Farhad Abolnezhadian
A5003410541- Immunodeficiency and Autoimmune Disorders
- Blood disorders and treatments
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Immune responses and vaccinations
- Immune Cell Function and Interaction
- Blood Pressure and Hypertension Studies
- Nutritional Studies and Diet
- T-cell and B-cell Immunology
- Pneumocystis jirovecii pneumonia detection and treatment
- Asthma and respiratory diseases
- Health Promotion and Cardiovascular Prevention
- Pediatric health and respiratory diseases
- Liver Disease Diagnosis and Treatment
- Congenital Ear and Nasal Anomalies
- Congenital Diaphragmatic Hernia Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Parvovirus B19 Infection Studies
- Global Public Health Policies and Epidemiology
- Diet, Metabolism, and Disease
- Vitamin C and Antioxidants Research
- Health Systems, Economic Evaluations, Quality of Life
- Consumer Attitudes and Food Labeling
- Diabetes Management and Education
- Allergic Rhinitis and Sensitization
Ahvaz Jundishapur University of Medical Sciences
2016-2024
Islamic Azad University, Shoushtar Branch
2020-2023
Tehran University of Medical Sciences
2017
Namazi Hospital
2014-2015
Shiraz University of Medical Sciences
2015
Abstract Although it is estimated that COVID-19 life-threatening conditions may be diagnosed in less than 1:1000 infected individuals below the age of 50, but real impact this pandemic on pediatric patients with different types primary immunodeficiency (PID) not elucidated. The current prospective study a national registry PID showed only 1.23 folds higher incidence infections, these present 10-folds mortality rate compared to population mainly combined and immune dysregulation. Therefore,...
Inborn errors of immunity (IEIs) are a heterogeneous group genetic defects immunity, which cause high rates morbidity and mortality mainly among children due to infectious non-infectious complications. The IEI burden has been critically underestimated in countries from middle- low-income regions the majority patients with these lack molecular diagnosis.We analyzed clinical, immunologic, data 22 Middle East North Africa (MENA) region. was collected national registries diverse databases such...
Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the infection leads to hypoxemic pneumonia, although it is much more rare in children.
Asthma is a heterogeneous disease which usually associated with chronic airway inflammation. Saffron has anti-inflammatory effects and may beneficial on asthma. The present study was intended to survey the of saffron supplementation blood pressure, lipid profiles, basophils, eosinophils clinical symptoms in patients allergic Our trial. Subjects (N = 80, 32 women 48 men, 41.25 ± 9.87 years old) mild moderate asthma were randomized into two groups: intervention group who received capsules (100...
Background: The role of metabolic states in cardiovascular risks among individuals with varying degrees obesity is unknown. study aimed to compare cardiometabolic index (CMI), atherogenic plasma (AIP), lipid accumulation product (LAP) and novel anthropometric indices non-metabolically obese individual regard the FTO gene Iranian adults. Methods: In total, 165 were recruited into this cross-sectional study. Individuals grouped four groups: healthy normal-weight (MHNW) individuals,...
Despite all recent health-related improvements, anemia remains an extensive global public health issue affecting the lives of about one-fourth world population in a geographically heterogeneous pattern. We, therefore, aimed to illustrate prevalence, severity, most common types, and major determinants among adults Khuzestan, Iran, from 2016 2019.
Abstract Allergic diseases are prevalent chronic conditions among children and can lead to significant health economic issues. It is hypothesized that healthy high quality diet during pregnancy prevent the onset of allergic in offspring. This study aimed investigate potential relationship between major dietary patterns allergies under one year age. case–control was conducted involving 244 participants (122 mothers 122 controls) who visited pediatricians allergy outpatient clinics Khuzestan...
Background: Asthma essentially represents a chronic inflammatory disease that manifests as lifelong condition with different severity throughout the life of patients asthma. Pomegranate holds three times antioxidant activity compared to other polyphenol-rich food sources like green tea, which may positively impact Aim study: This research aimed investigate pomegranate supplementation influences clinical symptoms, eosinophil, basophil, and neutrophil counts in allergic Materials Methods:...
BackgroundSevere acute respiratory syndrome coronavirus 2 was first reported in December 2019 and it has spread globally ever since. The HLA system is crucial directing anti-viral immunity recent studies are investigating the possible involvement of genes on severity immune inflammation different phases COVID-19.MethodsIn this cross-sectional study, peripheral blood-extracted genomic DNAs 109 COVID-19 patients 70 healthy controls were genotyped for alleles HLA-A, HLA-B, HLA-DRB1 loci using...
Severe combined immunodeficiency (SCID) is a life-threatening pediatric disease. We report on the clinical evaluation, immunological assessment, molecular analysis, and outcomes of SCID patients in tertiary referral center Iran.From January 2006 to December 2015, we performed prospective cohort study which initial screening advanced tests were carried out suspected having SCID. Genetic analysis was also confirm diagnosis.A total 63 diagnosed with (43 male [68.3%]). The median age at onset...
Primary immunodeficiency (PID) is a group of more than 400 distinct genetic disorders affecting both children and adults. As signs symptoms PID are usually heterogeneous unspecific, based on the available human resources laboratory facilities, diagnosis follow-up these patients can be challenging. In line with this notion, management treatment practiced divergently in different centers. order to reach national protocol given little evidence appropriate or universal guidelines improve current...
The Middle East and North Africa (MENA) is postulated to have the highest increase in prevalence of diabetes by 2030; however, studies on epidemiology are rather limited across region, including Iran.This study was conducted between 2016 2018 among Iranian adults aged 20 65 years residing Khuzestan province, southwestern Iran. Diabetes defined as fasting blood glucose (FBG) level 126 mg/dl or higher, and/or taking antidiabetic medications, self-declared diabetes. Prediabetes FBG 100 125...
The dietary approaches to stop hypertension (DASH) encourages high fruit, vegetable, and lean protein consumption low salt, red meat, fat intake prevent or treat hypertension. However, besides hypertension, adherence this diet has been shown decrease other cardiovascular risk factors.This study assessed the relationship between DASH factors in a cross-sectional of 2,831 adults chosen by multistage cluster sampling from 27 counties Khuzestan province, Iran. scores were calculated using data...
Abstract Background Pharmaceutical medications are considered an important component of healthcare delivery and there is a need for its rational use; although have been major improvements in the pharmaceutical sector recent past, inappropriate medication use threat to patients' health. Therefore, pattern should be monitored routinely. The aim this study was investigate population‐based prevalence polypharmacy patterns southwestern Iran. We also investigated correlates between use. Methods...
Abstract Background Chronic kidney disease (CKD) is a growing global health problem with faster progression in developing countries such as Iran. Here we aimed to evaluate the prevalence and determinants of CKD stage III+. Methods This research part Khuzestan Comprehensive Health Study (KCHS), large observational population-based cross-sectional study which 30,041 participants aged 20 65 were enrolled. was determined estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73m 2 ,...
Genetic defects in the development, maturation, and/or function of immune cells can lead to Inborn errors immunity (IEI) which may predispose patients malignancies. The overall risk for cancer children with IEI ranges from 4 25% and type malignancy is highly dependent on specific mutant gene underlying IEI. We investigated 3056 registered Iranian national registry between years 1999 2020 this retrospective cohort study. frequency its association these were evaluated. A total 82 enrolled...
Major histocompatibility complex (MHC) class II deficiency is a rare primary immunodeficiency disorder (PID) with less than 200 cases worldwide. Here, we report an 8 month–old girl MHC novel homozygous mutation in RFXANK gene (NM_001278728: exon 5: c.495G>A: p.Trp165*) and normal CD4+ T cell counts, diagnosed by whole exome sequencing (WES) negative HLA–DR proteins on peripheral blood mononuclear (PBMC) flow cytometry. She was referred pneumonia, prolonged fever, resistance to antibiotics...