We have proposed a method for fixing an autolimbal graft using two-component autofibrin glue. The use of this adhesive composition is justified by the formation strong adhesion and tissues fixation, as well relief local inflammatory reaction due to platelet-rich plasma (PRP) included in its composition. Objective . To compare effectiveness transplantation glue suture fixation multiple recurring pterygium over two-year follow-up period. Patients methods study 19 patients (20 eyes) with...

Purpose. Analysis of effectiveness surgery treatment primary and recurrent pterygium using a two-component autofibrin glue in comparison with suture fixation amniotic membrane. Material methods. A comparative analysis the surgical results was done between groups patients (21 eyes) (14 sutures for fixing We evaluated time spent on surgery, postoperative period duration full epithelialization time. Each patient underwent biomicroscopy optical coherence tomography anterior segment. Before...

Diseases and damages of the ocular surface are one common causes decreased vision blindness. Dysfunction or death limbal epithelial stem cells (LESC) plays an important role in development pathological processes these conditions, which leads to cell deficiency (LSCD). Currently, methods treat LSCD is a transplantation cultured ex vivo LESC. The most carriers for cultivation LESC world amniotic membrane (AM). However, presence certain disadvantages using AM compels search new types made from...

BACKGROUND: In recent years, autologous serum has been increasingly used in the treatment of macular hole. The study carried out a biological analysis obtained by various methods.
 AIM: aim investigation is to compare cellular and biochemical composition using different methods for use hole treatment.
 MATERIALS AND METHODS: number platelets, leukocytes fibrinogen level blood 24 patients centrifugation original systems harvesting laboratory test tubes was performed.
 RESULTS:...

To analyze the anatomical and functional outcomes in inferior recurrences of rhegmatogenous retinal detachment (RRD) depending on surgical approach.Eighty-one eyes 81 patients (47 males 34 females with a mean age 54.8±14.1y) who demonstrated at least one recurrence RRD were included this retrospective study. All categorized as having received either circular scleral buckling (SB), pars plana vitrectomy (PPV), combination SB PPV (SB+PPV), retinotomy (PPV+RT), or PPV+RT short-term...

The review is focused on the modern view of etiology and pathogenesis limbal stem cells deficiency. history development tissue ex-vivo transplantation epithelial presented. Certain promising directions treatment patients with deficiency are

Purpose. To describe our technique, clear corneal phacovitrectomy with posterior capsulorhexis (CCPV), for the management of selected segment intraocular foreign body (IOFB), posteriorly dislocated lens fragments (PDLF), and proliferative diabetic retinopathy (PDR) cases. Methods. This was a single-center retrospective interventional case series. In 21 patients (21 eyes) we performed through three tunnel incisions (CCTI) to remove IOFB (n = 8), PDLF from vitreous cavity after complicated...

Purpose: to provide clinical and morphological evaluation of the corneal epithelium phenotype in total vascular leukomas varied etiologies determine optimal surgical treatment using impression cytology (IC). Materials methods. 44 patients (44 eyes) with various underwent optic keratoplasty preceded by IС. The were divided into 2 groups according IC findings. Group 1 included 30 who shown have epithelium. These received penetrating (PK). consisted 14 whose was determined be conjunctival...

Keratoconus is a bilateral, progressive corneal disease affecting all ethnic groups around the world. It one of major ocular problems with significant social impacts as affects young generation, and leading cause transplantation. Although keratoconus associated genetic environmental factors, its precise etiology not yet established. Results from complex segregation analysis patterns gene expression show that abnormalities may play an essential role in susceptibility to keratoconus. There...

Introduction. Ocular surface diseases related with limbal epithelial stem cells dysfunction were united in term “limbal cell deficiency” (LSCD). For experimental study of the regenerative processes and evaluation success new LSCD treating methods model is required. Various models proposed experiment to study: mechanical, thermal, chemical, medicamental. The main lack these relative high cost complexity execution. mechanical allows for guaranteed removal tissues containing LESCs, therefore...

Introduction . In a number of pathological conditions accompanied by the basement membrane defects, such as chemical or thermal burns, mechanical trauma, Sjögren’s syndrome, neurotrophic keratopathy some corneal dystrophies, in which are created independent epithelialization is weakened becomes impossible. This condition was named recurrent erosion (RCE). For experimental study regenerative processes and evaluation effectiveness new treatments, standardized reproducible RCE model needed....

Purpose : to evaluate the features and outcomes of penetrating keratoplasty in combined opto-reconstructive surgery for combat eye injury its complications. Patients methods . The study enrolled 17 eyes (16 men) aged 34.00 ± 12.51 years, divided into 2 groups: I — with inflammatory diseases anterior segment, complicated (4 eyes), II open (OGI, 13 eyes). underwent examination reveal localize damaged intraocular structures foreign bodies (IOFB), determine prognosis visual functions, as well...

There are many ways of surgical treatment pterygium, including combined methods. Despite a wide range technics, their effectiveness remains an actual problem because high recurrence rates. Autolimbal transplantation as pathogenetically oriented way treating partial limbal deficiency, which results in minimizes its growth. Due to the trend towards use adhesive compositions for tissue fixation, we have proposed fixation autolimbal graft using two-component autofibrin glue. A comparative...

Актуальность. Частота боевой травмы глаза достигает в вооруженных конфликтах последних десятилетий 10–13 %. Увеличивается доля сочетанных, множественных и комбинированных поражений, а также процент инфекционных осложнений. ПВР — самое грозное из них. Цель. Оценить результаты многоэтапного лечения посттравматической ПВР, осложняющей БОТГ с повреждением структур переднего заднего сегментов. Материал методы. I группа ОТГ сегментов 23 пациента (25 глаз), лечение клинике офтальмологии ВМедА...

Актуальность.В лечении лимбальной недостаточности различной этиологии важную роль играют обогащенная тромбоцитами плазма и разработанный на кафедре офтальмологии им. проф. В.В. Волкова ВМедА двухкомпонентный аутофибриновый клей (ДАФК) ее основе. Цель.Оценить результаты применения ДАФК в хирургии глазной поверхности при недостаточности. Материал методы. применяли эрозий язв роговицы, болезни кератотрансплантата с персистирующими эрозиями, рецидивирующем птеригиуме реабилитации пациентов...

Актуальность. Проблема лечения персистирующих эрозий роговицы (ПЭР) представляет собой значимую задачу для современной офтальмологии. Местное применение раствора инсулина в качестве дополнительной терапии может значительно улучшить эффективность стандартных методов лечения. Цель. Исследовать местного применения ПЭР сравнении со стандартным лечением. Материал и методы. Исследование проводилось на 9 кроликах (18 глаз), которых была создана модель ПЭР. Глаза были разделены контрольную (9 глаз)...

Purpose. to compare the traditional suture and combined methods of amniotic membrane (AM) fixation during surgical treatment persistent corneal erosion (PER). Material methods. The study was carried out on 50 patients (54 eyes). All eyes were divided into 2 groups: experimental (combined method AM using sutures two-component autofibrin glue (DAPK)) control (fixation with sutures). A comparative assessment out: period lysis, area epithelium defects before after surgery, presence/absence OCT...

Purpose. To evaluate the efficacy of phototherapeutic keratectomy (PTK) in treatment persistent and recurrent keratograft erosions after penetrating keratoplasty. Material methods. A series 6 clinical cases patients with or epithelial defects keratoplasty that were not treatable by conservative methods is presented. All underwent keratectomy. Results discussion. In all cases, full epithelialization was achieved 3.7 ± 0.8 days. According to LogMAR scale, visual acuity 1.79 0.24 before...

Purpose. To evaluate the results of penetrating keratoplasty (PK) as an element opto-reconstructive surgery (ORS) for combat injury to eye. Material and method. The study included 43 eyes 39 male patients aged 22 59 years. were divided into two groups: main group — OGI with damage structures anterior posterior segments 34 (37 eyes), control inflammatory diseases segment that complicated severe eye intact 5 (6 eyes). All underwent PK, in addition which there could be: installation a temporary...

The share of eye injuries in Russia is from 3 to 8% the total number peacetime. Eye trauma one three main causes vision disability and accounts for 22.8%. In wartime, mass admission wounded with damage organ requires prompt decisions on their sorting, treatment, rehabilitation, dismissal, or return duty. peacetime, mechanical associated working population large material costs. Considering relevance eye, ophthalmologists around world are constantly investigating features pathogenetic...

Currently, the system of Ministry Health Russia has adopted classification eye burns, proposed in 1973 by N.A.Puchkovskaya and V.M.Nepomashy. The appearance recent years concept limbal stem cells corneal epithelium its application clinical practice significantly expanded possibilities diagnostics, treatment, visual rehabilitation patients with burns. In 1997, M.D.Wagoner a which gradation burn severity is determined degree damage to cells. Taking into account this modern approach, new burns proposed.

Purpose: To assess the iridocrystalline complex status in patients with cataract, complicated by zonular weakness, before and after surgical treatment. Patients Methods. The study enrolled 28 (29 eyes) weakness (8 women, 20 men, 74.13 ± 8.48 years old). All undergone phacoemulsification IOL implantation a capsular tension ring (CTR) if it was necessary. In each case optical biometry, ultrasound biomicroscopy applanation tonometry were provided. After 1, 3 6 months postoperatively...

Complicated myopia (CM) is not only a refractive error but complex, multifactorial disorder characterized by mismatch between the optical power of eye and axial length that causes image to be focused off retina. Genetic factors in progressive play key role determining impact ecologic on refraction development. The majority genetic variants underlying CM are modest effect and/or low frequency, which makes them difficult identify using classic approaches. genes identified date account for less...