A5080211133- Porphyrin and Phthalocyanine Chemistry
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal-Catalyzed Oxygenation Mechanisms
- Crystallography and molecular interactions
- Surface Chemistry and Catalysis
- Electrocatalysts for Energy Conversion
- Magnetism in coordination complexes
- Porphyrin Metabolism and Disorders
- Photodynamic Therapy Research Studies
- Photosynthetic Processes and Mechanisms
- Photochemistry and Electron Transfer Studies
- Electrochemical Analysis and Applications
- Metal complexes synthesis and properties
- CO2 Reduction Techniques and Catalysts
- Nanoplatforms for cancer theranostics
- Oxidative Organic Chemistry Reactions
- Luminescence and Fluorescent Materials
- Electrochemical sensors and biosensors
- Advanced battery technologies research
- Fluorine in Organic Chemistry
- Cyclopropane Reaction Mechanisms
- Metalloenzymes and iron-sulfur proteins
- Molecular Junctions and Nanostructures
- Advanced Photocatalysis Techniques
Technion – Israel Institute of Technology
2016-2025
University of Haifa
2015-2019
Hebrew University of Jerusalem
2004-2016
Freie Universität Berlin
2016
Bar-Ilan University
1989-2015
California Institute of Technology
2000-2012
Tel Aviv University
1999-2011
Beckman Research Institute
2011
Israel Institute
2008-2010
Stanford Synchrotron Radiation Lightsource
2009
The solvent-free, catalyst-free condensation of pyrrole and aldehydes provides an extremely facile synthetic pathway to novel corroles [Eq. (1); Ar=C6 F5 , 2,6-F2 C6 H3 2,6-Cl2 ]. product containing pentafluorophenyl groups is excellent precursor other derivatives, including ionic, water-soluble corrole.
Abstract Corroles display distinctive structural, spectroscopic, and photophysical properties, as well some exceptional chemical reactivities that are not shared by other molecules. In addition, low‐valent metal complexes extremely reactive when chelated corroles the opposite holds for high‐valent counterparts. One aim of this account is to provide a thorough understanding underlying principles govern these phenomena, while goal demonstrate how features may be used advantageously utilization...
If porphyrins can do it corroles better! The relatively stable (oxo)manganese(V) corrole 2 be characterized by spectroscopic methods following its ready formation from [Mn(tpfc)] (1, H3(tpfc)=5,10,15-tris(pentafluorophenyl)corrole). Complex 1 is a mild catalyst for the epoxidation of styrene iodosylbenzene.
An extremely simple biomimetic oxidation system, consisting of mixing metal complexes amphiphilic corroles with serum albumins, utilizes hydrogen peroxide for asymmetric sulfoxidation in up to 74% ee. The albumin-conjugated manganese also display catalase-like activity, and mechanistic evidence points toward oxidant-coordinated manganese(III) as the prime reaction intermediate.
The germanium(IV), tin(IV). and phosphorus(v) complexes of tris(pentafluorophenyl)corrole were prepared investigated by electrochemistry for elucidation the electrochemical HOMO-LUMO gap corrole spectroscopic characteristics pi radical cation. This information was found to be highly valuable assigning oxidation states in various iron corroles that prepared. Two rhodium(I) complex an N-substituted fully characterized X-ray crystallography all transition metal examined as cyclopropanation...
The solvent-free condensation of pyrrole and pentafluorobenzaldehyde (and to a lesser extent other electron-poor aldehydes as well) leads variety products, which three have been isolated fully characterized. two main products (11% each) are an open-chain pentapyrrole corrole, tetrapyrrolic macrocycle.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and Reactivity of Oxoiron(IV) PorphyrinsJohn T. Groves, Zeev Gross, Michael K. SternCite this: Inorg. Chem. 1994, 33, 22, 5065–5072Publication Date (Print):October 1, 1994Publication History Published online1 May 2002Published inissue 1 October 1994https://pubs.acs.org/doi/10.1021/ic00100a035https://doi.org/10.1021/ic00100a035research-articleACS PublicationsRequest reuse permissionsArticle Views1190Altmetric-Citations217LEARN ABOUT...
The role of cobalt and iron corroles in catalytic CO2 reduction has been studied. Chemical, electrochemical, photochemical reductions the stable metal Ph3PCoIII(tpfc) (tpfc = 5,10,15-tris(pentafluorophenyl)corrole), ClFeIV(tpfc), ClFeIV(tdcc) (tdcc 5,10,15-tris(2,6-dichlorophenyl)corrole) have carried out acetonitrile solutions. Stepwise to [MII(tpfc)]- [MI(tpfc)]2- states was observed all cases. Gradual with sodium amalgam permitted recording optical absorption spectra various oxidation...
On pyrrole! The pyrrole-based corrole ligands can offer an alternative to porphyrin systems. manganese corroles 1–4 are readily synthesized, undergo metal- not ligand-based redox chemistry, and 4 in particular shows impressive catalytic activity the oxygenation of styrene with iodosylbenzene.
The feasibility of a hydrogen-based economy relies very much on the availability catalysts for hydrogen evolution reaction (HER) that are not based Pt or other noble elements. Significant breakthroughs have been achieved with certain first row transition metal complexes in terms low overpotentials and large turnover rates, but majority reported work utilized purified deoxygenated solvents (most commonly mixtures organic solvents/acids). Realizing design earth abundant operate under truly...
Sulfonated gallium(III) corroles are intensely fluorescent macrocyclic compounds that spontaneously assemble with carrier proteins to undergo cell entry. We report in vivo imaging and therapeutic efficacy of a tumor-targeted corrole noncovalently assembled heregulin-modified protein directed at the human epidermal growth factor receptor (HER). Systemic delivery this protein-corrole complex results tumor accumulation, which can be visualized owing red fluorescence. Targeted leads death while...
The photophysical properties of Ir(III) corroles differ from those phosphorescent porphyrin complexes, cyclometalated and polyimine compounds, other luminescent metallocorroles. corrole phosphorescence is observed at ambient temperature wavelengths much longer (>800 nm) than most phosphors. solvatochromic behavior Ir(III)-corrole Soret Q absorption bands suggests that the lowest singlet excited states (S2 S1) are substantially more polar ground state.
The proton-activating intermediate in the cobalt corrole catalyzed hydrogen evolution reaction was characterized and a surprising effect of macrocycle halogenation uncovered.
Abstract Recent work has highlighted the potential of metallocorroles as versatile platforms for development drugs and imaging agents, since bioavailability, physicochemical properties therapeutic activity can be dramatically altered by metal ion substitution and/or functional group replacement. Significant advances in cancer treatment have been reported based on with a water-soluble bis-sulfonated gallium corrole both cellular rodent-based models. We now show that cytotoxicities increase...
Abstract The future of affordable fuel cells strongly relies on the design earth‐abundant (non‐platinum) catalysts for electrochemical oxygen reduction reaction (ORR). However, bottleneck in overall process occurs therein. We have examined herein trivalent Mn, Fe, Co, Ni, and Cu complexes β‐pyrrole‐brominated corrole as ORR catalysts. adsorption these a high‐surface‐area carbon powder (BP2000) created unique composite material, used measurements acidic aqueous solutions. These experiments...
A series of five free-base corroles were metalated and brominated to form 10 manganese(III) corroles. Two the six analyzed by X-ray crystallography, including one complex that may be considered a transition-state analogue oxygen atom transfer (OAT) from (oxo)manganese(V) thioansisole. Oxidation ozone allowed for isolation corresponding corroles, whose characterization 1H 19F NMR spectroscopy electrochemistry revealed low-spin triply bound manganese−oxygen moiety. Mechanistic insight was...
Abstract Corrole complexes with gold(I) and gold(III) were synthesized their structural, photophysical, electrochemical properties investigated. This work includes the X‐ray crystallography characterization of complexes, both chelated by a corrole fully brominated β‐pyrrole carbon atoms. The mononuclear chiral appears to be first its kind within porphyrinoid family, while most unique property is that it displays phosphorescence at ambient temperatures.
Fuel cells are considered as the only viable solution for long-range electromobility, but very rare and expensive platinum is currently required catalyzing bottleneck reaction therein: oxygen reduction. Within search catalysts that not based on precious metals, cobalt corroles were uncovered to fulfill requirements of high selectivity low overpotential. We now report electropolymerization a specifically designed catalyst, cobalt(III) complex tris(4-aminophenyl)corrole, upon which 3D...
Designing catalysts that are not based on precious metals remains a major research priority worldwide, particularly for the feasible production of hydrogen gas. Given increasing interest in metallocorroles as electrocatalysts, three nickel corroles were explored evolution reaction (HER) current study. The precatalysts fully characterized square planar d8 nickel(II) coordination compounds which extra negative charge is stabilized by electron-withdrawing substituents corrole and robust...
High quantum yields are found for the prototype metallocorrole 1, which is readily prepared from GaCl3 and tris(pentafluorophenyl)corrole. The crystallographic electronic structures of 1 reported as well simple generation its π-cation radical complex by chemical oxidation characteristic spectroscopic features this ion.