Abstract The global tobacco epidemic is still a devastating threat to public health. Toxic reactive oxygen species (ROS) in the cigarette smoke cannot be efficiently eliminated by currently available filters. resultant oxidative stress causes severe lung injury and further diseases. To tackle this challenge, herein, novel copper tannic acid coordination (CuTA) nanozyme reported as highly active thermostable ROS scavenger. CuTA exhibits intrinsic superoxide dismutase‐like activity,...

Responsive assembly of 2D materials is great interest for a range applications. In this work, interfacial functionalized carbon nitride (CN) nanofibers were synthesized by hydrolyzing bulk CN in sodium hydroxide solution. The reversible assemble and disassemble behavior the as-prepared was investigated using CO2 as trigger to form hydrogel network at first. Compared most widespread absorbent such active carbon, graphene previously reported supramolecular gel, proposed not only exhibited...

In virtue of the inherent molecular recognition and programmability, DNA has recently become most promising for high-performance biosensors. The rationally engineered nucleic acid architecture will be very advantageous to hybridization efficiency, specificity, sensitivity. Herein, a robust split-mode photoelectrochemical (PEC) biosensor miRNA-196a was developed based on an entropy-driven tetrahedral (EDTD) amplifier coupled with superparamagnetic nanostructures. tetrahedron structure...

Inspired by natural DNA networks, programmable artificial networks have become an attractive tool for developing high-performance biosensors. However, there is still a lot of room expansion in terms sensitivity, atom economy, and result self-validation current microRNA sensors. In this protocol, miRNA-122 as target model, ultrasensitive fluorescence (FL) photoelectrochemical (PEC) dual-mode biosensing platform developed using entropy-driven circuit (EDC) cascaded self-feedback DNAzyme...

DNAzyme-based cascade networks are effective tools to achieve ultrasensitive detection of low-abundance miRNAs. However, their designs complicated and costly, the operation is time-consuming. Herein, a novel simple noncascade DNAzyme network designed its amplification effect comparable or even better than many cascading ones. It nonenzymatic, isothermal, bicirculating consisting two toehold-mediated strand-displacement reactions localized strategy. Taking microRNA-122 as target model, this...

Chemical structures of two-dimensional (2D) nanosheet can effectively control the properties thus guiding their applications. Herein, we demonstrate that carbon nitride nanosheets (CNNS) with tunable chemical be obtained by exfoliating facile accessible bulk (CN) different polymerization degree. Interestingly, electrochemiluminescence (ECL) as-prepared CNNS were significantly modulated. As a result, unusual changes for in quenching ECL because inner filter effect/electron transfer and...

Organic dyes are typically applied as photosensitizers in photoelectrochemical (PEC) cells but have not been reported polarity-reversal-mode PEC sensors with excellent sensitivity and accuracy. Herein, an elegant robust biosensor for carcinoembryonic antigen (CEA) has designed by photocurrent polarity switching of CdTe quantum dots (QDs), which is obtained embedding methylene blue (MB) into amplified double-stranded DNA (dsDNA) anchored to the superparamagnetic Fe3O4@SiO2. The...

It is critical to develop highly efficient electrocatalysts for water splitting achieve energy-saving hydrogen production. Recently, fullerene-based have been widely reported cathodic evolution reaction (HER), while...

As an emerging semiconductor, graphite-phase polymeric carbon nitride (GPPCN) has drawn much attention not only in photocatalysis but also optical sensors such as electrochemiluminescence (ECL) sensing of metal ions. However, when the concentrations interfering ions are several times higher than that target ion, it is almost impossible to distinguish which ion changes ECL signals real sample detection. Herein, we report dual-ECL could be actuated by different reactions merely from GPPCN...

C60 can accept up to six electrons reversibly and show exceptional light absorption over the entire UV–vis spectrum, making it a potential photoactive probe for photoelectrochemical (PEC) bioassay. However, few successful works have been reported apply fullerenes in PEC biosensing, partially because of low electronic conductivity poor interfacial interactions with targeted biomolecules. Herein, we report addressing these two obstacles by coupling high conductive graphite flake (Gr), graphene...

Due to exceptional electron-accepting ability, light-absorption, and a delocalized conjugated structure, buckminsterfullerene (C60) has attracted fascinating interest in the field of organic solar cells. However, poor delocalization accumulation electrons for pristine C60 physiological aqueous solution difficulties conjugation with biomolecules limit its extended photovoltaic applications bioassay. Herein, we reported noncovalent coupling an electronically complementary porphyrin-derived...

Infrared small target detection (ISTD) has a wide range of applications in both military and civilian fields. Due to their low contrast the absence color texture information, targets infrared images can be readily obscured by complex background clutter. Most existing methods primarily concentrate on local modeling, but they lack sufficient feature interactions, leading loss valuable information. Hence, we propose straightforward efficient cross-layer guided multiscale network (CMNet) for...

The seismic performance of prefabricated segmental bridge columns (PSBCs) with ultrahigh-performance fiber-reinforced concrete (UHPFRC) bottom segments was investigated through model tests and numerical simulations in this study. Four large-scale PSBC specimens different were designed tested under cyclic quasi-static loading. A novel segment construction, combining a RC cast-in-place inner column an UHPFRC external precast hollow column, proposed to improve the energy dissipation capacity...

DNA circuits as one of the dynamic nanostructures can be rationally designed and show amazing geometrical complexity nanoscale accuracy, which are becoming increasingly attractive for entropy-driven amplifier design. Herein, a novel elegant exciton–plasmon interaction (EPI)-based photoelectrochemical (PEC) biosensor was developed with assistance programmable superparamagnetic nanostructures. Low-abundance miRNA-let-7a model efficiently initiate operation amplifier, released output DNAs open...

King (Chinook) salmon is the only species farmed in Aotearoa New Zealand and accounts for over half of world's production king salmon. Determining health status effectively important farming. However, it a challenging task due to complex biotic abiotic factors that influence health. Evolutionary machine learning algorithms have shown their superiority models tasks. they not been investigated prediction This paper focuses on data processing algorithm design develop Zealand. Particularly, this...

Sugarcane smut caused by Sporisorium scitamineum leads to a significant reduction in cane yield and sucrose content. MicroRNAs (miRNAs) play an important role regulating plant responses biotic stress. The present study was the first use two sugarcane genotypes, YA05-179 (smut-resistant) ROC22 (smut-susceptible), identify differentially expressed miRNAs challenged with S. using high-throughput sequencing. predicted target gene number corresponding known less than that ROC22, however most of...

Sleep disturbance is common in patients with cancer and associated poor prognosis. However, the effects of sleep deprivation (SD) on immune surveillance during development hepatocellular carcinoma (HC) underlying mechanisms are not known. This was investigated present study using mouse models SD tumorigenesis. We determined that acute chronic (CSD) altered relative proportions various cell types blood peripheral organs. CSD increased tumor volume weight, an effect enhanced increasing time....