G N Zhang

ORCID: 0000-0003-1189-724X
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About
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Research Areas
  • Colorectal Cancer Surgical Treatments
  • Colorectal and Anal Carcinomas
  • Clinical practice guidelines implementation
  • Gastric Cancer Management and Outcomes
  • Nanoparticle-Based Drug Delivery
  • Abdominal Trauma and Injuries
  • Congenital Anomalies and Fetal Surgery
  • Health Systems, Economic Evaluations, Quality of Life
  • Cancer Cells and Metastasis
  • Extracellular vesicles in disease
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cancer Research and Treatments
  • Nanoplatforms for cancer theranostics
  • Congenital Diaphragmatic Hernia Studies
  • Intestinal Malrotation and Obstruction Disorders
  • Metastasis and carcinoma case studies
  • Radiomics and Machine Learning in Medical Imaging
  • 3D Printing in Biomedical Research
  • Hepatocellular Carcinoma Treatment and Prognosis

Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2025

Peking Union Medical College Hospital
2019-2025

Shanghai University of Traditional Chinese Medicine
2025

Seventh People's Hospital of Shanghai
2025

Jilin University
2023

Union Hospital
2023

Objective: To compare the impact of different treatment strategies on survival outcomes in rectal cancer patients with poor response to neoadjuvant therapy, and explore survival-related influencing factors. Methods: A retrospective cohort study was conducted. Between January 2018 November 2022, clinical, pathological, follow-up data 106 who received therapy were evaluated as grade 4 or 5 based Magnetic Resonance Tumor Regression Grade (mrTRG) from database at Peking Union Medical College...

10.3760/cma.j.cn441530-20240323-00108 article EN PubMed 2025-01-25

Angiogenesis in tumors is imperative to tumor growth. Our previous studies revealed that herb-partitioned moxibustion (HPM) could delay colitis-associated cancer (CAC), but the mechanism of effects on angiogenesis remains largely undiscovered. We aimed investigate whether HPM delays CAC by inhibiting with emergent three-dimensional (3D) imaging technologies. The model was induced azoxymethane (AOM)/dextran sodium sulphate (DSS). rats were randomly divided into normal, and groups....

10.2147/jir.s518214 article EN cc-by-nc Journal of Inflammation Research 2025-05-01

Sonodynamic therapy (SDT), with its high tissue penetration and noninvasive advantages, represents an emerging approach to eradicating solid tumors. However, the outcomes of SDT are typically hampered by low oxygen content immunosuppression in tumor microenvironment (TME). Accordingly, we constructed a cascade nanoplatform regulate TME improve anti-tumor efficiency SDT.In this study, rationally design incorporating immunostimulant hyaluronic acid (HA) sonosensitizer chlorin e6 (Ce6) on...

10.2147/ijn.s431221 article EN cc-by-nc International Journal of Nanomedicine 2023-11-01

Objective: To examine the ultrasound features and clinical characteristics of intestinal ischemia secondary to acute mesenteric venous thrombosis (AMVT). Methods: From January 2016 June 2019, 11 patients were diagnosed as AMVT confirmed by surgical pathology or CT in Peking Union Medical College Hospital. The included 7 males 4 females, aging (52.8±11.9) years (range: 34 81 years).The characters retrospectively reviewed. Results: Abdomen pain was chief complaint all patients. Other...

10.3760/cma.j.cn112139-20200330-00268 article EN PubMed 2020-11-01

The aim of this study was to evaluate the impact neoadjuvant radiotherapy on anorectal function patients with mid-low rectal cancer by means high-resolution manometry.

10.3760/cma.j.cn441530-20230920-00097 article EN PubMed 2024-01-25

To explore the impact on safety and prognosis in patients with right-sided colon cancer participating surgical clinical research.

10.3760/cma.j.cn441530-20240129-00048 article EN PubMed 2024-09-25

Objective: The aim of the current study is to compare short-term clinical outcomes between Billroth-I reconstruction using an overlap method and delta-shaped anastomosis in totally laparoscopic distal gastrectomy (TLDG). Method: A retrospective cohort was performed. following inclusion criteria were applied: (1) Preoperative gastroscopy CT confirmed that tumor located antrum stomach, biopsy suggested adenocarcinoma; (2) Chest, abdomen pelvis enhanced showed no evidence distant metastasis;...

10.3760/cma.j.issn.1671-0274.2019.11.010 article EN PubMed 2019-11-25

Conventional tumor culture models include two-dimensional cell cultures and xenograft models. The former has disadvantages including lack of heterogeneity poor clinical relevance, while the latter are limited by slow growth, low engraftment successful rate, high cost. In recent years, in vitro three-dimensional (3D) have emerged as tool to better recapitulate spatial structure vivo environment tumors. addition, they preserve pathological genetic features cells reflect complex intracellular...

10.3760/cma.j.cn112152-20220928-00661 article EN PubMed 2023-06-23

Objective: To analyze the ultrasound characteristics of small bowel volvulus among adults and to investigate value in diagnosis volvulus. Methods: Totally 34 with confirmed by clinical or surgery who underwent examination at Peking Union Medical College Hospital from August 2017 October 2022 were enrolled, including 19 males 15 females, aged (55.0±21.8) years (range: 94 years). The characteristics, CT images patients retrospectively reviewed, ultra, sound features its diagnostic efficacy...

10.3760/cma.j.cn112139-20230309-00098 article EN PubMed 2023-10-01

To examine the prognosis factors of postoperative cardiac complications in colorectal cancer patients co-morbidated with coronary artery disease.

10.3760/cma.j.cn112139-20211230-00627 article EN PubMed 2022-06-28
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