Yicheng Chen

ORCID: 0000-0003-2433-9554
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About
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Research Areas
  • Bone Tissue Engineering Materials
  • RNA Interference and Gene Delivery
  • Orthopaedic implants and arthroplasty
  • Spine and Intervertebral Disc Pathology
  • Crystallization and Solubility Studies
  • Drug Solubulity and Delivery Systems
  • Spondyloarthritis Studies and Treatments
  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • Advanced Nanomaterials in Catalysis
  • Immunotherapy and Immune Responses
  • Graphene and Nanomaterials Applications
  • Bone health and treatments
  • Photoreceptor and optogenetics research
  • Advanced biosensing and bioanalysis techniques
  • Titanium Alloys Microstructure and Properties
  • Osteoarthritis Treatment and Mechanisms
  • Skin Protection and Aging
  • Analytical Chemistry and Chromatography
  • Nanoplatforms for cancer theranostics

Air Force Medical University
2024

Tongren Hospital
2024

Shanghai Jiao Tong University
2024

Henan Institute of Science and Technology
2015

Nankai University
2006

There is still a lack of high-level evidence regarding the causal relationship between smoking and intervertebral disc degenerative diseases. This study utilized data from genome wide analysis studies conducted two-sample Mendelian randomization analyses across multiple heterogeneous datasets. We evaluated relationships behavior, serum inflammatory factors, chemokines, degeneration. Sensitivity was performed to examine heterogeneity pleiotropy effects. The results indicated that smokers were...

10.1016/j.heliyon.2024.e37044 article EN cc-by Heliyon 2024-08-28

Abstract Compared with water‐soluble osteogenic drugs, fat‐soluble drugs exhibit higher bioavailability and drug stability, making them valuable for enhancing the osseointegration of implants. However, existing drug‐loading coatings are primarily designed limiting their effectiveness in loading delivering drugs. This study employed alkali treatment, silanization, oleic acid acylation to sequentially modify surface Ti alloy, aiming fabricate surfaces capable efficiently Results show that...

10.1002/adfm.202314005 article EN Advanced Functional Materials 2024-01-18

Abstract Tissue‐engineered extraction products, such as apoptotic extracellular vesicles (ApoEVs), significantly promote tissue regeneration, endowing them with the potential to improve osseointegration. However, there is an urgent need determine how effectively load these materials onto a material surface maximize their function. Considering that all products have phospholipid bilayer, phospholipid‐modified implant coating designed can tissue‐engineered bilayer structure. ApoEVs are loaded...

10.1002/admi.202400146 article EN Advanced Materials Interfaces 2024-05-09

Purpose: To study the inclusion mechanism and heat stability of complex formed between 4'- hydroxychalcone hydroxypropyl-β-cyclodextrin (HP-β-CD) Methods: The 4'-hydroxychalcone HP-β-CD was investigated by phase solubility method. physicochemical properties were evaluated Fourier transform infrared spectroscopy (FT-IR) x-ray diffractometry (XRD) while measured thermogravimetric/differential scanning calorimetry (TG/DSC).Results: constants complexes higher than those β-CD at all temperatures....

10.4314/tjpr.v13i12.3 article EN cc-by Tropical Journal of Pharmaceutical Research 2015-01-09

In addition to transmitting and carrying genetic information, RNA plays an important abiotic role in the world of nanomaterials. is a natural polyanionic biomacromolecule, its ability promote osteogenesis by binding with other inorganic materials as osteogenic induction agent was discovered only recently. However, whether it can osseointegration on implants has not been reported. Here, we investigated effect RNA-containing coating peri-implant osseointegration. Total extracted from rat...

10.1021/acsbiomaterials.4c00133 article EN cc-by-nc-nd ACS Biomaterials Science & Engineering 2024-06-29
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