- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Hydrogels: synthesis, properties, applications
- Bone Tissue Engineering Materials
- Silk-based biomaterials and applications
- Tissue Engineering and Regenerative Medicine
- Orthopaedic implants and arthroplasty
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Nanoparticle-Based Drug Delivery
- Titanium Alloys Microstructure and Properties
- Micro and Nano Robotics
- Bone health and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Periodontal Regeneration and Treatments
- Gold and Silver Nanoparticles Synthesis and Applications
- Polysaccharides and Plant Cell Walls
- Xenotransplantation and immune response
- 3D Printing in Biomedical Research
Northwestern Polytechnical University
2023-2025
Air Force Medical University
2024
Beijing Shijitan Hospital
2022
Capital Medical University
2022
University of South China
2021-2022
Third Affiliated Hospital of Sun Yat-sen University
2019
Sun Yat-sen University
2019
The capsule robot (CR) is a promising endoscopic method in gastrointestinal diagnosis because of its low discomfort to users. Most CRs are used acquire image information only and lack the ability collect samples. Although some biopsy robots (BCRs) have been developed, it remains challenging intestinal tissue while avoiding tearing adhesion due flexibility colonic tissue. In this study, we develop BCR with novel sampling strategy which soft scratched sharp blades rotating at high speed avoid...
<title>Abstract</title> <bold>Background </bold>Diabetic wound infections, exacerbated by multidrug-resistant pathogens like MRSA, remain a critical challenge due to biofilm persistence and dysregulated oxidative-inflammatory-metabolic crosstalk. <bold>Results </bold>In this work, we engineered COG-Z@P200 hydrogel, chitosan-based hydrogel integrating polydopamine-coated ZIF-8 nanoparticles, synergize mild photothermal therapy (40–45°C) with metabolic-immune reprogramming. Upon NIR...
Abstract Compared with water‐soluble osteogenic drugs, fat‐soluble drugs exhibit higher bioavailability and drug stability, making them valuable for enhancing the osseointegration of implants. However, existing drug‐loading coatings are primarily designed limiting their effectiveness in loading delivering drugs. This study employed alkali treatment, silanization, oleic acid acylation to sequentially modify surface Ti alloy, aiming fabricate surfaces capable efficiently Results show that...
This research was set up to determine the efficacy of a synthetic biomimetic skin substitute poly-L-lactide (PLLA)/gelatin nanofiber membrane in facilitating chronic cutaneous wound healing. The material physical properties and biological characteristics were evaluated. safety effectiveness further confirmed by clinical applications. Results indicated that average diameter nano pores 0.65 μm. mean contact angle 80.39°, tensile strength 4.42 ± 0.43 MPa. proliferation fibroblasts monocytes...
Objective: The purpose of this study was to improve the performance decellularized renal scaffolds by genipin crosslinking method facilitate regeneration tissues and cells provide better conditions for repair defective kidneys. Methods: SD rats were randomly divided into three groups: normal group, uncrosslinked scaffold group genipin-crosslinked group. Hematoxylin eosin, Masson immunofluorescence staining used observe histomorphological characteristics kidneys in each preservation vascular...
In addition to transmitting and carrying genetic information, RNA plays an important abiotic role in the world of nanomaterials. is a natural polyanionic biomacromolecule, its ability promote osteogenesis by binding with other inorganic materials as osteogenic induction agent was discovered only recently. However, whether it can osseointegration on implants has not been reported. Here, we investigated effect RNA-containing coating peri-implant osseointegration. Total extracted from rat...
Abstract Background Skin plays an important role in preventing the invasion of disease-causing microorganisms. However, when skin is damaged, damaged area vulnerable to by bacteria and other harmful microorganisms, leading infection wound. Methods Here, this paper reported a self-healing, antibacterial, antioxidant multifunctional hydrogel that accelerated healing infected wounds releasing curcumin. The internal structure, cell compatibility, anti-oxidation, antibacterial properties were...