes all pregnant women their defined geographic communities six low-middle...