A5100388464- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Liver Disease Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Cancer-related gene regulation
- Urticaria and Related Conditions
- Food Allergy and Anaphylaxis Research
- Ferroptosis and cancer prognosis
- Asthma and respiratory diseases
- Colorectal Cancer Treatments and Studies
- Radiopharmaceutical Chemistry and Applications
- Autoimmune Bullous Skin Diseases
- Cancer, Lipids, and Metabolism
- Liver physiology and pathology
- Cancer Genomics and Diagnostics
- Gastric Cancer Management and Outcomes
- Electrolyte and hormonal disorders
- Lung Cancer Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Skin and Cellular Biology Research
- Renal cell carcinoma treatment
- melanin and skin pigmentation
- Genetic and rare skin diseases.
- Cancer Research and Treatments
- Vascular Tumors and Angiosarcomas
Shuguang Hospital
2025
Shanghai University of Traditional Chinese Medicine
2025
Capital Medical University
2014-2025
Beijing Children’s Hospital
2017-2025
University of Houston
2023-2025
Juntendo University
2025
Hong Kong Polytechnic University
2024
Beijing Friendship Hospital
2017-2024
Jiangnan University
2024
Wuxi Fourth People's Hospital
2024
Glioblastoma is acknowledged as the most aggressive cerebral tumor in adults. However, efficacy of current standard therapy seriously undermined by drug resistance and suppressive immune microenvironment. Ferroptosis a recently discovered form iron-dependent cell death that may have excellent prospect chemosensitizer. The utilization ferropotosis inducer Erastin could significantly mediate chemotherapy sensitization Temozolomide exert anti-tumor effects glioblastoma. In this study,...
Abstract Objective Angiographic slow/no‐reflow during emergency percutaneous coronary intervention (PCI) in patients with ST‐elevated acute myocardial infarction (AMI) may result unfavorable outcomes. The aim of our study was to investigate the clinical factors and angiographic findings that predict phenomenon long‐term prognosis AMI slow/no‐reflow. Methods A total 210 consecutive patients, who underwent primary PCI within 12 hours symptom onset were divided into a normal flow group...
Neurological manifestations are potentially associated with hepatitis E virus (HEV) infection in Europe, mainly attributed to genotype (GT) 3 HEV infection. In this study, we determined the frequency and causal relationship of patients non-traumatic neurological disorders China, where GT4 is prevalent. 1117 consecutive diagnosed illnesses a hospital eastern China 1475 healthy controls who took routine examination same were tested for by serology molecular methods. Anti-HEV IgM antibodies...
To compare the performance of radiomics to that Prostate Imaging Reporting and Data System (PI-RADS) v2.1 scoring system in detection clinically significant prostate cancer (csPCa) based on biparametric magnetic resonance imaging (bpMRI) vs. multiparametric MRI (mpMRI).A total 204 patients with pathological results were enrolled between January 2018 December 2019, 142 training cohort 62 testing cohort. The model was compared PI-RADS for diagnosis csPCa bpMRI mpMRI by using receiver operating...
Metastatic cancers arise from a decades-long succession of increasingly virulent precursor lesions, each which represents prospective targets for therapeutic intervention. This evolutionary process has been particularly vivid in esophageal adenocarcinoma (EAC), as this cancer and associated including Barrett's esophagus (BE), low-grade dysplasia (LGD), high-grade (HGD), co-exist an accessible, two-dimensional pattern mucosa. Given the durability these it is likely that they, like EAC, rely...
Abstract Aims The effect of changes in serum sodium levels on the survival patients with heart failure (HF) is unclear. We aimed to analyse impact level trajectories intensive care unit (ICU) HF. Methods A total 4760 diagnosed HF between 2001 and 2012 from Medical Information Mart for Intensive Care III (MIMIC‐III) database were extracted. Of these patients, 1132 who died within 48 h ICU admission excluded, 3628 included this retrospective cohort study. Sodium measured at baseline, 6, 12,...
Objectives This case demonstrates the efficacy and safety of Traditional Chinese Medicine manual therapy (TCMMT) for treatment mild to moderate AIS. Methods An 10-year-old girl who suffered from low back pain (LBP) with marked shoulder inequality razorback postural abnormalities, a clinical diagnosis idiopathic scoliosis, Cobb angle 20° trunk rotation (ATR) thoracic vertebral segment at 7°, ATR lumbar 8°, was treated TCMMT. The patient initially recovered centralized LBP repeated TCMMT twice...
Wound infection and poor wound healing are the major challenges of treatment. Antibiotic drug treatment is effective way to inhibit infection. It necessary achieve sustained release antibiotics get a longer for The double network hydrogels based on liposome, polyethylene glycol (PEG), α- cyclodextrin ( α-CD) acrylamide (AM) were developed, in which liposome acts as amoxicillin repository. Because would from multiple barriers including two cavities α-CD, well - cyclodextrin/acrylamide...
Background: Atopic dermatitis (AD) is a common cutaneous disease in childhood, associated with imbalances the skin microbiota. Objective: To explore characteristics of microbiota and its dynamic changes during clinical treatment AD patients. Methods Cutaneous swab samples were collected from 51 patients for 16S rDNA analysis before treatment, 40 remained sample collection after two-week mometasone mupirocin. In parallel, 31 healthy children (HC) each enrolled to collect single sample....
Background:The increase in lung cancer screening is intensifying the need for a noninvasive test to characterize many indeterminate pulmonary nodules (IPN) discovered.Correctly identifying non-cancerous needed reduce overdiagnosis and overtreatment.Alternatively, early identification of malignant may represent potentially curable form cancer.Objective: To develop validate plasma-based multiplexed protein assay classifying IPN by discriminating between those with diagnosis established...
Background: Parotid and submandibular glands have different properties including characteristics of the secreted saliva tumor incidences. The differences in parotid are not clear from a genetic viewpoint. Objective: To study differential gene expression profiles between normal human glands. Materials methods: Three pairs were obtained. RNA was extracted these samples. After reverse transcription, cDNA vitro ‐transcribed to produce biotin‐labeled cRNA. purified cRNA samples hybridized...
In order to investigate the effect of daily emollient treatment on infantile atopic dermatitis (AD) during maintenance period, a total 309 children younger than 2 years with moderate AD (155 and 154 in control groups, respectively) were enrolled this multicenter, randomized, parallel controlled clinical trial. Subjects topically treated desonide cream emollients Prinsepia utilis Royle for 2-4 weeks before entering period then differentially either or none control. The cumulative rate, time...
Abstract Skin fibrosis, which is characterized by fibroblast proliferation and increased extracellular matrix, has no effective treatment. An increasing number of studies have shown that microRNAs (miRNAs/miRs) participate in the mechanism skin such as limited cutaneous systemic sclerosis pathological scarring. The objective present study was to determine role miR‐411‐3p bleomycin (BLM)‐induced fibrosis transformation. Using Western blot analysis real‐time quantitative polymerase chain...
Urticarial vasculitis (UV) is a small vessel leucocytoclastic vasculitis, which often needs to be distinguished from urticaria and other dermatoses. Treatment of UV in children challenging because the unsatisfying efficacy antihistamines safety concern long-term systemic corticosteroids or immunosuppressive agents. As classic biological agent widely used chronic spontaneous urticaria, omalizumab might also potential therapeutic option treatment with UV. This report presented four children,...
Scavenger receptor class B type I (SRBI) promotes cell cholesterol efflux and the clearance of plasma cholesterol. Thus,