- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Cystic Fibrosis Research Advances
- Ear and Head Tumors
- Bone Tumor Diagnosis and Treatments
- Neonatal Respiratory Health Research
- Genetic and Kidney Cyst Diseases
- Olfactory and Sensory Function Studies
- Transplantation: Methods and Outcomes
- Salivary Gland Tumors Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Asthma and respiratory diseases
- Teratomas and Epidermoid Cysts
- Cleft Lip and Palate Research
- Sharing Economy and Platforms
- Pelvic floor disorders treatments
- Urinary Tract Infections Management
- Leadership, Behavior, and Decision-Making Studies
- Financial Literacy, Pension, Retirement Analysis
- Advances in Oncology and Radiotherapy
- Cognitive Abilities and Testing
- Tracheal and airway disorders
- Biochemical Analysis and Sensing Techniques
- Congenital Ear and Nasal Anomalies
- COVID-19 and Mental Health
The University of Western Australia
2024
University of Arkansas for Medical Sciences
2024
University of Pennsylvania
2020-2023
Hospital of the University of Pennsylvania
2022
University of Copenhagen
2015-2022
Copenhagen University Hospital
2016-2022
Mayo Clinic in Arizona
2017-2019
Stanford University
2017-2019
Cleveland Clinic
2017
Zealand University Hospital Køge
2015-2017
In a recent meta-analysis, financial literacy – understanding basic terms and concepts was significantly correlated with general intelligence (r ≈ 0.62). However, this correlation may be underestimated, as few studies employed robust measures of both (more than one subtest) (>12 items). Additionally, cognitive reflection has not been investigated for its unique capacity at predicting literacy, an important consideration, suggested to measure cognition. Beyond factors, non-cognitive...
Bitter and sweet taste receptors are present in the human upper airway, where they have roles innate immunity. Previous studies shown that 1 of 25 bitter receptors, TAS2R38, responds to specific bacterial signaling molecules evokes type a defense response whereas ligands suppress other types responses.We examined whether might also be involved immunity by using sensory responses compounds not TAS2R38 (quinine denatonium benzoate) assess sensitivity chronic rhinosinusitis (CRS) patients. CRS...
Abstract Objectives The use of topical corticosteroids to manage postoperative sinonasal symptoms after endoscopic skull base surgery (ESBS) has not been well studied. We quantified long‐term impact steroid irrigations (SIs) on quality life patients ESBS. Methods Retrospective review at the University Pennsylvania undergoing ESBS from 2010 2019. Data patient demographics and treatment with nasal saline irrigation twice daily without dissolved steroids (mometasone or budesonide) was...
Background Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without (CRSsNP), aspirin‐exacerbated respiratory disease (AERD) have varying levels of inflammation severity. Solitary chemosensory cells (SCCs) are enriched in polyps, the primary source interleukin 25 (IL‐25) upper airways, leading to type 2 inflammation, activated by bitter‐tasting denatonium benzoate (DB). Thus, we sought evaluate DB taste perception at a range concentrations order identify 1 that most...
Aspirin-exacerbated respiratory disease (AERD) is optimally managed by endoscopic sinus surgery (ESS) followed aspirin therapy after desensitization (ATAD). Most AERD quality of life (QOL) studies use the 22-item Sinonasal Outcomes Test (SNOT-22), which focuses predominantly on sinonasal outcomes.This study seeks to assess QOL outcomes in patients ESS and ATAD via 12-item Short Form Survey (SF-12), a well-validated measure for general health status chronic conditions.Retrospective review 112...
Background: We examined the association of adult lung transplant candidates’ self-reported affect with transplant-related outcomes, evaluating whether a positive (vs negative) frame mind might be protective. Method: Consenting waitlisted candidates from 6 centers completed questionnaires including Positive and Negative Affect Schedule annually posttransplant. Univariate logistic regression analysis was performed to determine baseline outcomes death or delisting. Models were subsequently...
Key Clinical Message Subdural empyema is a rare but potentially life‐threatening complication to sinusitis. Awareness of infection and early diagnosis the essence when dealing with putatively immunosuppressed patient. Furthermore, patients at increased risk infections due immunosuppression need be fully informed risks associated their treatment.
<b>Background:</b> The airway epithelium eliminates inhaled pathogens adhered to the mucus layer by directional motility of cilia. This vital mechanism is defective in primary ciliary dyskinesia (PCD) and cystic fibrosis (CF). Although disorders are monogenic each individual, we speculate that disrupted expression or function certain proteins also drives disease phenotypes. Among interest, selected intraflagellar transport protein 88 (IFT88) for assessment given its key role cilia assembly...
Introduction: Use of steroid irrigation in management chronic rhinosinusitis (CRS) after endoscopic sinus surgery (ESS) suggests improved outcomes.[1] However, literature regarding postoperative ESS for inverted papilloma (IP), is less clear.[2] Currently, there discrepancy on the usage nasal saline rinses versus optimizing long-term patient quality life (QoL) IP resection. This study analyzed post-operative outcomes to determine optimal with regard type patients IP.
Objectives: Inverted papilloma (IP) is a benign but locally destructive tumor in the sinonasal cavity. Treatment of IP consists surgical resection with endoscopic sinus surgery (ESS). Patients type II diabetes mellitus (DMII) are known to have systemic manifestations their disease, including poor wound healing after surgery. The Sinonasal Outcomes Test (SNOT-22) validated tool assess patient quality life and burden symptoms from disease. goal this study was compare postoperative life, based...
Objective: Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by the presence of both subjective and objective evidence sinonasal inflammation persisting for greater than 12 weeks. CRSwNP often associated development inverted papilloma (IP), which are benign, but locally destructive, tumors that may originate in cavity or paranasal sinuses. Surgical resection treatment choice IP. The role influencing quality life after surgical IP has not been previously elucidated. goal this...
Introduction: Sinonasal inverted papilloma (IP) is a benign but locally aggressive neoplasm. Diagnosis of IP consists computed tomography (CT) and nasal endoscopy findings while treatment surgical resection.[1] Lund Mackay (LM) scores are commonly used staging system to quantify severity sinus disease on CT imaging. It has been proposed that score ≥ 4 suggests higher probability for ≤ 3 lower disease.[2] Patients scoring greater than often candidates surgery.[3] The 22-question Outcome Test...
Objective: Inverted papilloma (IP) is a benign tumor that originates in the sinonasal tract and often locally aggressive. Treatment of IP consists surgical resection with endoscopic sinus surgery (ESS). Infection represents potential postoperative complication prophylactically managed systemic antibiotics. The goal this study to determine if addition antibiotic nasal irrigations medical regimen will improve patient quality life, as measured by Sinonasal Outcome Test (SNOT 22).