A5037254388- Malaria Research and Control
- Mosquito-borne diseases and control
- Global Maternal and Child Health
- COVID-19 epidemiological studies
- Healthcare Systems and Reforms
- Child Nutrition and Water Access
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Computational Drug Discovery Methods
- Diverse Scientific Research Studies
- Epilepsy research and treatment
- Tuberculosis Research and Epidemiology
MalariaGEN
2021-2024
Ministère De La Santé
2019
Abstract Background The World Health Organization recommends regularly assessing the efficacy of artemisinin-based combination therapy (ACT), which is a critical tool in fight against malaria. This study evaluated two combinations recommended to treat uncomplicated Plasmodium falciparum malaria Burkina Faso three sites: Niangoloko, Nanoro, and Gourcy. Methods was two-arm randomized control trial artemether-lumefantrine (AL) dihydroartemisinin-piperaquine (DP). Children aged 6–59 months old...
Background In 2012, the WHO issued a policy recommendation for use of seasonal malaria chemoprevention (SMC) to children 3–59 months in areas highly transmission. Clinical trials have found SMC prevent around 75% clinical malaria. Impact under routine programmatic conditions has been assessed during research studies but there is need identify sustainable methods monitor impact using routinely collected data. Methods Data from Demographic Health Surveys were merged with rainfall, geographical...
Seasonal malaria chemoprevention (SMC) is a WHO-recommended intervention for children aged 3-59 months living in areas of high transmission to provide protection against during the rainy season. Operational guidelines were developed, based on WHO guidance, support countries mitigate risk coronavirus disease 2019 (COVID-19) within communities and among community distributors when delivering SMC.A cross-sectional study determine adherence infection prevention control (IPC) measures two...
Seasonal malaria chemoprevention (SMC) is a World Health Organization-recommended intervention for the prevention of among children at high risk in areas with seasonal transmission. During coronavirus disease 2019 (COVID-19) pandemic, SMC drug distribution was rapidly adapted to reduce contact and mitigate transmission between communities community distributors, caregivers administering doses. To address challenges find local solutions improve administration adherence, role model approach...
Abstract Background Malaria and malnutrition represent major public health concerns worldwide especially in Sub-Sahara Africa. Despite implementation of seasonal malaria chemoprophylaxis (SMC), an intervention aimed at reducing incidence among children aged 3–59 months, the burden associated mortality below age 5 years remains high Burkina Faso. Malnutrition, particular micronutrient deficiency, appears to be one potential factors that can negatively affect effectiveness SMC. Treating...
In rural African settings, most of the children under coverage Seasonal Malaria Chemoprevention (SMC) are also undernourished at time SMC delivery, justifying need for packaging malarial and nutritional interventions. This study aimed assessing impact by coupling intervention with nutrients supplementation preventing malaria in less than 5 years old Burkina Faso.A randomized trial was carried out between July 2020 June 2021 health district Nanoro, Faso. Children (n = 1059) were randomly...
Abstract Background Seasonal Malaria Chemoprevention (SMC) is a highly effective intervention for preventing malaria, particularly in areas with seasonal transmission. Monitoring and evaluating (M&E) SMC programmes are complex due to the scale, time-sensitive delivery of programme, influence external factors. This paper describes process followed develop comprehensive M&E framework tailored specifically context. Methods The Framework was developed through literature programme review,...
<title>Abstract</title> <bold>Background</bold> Seasonal malaria chemoprevention (SMC) is a World Health Organization-recommended intervention for the prevention of among children at high risk in areas with seasonal transmission. During coronavirus disease 2019 (COVID-19) pandemic, SMC drug distribution was rapidly adapted to reduce contact and mitigate transmission between communities community distributors, caregivers administering doses. To address challenges find local solutions improve...
<title>Abstract</title> Background Since 2012, the World Health Organization has recommended seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine (SPAQ) for children aged 3–59 months in areas marked seasonality transmission. Full ingestion of SMC medicines without spitting or vomiting during a complete three-day course is critical to ensure effectiveness and avoid increased antimalarial resistance. Although evidence suggests that not rare, there limited...
Since 2012, the World Health Organization has recommended seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine (SPAQ) for children aged 3-59 months in regions where transmission is seasonal. Full ingestion of SMC medicines without spitting or vomiting during a complete 3-day course critical to ensure effectiveness and avoid development antimalarial resistance. Although evidence suggests that not rare, there limited analytical on potential factors associated...
One of the major contributors malaria-related deaths in Sub-Saharan African countries is limited accessibility to quality care. In these countries, malaria control activities are implemented at health-district level (operational entity national health system), while readiness indicators regionally representative. This study provides an approach for estimating district-level from survey data designed provide representative estimates. A binomial-hierarchical Bayesian spatial prediction method...
Abstract Background Seasonal Malaria Chemoprevention (SMC) is a highly effective intervention for preventing malaria, particularly in areas with seasonal transmission. Monitoring and evaluating (M&E) SMC programmes are complex due to the scale, time-sensitive delivery of programme, influence external factors. Here we present comprehensive M&E framework tailored specifically context. The Framework was developed through literature programme review, stakeholder dialogues across three...
Abstract Background: One of the major causes malaria-related deaths in Sub-Saharan African countries is limited accessibility to quality care. In these countries, malaria control activities are implemented at health district level. However, indicators often regionally representative. This paper provides an approach for estimating district-level readiness from survey data designed provide representative estimates. Methods: A binomial hierarchical Bayesian spatial prediction method was applied...
<title>Abstract</title> IntroductionSeasonal malaria chemoprevention (SMC) is a WHO-recommended intervention for children aged 3-59 months living in areas of high transmission to provide protection against during the rainy season. Operational guidelines were developed, based on WHO guidance, support countries mitigate risk coronavirus disease 2019 (COVID-19) within communities and among community distributors when delivering SMC.MethodsA cross-sectional study determine adherence infection...