A5019472670- Dermatologic Treatments and Research
- Cancer Immunotherapy and Biomarkers
- RNA modifications and cancer
- interferon and immune responses
- Acne and Rosacea Treatments and Effects
- Skin and Cellular Biology Research
- Cancer-related molecular mechanisms research
- Cancer Genomics and Diagnostics
- Immunotherapy and Immune Responses
- Dermatology and Skin Diseases
- Systemic Sclerosis and Related Diseases
North China University of Science and Technology
2021-2025
Abstract Rosacea is a chronic inflammatory skin disorder that can lead to fibrosis. However, the mechanisms underlying fibrosis in later stages of rosacea have been less thoroughly investigated. Interleukin‐17A (IL‐17A) has implicated both inflammation and organ fibrosis; however, effectiveness mechanism IL‐17A‐neutralizing antibodies rosacea‐related remain unclear. In this study, we induced rosacea‐like lesions mice using LL‐37 administered antibodies. The results indicated alleviated...
Background: Diabetes mellitus (DM) is a common chronic endocrine and metabolic disease, its complications can involve multiple organs seriously threaten human health. Double-stranded DNA (dsDNA) plays an important role in the autoimmune system; however, correlation between dsDNA DM has not been fully studied. Methods: This study recruited 388 diabetic patients 2970 healthy controls to investigate relationship serum DM. The diagnosis of was based on medical diagnostic treatment standards for...
Abstract Skin fibrosis, which is characterized by fibroblast proliferation and increased extracellular matrix, has no effective treatment. An increasing number of studies have shown that microRNAs (miRNAs/miRs) participate in the mechanism skin such as limited cutaneous systemic sclerosis pathological scarring. The objective present study was to determine role miR‐411‐3p bleomycin (BLM)‐induced fibrosis transformation. Using Western blot analysis real‐time quantitative polymerase chain...