A5048277936- Atherosclerosis and Cardiovascular Diseases
- Systemic Lupus Erythematosus Research
- Peripheral Neuropathies and Disorders
- Autoimmune and Inflammatory Disorders Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Heart Failure Treatment and Management
- Systemic Sclerosis and Related Diseases
- Autoimmune Neurological Disorders and Treatments
- Redox biology and oxidative stress
- Rheumatoid Arthritis Research and Therapies
- Antioxidant Activity and Oxidative Stress
- GDF15 and Related Biomarkers
- Hemodynamic Monitoring and Therapy
- Ultrasound in Clinical Applications
- Estrogen and related hormone effects
- Cardiac and Coronary Surgery Techniques
- Pulmonary Hypertension Research and Treatments
- Otolaryngology and Infectious Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Eosinophilic Disorders and Syndromes
- Nursing Diagnosis and Documentation
- RNA regulation and disease
- Phonocardiography and Auscultation Techniques
- Venous Thromboembolism Diagnosis and Management
- Cell Adhesion Molecules Research
Vilnius University
2009-2024
C-reactive protein is a powerful independent predictor of cardiovascular events in patients with coronary artery disease. The relation between (CRP) concentration and in-hospital outcome, after bypass grafting (CABG), has not yet been established. study aims to evaluate the predictive value pre-operative CRP for CABG surgery. High-sensitivity (hs-CRP) levels were measured pre-operatively on day surgery 66 scheduled elective pump Post-operative such as death from causes, ischemic stroke,...
Glutathione and glutathione S-transferases (GST) are involved in cell defence against reactive oxygen species, which induces oxidative stress associated with different chronic diseases. The aim of the present study was to determine differences reduced (GSH) GST levels patients liver diseases.Overall, 114 were enrolled this study: 58 colorectal cancer (18 without 40 metastases), 27 steatosis, 29 alcoholic cirrhosis a group healthy volunteers. GSH blood serum evaluated by enzyme-linked...
Endothelium forms an inner layer of vascular wall. It plays important role in inflammatory process, regulation tone, and synthesis thromboregulatory substances. Leukocyte endothelium interactions during inflammation are regulated by different families adhesion molecules. Increased levels soluble molecules have been detected the circulating blood conditions such as autoimmune diseases, transplant rejection, ischemia-reperfusion injury addition to neutrophil- endothelial membrane-bound...
This study describes the development of a beverage made from curd whey with addition functional ingredients such as calcium, vitamin D3, prebiotic dietary fiber, and its influence on human health. Samples beverages added calcium phosphate or lactate were analyzed for selection optimal preparation. Quality attributes evaluated in their fresh state during storage at intervals 15, 30, 45 days. The was chosen one most stable quality indices evaluation effect health status volunteers (n=30). Five...
Background and Objectives: Early undifferentiated arthritis (UA) is a group of inflammatory joint diseases that are not classified under any specific rheumatic or connective tissue disorder might evolve into chronic may be self-limiting condition. recognition treatment crucial for the future course disease. Vascular endothelial growth factor (VEGF) an angiogenic regulator induces new capillary blood vessels, which important in invasion destruction during progression arthritis. The aim this...
Detection of neuronal antibodies for autoimmune encephalitis and paraneoplastic neurological syndromes relies on commercially available cell-based assays lineblots. However, lineblots may reveal the presence in patients with various non-autoimmune etiologies. Herein we describe etiologies (cohort B) detectable compare them to definite cases A) differences clinical data. All positive at least one antibody were retrospectively evaluated and/or syndrome between 2016 2022. 39 cohort B 23 A...
Abstract Objectives Endothelin-1 (ET-1) has been implicated in the pathogenesis of inflammatory and fibrotic diseases, including systemic sclerosis. In addition to modulating vascular tone extracellular matrix turnover, ET-1 up-regulates cell surface adhesion molecules–intercellular molecule-1 (ICAM-1) (VCAM-1).The aim study was evaluate diagnostic value detection ET-1, VCAM-1 ICAM-1 diagnosis Methods A total 30 patients with sclerosis from Vilnius University Hospital Santaros Clinics were...
1. Recent progress in the use of functional foods for older adults: A narrative review Anna Jędrusek‐Golińska, Danuta Górecka, Maciej Buchowski, Katarzyna Wieczorowska‐Tobis, Gramza‐Michałowska, Krystyna Szymandera‐Buszka Comprehensive Reviews Food Science and Safety CrossRef
Abstract Aims Readmission and mortality are the most common often combined endpoints in acute heart failure (AHF) trials, but an association between these two outcomes is poorly investigated. The aim of this study was to determine whether unplanned readmission associated with a greater subsequent risk death patients dyspnoea due cardiac non‐cardiac causes. Methods results Derivation cohort (1371 from LEDA study) validation (1986 BASEL V included admitted emergency department. Cox regression...
Abstract Objectives Neuromyelitis optica (NMO) is frequently associated with aquaporin‐4 autoantibodies (AQP4‐Ab); however, studies of NMO in Lithuania are lacking. Therefore, the main objective our study to assess positivity for AQP4‐Ab patients presenting inflammatory demyelinating central nervous system (CNS) diseases other than typical multiple sclerosis (MS) Lithuania. Materials and methods Data were collected from two largest University hospitals During period, there 121 newly...
Motivation. Our previous study showed differences in the atherosclerosis phenotype between Lithuanian and Swedish men that could be influenced by complementary factors, namely oxidation processes and/or oxidative stress. The goal of this was to evaluate mainstream biological pathways inducing maintaining atherosclerotic process analyzing genetic biomarkers particularly inflammatory metabolic where main focus is laid on process.Methods. There were 32 families recruited for clinical as well...
To evaluate the potential of soluble cluster differentiation 146 (sCD146) in detection and grading congestion patients with acute dyspnoea. Subanalysis prospective observational Lithuanian Echocardiography Study Dyspnoea Acute Settings (LEDA) cohort. Two university centres. Adult dyspnoea admitted to emergency department. Congestion was assessed using clinical sonographic parameters. All underwent sCD146 N-terminal pro-B-type natriuretic peptide (NT-proBNP) testing. The median value...
BACKGROUND In this paper we report on the link between increased tryptase levels and prevalence of allergen-specific immunoglobulin E (IgE) in patients with anaphylaxis. The main aim study was to assess corelation elevated anaphylactic reactions, mastocytosis, other types allergic reactions. MATERIAL AND METHODS We enrolled 60 adult patients, aged 18-68 years (mean age 45±8 years). subjects were divided into 3 groups (20 each group) according serum changes: group 1 consisted anaphylaxis...
Background and Objectives: About 40% of early undifferentiated arthritis (UA) progresses to rheumatoid (RA) or other chronic arthritis. Novel diagnostic tools predicting the risk for this progression are needed identify patients who would benefit from aggressive treatment. Evidence on role single-nucleotide polymorphisms (SNPs) in development RA has emerged. The aim our study was investigate association between rs2476601, rs833070, rs6920220 SNPs UA RA. Materials Methods: Ninety-two were...
Abstract Introduction Acute dyspnoea is one of the most common complaints in emergency department with a diverse range diagnoses and vastly different prognosis. There still need for reliable biomarker prognostication acute settings. Purpose To evaluate compare role three biomarkers, which represent pathophysiological pathways, stratifying short-term mortality risk patients admitted to dyspnoea. Methods Prospective observational cohort enrolled 1455 departments two university centres from...