A5046155086- Hydrogels: synthesis, properties, applications
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Drug Solubulity and Delivery Systems
- Nanoparticle-Based Drug Delivery
- 3D Printing in Biomedical Research
- Proteoglycans and glycosaminoglycans research
- Date Palm Research Studies
- Diet, Metabolism, and Disease
- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Diet and metabolism studies
- Ophthalmology and Visual Impairment Studies
- Synthesis and properties of polymers
- Nanoplatforms for cancer theranostics
- Analytical Methods in Pharmaceuticals
- Coffee research and impacts
- Advanced Nanomaterials in Catalysis
- Analytical Chemistry and Chromatography
- Vitamin D Research Studies
- Natural Antidiabetic Agents Studies
- Genetic and Environmental Crop Studies
- Drug-Induced Hepatotoxicity and Protection
- Piperaceae Chemical and Biological Studies
- Urological Disorders and Treatments
Kaohsiung Medical University
2020-2025
Zhejiang Sci-Tech University
2024-2025
University of Agriculture Faisalabad
2024-2025
Jinnah Medical & Dental College
2023
Allama Iqbal Medical College
2022-2023
Post Graduate Medical Institute
2023
Mangalore Institute of Oncology
2023
King Edward Medical University
2019-2023
Islamia University of Bahawalpur
2019-2023
Indira Gandhi Government Medical College & Hospital
2023
The aim of the current research work was to prepare Car934-g-poly(acrylic acid) hydrogels by free-radical polymerization technique. Various concentrations carbopol, acrylic acid and ethylene glycol dimethacrylate were employed for fabrication hydrogels. Fourier-transform infrared spectroscopy (FTIR), Thermogravimetric analysis (TGA), Differential scanning calorimetry (DSC), Scanning electron microscope (SEM) Powder X-ray diffractometry (PXRD) studies performed know structural arrangement,...
The aim of the current study was to fabricate naturally derived polymer based hydrogels for controlled release diclofenac sodium (DS) a long duration time. In this research work, alginate-co-poly(2-acrylamido-2-methyl propane sulphonic acid) (SA-co-poly(AMPS)) were prepared by free radical polymerization technique, where alginate (SA) and 2-acrylamido-2-methyl acid (AMPS) used as monomer while ammonium peroxodisulfate (APS) N,N′-Methylene bisacrylamide (MBA) initiator cross-linker,...
The aim of the current study was to prepare pH-sensitive chondroitin sulfate-co-poly(acrylic acid) hydrogels (CSPAA-hydrogels) for controlled release diclofenac sodium. CSPAA-hydrogels were prepared by free radical polymerization technique where sulfate (CS) used as polymer; ethylene glycol dimethylacrylate (EGDMA) and acrylic acid (AA) cross-linker monomer. Various structural features evaluated FTIR, XRD, TGA, DSC, SEM, which confirmed synthesis stability developed structures. FTIR studies...
Poor solubility is an ongoing issue and the graph of poorly soluble drugs has increased markedly which critically affect their dissolution, bioavailability, clinical effects. This common needs to be addressed, for this purpose a series polyethylene glycol (PEG-4000) based nanogels were developed by free radical polymerization technique enhance solubility, bioavailability drug meloxicam (MLX), as improved significant application nanosystems. Developed formulations characterized FTIR, XRD,...
In the current research work, pH-sensitive hydrogels were prepared via a free radical polymerization technique for targeted delivery of 5-aminosalicylic acid to colon. Various proportions chitosan, β-Cyclodextrin, and acrylic cross-linked by ethylene glycol dimethacrylate. Ammonium persulfate was employed as an initiator. The development new polymeric network successful encapsulation drug confirmed Fourier transform infrared spectroscopy. Thermogravimetric analysis indicated high thermal...
The objective of this study is to design a polymeric network nanogels for sustained release caffeine. Therefore, alginate-based were fabricated by free-radical polymerization technique the delivery Polymer alginate was crosslinked with monomer 2-acrylamido-2-methylpropanesulfonic acid crosslinker N',N'-methylene bisacrylamide. prepared subjected sol-gel fraction, polymer volume swelling, drug loading, and studies. A high gel fraction seen increasing feed ratio polymer, monomer, crosslinker....
Madecassoside, a triterpenoid saponin compound mainly isolated from the gotu kola herb (Centella asiatica), shows an extensive range of biological activities, including antiapoptotic, antioxidant, anti-inflammatory, moisturizing, neuroprotective, and wound healing effects. It has been highly used in management eczema, skin wounds, other diseases. Due to poor oral bioavailability, membrane permeability, intestinal absorption, clinical application madecassoside is limited. Hence, drug carrier...
SUMMARY BACKGROUND No definitive treatment exists for Coronavirus Disease 2019 (COVID-19). Honey and Nigella sativa (HNS) have established antiviral, antibacterial, anti-inflammatory immunomodulatory properties. Hence, we investigated efficacy of HNS against COVID-19. wide METHODS We conducted a multicenter, placebo-controlled, randomized clinical trial at 4 centers in Pakistan. RT-PCR confirmed COVID-19 adults showing moderate or severe disease were enrolled the study. Patients presenting...
Different combinations of polymers, aspartic acid (ASP), alginic (AL), and monomer acrylic (AA) were crosslinked in the presence an initiator ammonium peroxodisulfate (APS) cross-linker ethylene glycol dimethacrylate (EGDMA) to develop acid/alginic acid-co-poly(acrylic acid) (ASP/ALPAA) (semi-interpenetrating polymer network (SIPN)) hydrogels by free radical polymerization technique for controlled delivery ibuprofen (IBP). Various studies such as dynamic swelling studies, drug loading, vitro...
This study investigates pH-sensitive hydrogels based on biocompatible, biodegradable polysaccharides and natural polymers such as chondroitin sulfate alginate in combination with synthetic monomer acrylic acid, controlled drug carriers. Investigations were conducted for sulfate/alginate-graft-poly(acrylic acid) hydrogel various mixing ratios of sulfate, acid the presence ammonium persulfate N',N'-Methylene bisacrylamide. Crosslinking loading confirmed by Fourier transform infrared...
Smart and intelligent xanthan gum/pluronic F-127 hydrogels were fabricated for the controlled delivery of atomoxetine HCl. Different parameters such as DSC, TGA, FTIR, XRD, SEM, drug loading, porosity, swelling index, release, kinetics modeling appraised prepared matrices hydrogels. FTIR confirmed successful synthesis hydrogel, while TGA DSC analysis indicated that thermal stability reagents was improved after polymerization technique. SEM revealed hard surface XRD a reduction in...
The objective of the current study work was to fabricate sodium poly(styrene sulfonate-co-poly acrylic acid) (SPSPAA) hydrogels by using a free radical co-polymerization method for controlled delivery ketorolac tromethamine (KT). Polymer (sodium sulfonate) (SPS) polymerized with monomer acid (AA) in presence initiator ammonium peroxodisulfate (APS) and cross-linker N′,N′-Methylene bisacrylamide (MBA). Different combinations polymer, monomer, were employed development polymeric hydrogels....
Objective of the research was to potentiate solubility Rosuvastatin by nanogels synthesized free radical polymerization. Surface morphology and structural compatibility were studied through scanning electron microscopy (SEM) Fourier Transform Infrared (FTIR) spectroscopy. Zeta sizer used for particle size analysis. Swelling, in-vitro release studies accomplished in different media. Similarly, results commercially available tablets compared dissolution Biocompatibility study performed healthy...
External factors often lead to predictable damage, such as chemical injuries, burns, incisions, and wounds. Bacterial resistance antibiotics at wound sites underscores the importance of developing hydrogel composite systems with inorganic nanoparticles possessing antibacterial properties treat infected wounds expedite skin regeneration process. In this study, a promising TiO2-HAp@PF-127@CBM organic integrated system was designed address challenges associated bacterial healing. The...