- Pancreatic and Hepatic Oncology Research
- Blood Pressure and Hypertension Studies
- Global Health Care Issues
- Healthcare Systems and Reforms
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Global Public Health Policies and Epidemiology
- Head and Neck Cancer Studies
- Health Promotion and Cardiovascular Prevention
- Obesity, Physical Activity, Diet
- Cancer Risks and Factors
- Cancer, Lipids, and Metabolism
- Colorectal Cancer Screening and Detection
- Chronic Disease Management Strategies
- Helicobacter pylori-related gastroenterology studies
- Hepatitis C virus research
- Global Cancer Incidence and Screening
- Health and Well-being Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pregnancy and preeclampsia studies
- Diabetes Management and Education
- Hepatitis B Virus Studies
- Air Quality and Health Impacts
- BRCA gene mutations in cancer
Tehran University of Medical Sciences
2017-2025
Urmia University
2025
Urmia University of Medical Sciences
2025
Shariati Hospital
2018-2024
Institute for Health Metrics and Evaluation
2023
University of Washington
2023
Kiel Institute for the World Economy
2023
University of Electronic Science and Technology of China
2023
Delhi Technological University
2022
Digestive Disease Research Institute
2020
Breast cancer (BC) is one of the most burdensome cancers worldwide. Despite advancements in diagnostic and treatment modalities, developing countries are still dealing with increasing burdens existing disparities. This study provides estimates BC burden associated risk factors Iran at national subnational levels over 30 years (1990-2019).Data on for were retrieved from Global Burden Disease (GBD) 1990 to 2019. GBD estimation methods applied explore incidence, prevalence, deaths,...
Abstract Background Dietary patterns, encompassing an overall view of individuals’ dietary intake, are suggested as a suitable means assessing nutrition’s role in chronic disease development. The aim this study was to evaluate the validity and reproducibility food frequency questionnaire (FFQ) designed for use Prospective Epidemiological Research Studies IrAN (PERSIAN), by comparing major patterns assessed FFQ with reference method. Methods Study participants included men women who enrolled...
Background Lung cancer remains a pressing health issue globally. This study investigates survival rates and the impact of pre-diagnostic factors on lung incidence in Golestan Cohort Study (GCS). Method The GCS, initiated 2004 with enrollment concluding 2008, comprises 49,783 individuals aged 40–75 from province northeastern Iran. Our analysis included all cases lung, tracheal, bronchial cancers diagnosed under ICD-10 codes C33-C34 study’s inception to 2022, tracking participants until death....
This study investigated the survival rates of colorectal cancer (CRC) and association between several pre-diagnostic factors, including demographic, anthropometric, behavioral, nutritional, lifestyle, medical history CRC incidence survival. Among 50,045 participants in Golestan cohort study, 190 patients diagnosed with during follow-up period were included this study. Cox regression Kaplan-Meier used for analysis. The risk was significantly higher males (HR = 2.20; 1.54-3.14), adults aged...
Background: While celiac disease (CD) ordinarily presents with gastrointestinal manifestations, extraintestinal appearances may also happen. Although cutaneous manifestations are one of the most common CD, little is known about their prevalence and associated factors. This study aims to determine related factors in CD patients. Methods: cross-sectional enrolled patients referred National Celiac Registry, for whom a diagnosis was confirmed through clinical examination, serological testing,...
The dietary approaches to stop hypertension (DASH) encourages high fruit, vegetable, and lean protein consumption low salt, red meat, fat intake prevent or treat hypertension. However, besides hypertension, adherence this diet has been shown decrease other cardiovascular risk factors.This study assessed the relationship between DASH factors in a cross-sectional of 2,831 adults chosen by multistage cluster sampling from 27 counties Khuzestan province, Iran. scores were calculated using data...
The Middle East and North Africa (MENA) is postulated to have the highest increase in prevalence of diabetes by 2030; however, studies on epidemiology are rather limited across region, including Iran.This study was conducted between 2016 2018 among Iranian adults aged 20 65 years residing Khuzestan province, southwestern Iran. Diabetes defined as fasting blood glucose (FBG) level 126 mg/dl or higher, and/or taking antidiabetic medications, self-declared diabetes. Prediabetes FBG 100 125...
BACKGROUND Aryl-carbon receptor (AhR), a ligand-activated transcription factor, is best known for its ability to mediate the effects of environmental toxins such as 2,3,7,8-tetrachlorodibenzo-p-dioxin. AhR expressed in several tumor cells and regulates expression genes signal transduction pathways. In this study, we examined soluble levels patients with pancreatic cancer. METHODS 123 samples, including 59 (48%) samples ductal adenocarcinoma based on histological evidence 64 (52%) healthy...
Abstract Background As pancreatic cancer (PC) is a malignancy with poor prognosis, finding strategies for its prevention became notable priority. Among all the factors influencing risk of PC, dietary items especially fats are considered as most modifiable factors.This study designed to assess associations intake fatty acids PC incidence. Methods A total 50,045 adults between 40 and 75 years old participated in this cohort 2004–2008 were followed up present. Intakes was evaluated by validated...
Objectives Investigating the survival features, and determinants of treatment stage at presentation in Iran Methods 461 patients with pancreatic ductal adenocarcinoma (PC) were prospectively enrolled from Shariati hospital, Tehran, Iran, between 2011–2018. All underwent endoscopic ultrasonography, computed tomography scanning, physical examination. Validated questionnaire was completed for participants all actively followed on monthly basis. Results Median time 6.5 months, 1-, 5-year rates...
Non-communicable diseases (NCDs) are the leading cause of death worldwide, with a disproportionally rising burden among low- and middle-income populations. While preventable risk factors highly contribute to this burden, population-based studies assessing these health status populations, scarce.The Khuzestan Comprehensive Health Study (KCHS)-a cross sectional study-was conducted between 2016-2019, including 30,506 Iranians aged 20 65 years, from 27 counties province, southwest Iran. KCHS...
BACKGROUND Pancreatic cancer (PC) is a deadly disease with 5-year survival of less than 5%. Worldwide PC incidence rates are lower among women men. While this suggests protective role for steroid hormones in risk, results from epidemiological studies not consistent. METHODS 153 new incident cases and 202 controls were recruited prospective case-control study, running referral center endoscopic ultrasonography during 2011-2017. A structured valid reliable questionnaire was used data...
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate approximately 5%. The incidence and mortality rates PDAC are increasing, results medical treatments remain unsatisfactory. Some conflicting evidence suggests that aspirin intake may reduce risk PDAC. This study aimed to evaluate association between regular low-dose use (80-mg tablets, 5-7 tablets/week) Methods: prospective, hospital-based, case-control was performed on 470...
Cardiovascular diseases (CVDs) are the leading causes of global mortality and disability. Several studies demonstrated that metabolic risk factors increase cardiovascular mortality. The aim this study is to examine CVDs deaths population attributable fractions (PAFs) their in Iran.
Background Environmental risk factors are significant contributors to cancer mortality, which neglected. Purpose This study aimed estimate the population attributable fraction of mortality due environmental factors. Methods Golestan cohort is a population-base on 50045 participants between 40–75 with about 18 years follow up. We detected 2,196 and applied multiple Cox model compute hazard ratio factor all cancer-specific mortality. The was calculated, accordingly. Results Biomass fuels for...
Less is known whether the amino acid composition of dietary protein sources effects on long-term health outcomes. We aimed to evaluate association between and all-cause cause-specific mortality.
<title>Abstract</title> To date, no comprehensive study has been conducted to assess the prevalence of kidney diseases in Iran. With establishment Prospective Epidemiological Research Studies IrAN (the PERSIAN cohort) across various provinces, we aim address this gap using data from baseline phase cohort study. In large-scale population-based cross-sectional study, included 151,227 adult participants (aged 35–70 years) 17 centers The variation CKD was investigated complex survey design....
Abstract Background Chronic kidney disease (CKD) is a growing global health problem with faster progression in developing countries such as Iran. Here we aimed to evaluate the prevalence and determinants of CKD stage III+. Methods This research part Khuzestan Comprehensive Health Study (KCHS), large observational population-based cross-sectional study which 30,041 participants aged 20 65 were enrolled. was determined estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73m 2 ,...
Abstract Aims Cardiovascular diseases (CVDs) are the leading cause of death in world. Many modifiable risk factors have been reported to synergistically act development CVDs. We aimed compare predictive power anthropometric indices, as well provide best cut-off point for these indicators a large population Iranian people prediction CVDs and CVD factors. Methods results All data used present study were obtained from Khuzestan comprehensive health (KCHS). Anthropometric including BMI (body...
BACKGROUND : Pancreatic cancer (PC) is a deadly, globally increasing cancer. The causes of PC are still insufficiently known, however smoking, diabetes mellitus (DM), and obesity have been identified as risk factors PC, mostly in the developed countries. We evaluated these their contribution to among an Iranian population. METHODS: Cases controls were selected from patients who registered tertiary gastrointestinal diseases referral hospital Tehran, Iran, Jan 2012 2018. Information on was...