- 3D Printing in Biomedical Research
- Electrochemical sensors and biosensors
- Microfluidic and Capillary Electrophoresis Applications
- Nanofabrication and Lithography Techniques
- Enzyme Catalysis and Immobilization
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced Fluorescence Microscopy Techniques
- Advanced Biosensing Techniques and Applications
- Analytical Chemistry and Sensors
- Hydrogels: synthesis, properties, applications
- Bone Tissue Engineering Materials
- Intestinal and Peritoneal Adhesions
- Cell Image Analysis Techniques
- Innovative Energy Harvesting Technologies
- Chemical Synthesis and Analysis
- Analytical Chemistry and Chromatography
- Click Chemistry and Applications
- Reconstructive Surgery and Microvascular Techniques
- Polymer Surface Interaction Studies
- Hernia repair and management
- Energy Harvesting in Wireless Networks
- Surgical Sutures and Adhesives
- Molecular Junctions and Nanostructures
- Photoacoustic and Ultrasonic Imaging
- Breast Implant and Reconstruction
Seoul National University
2017-2021
Seoul Institute
2019-2020
Government of the Republic of Korea
2020
Chung-Ang University
2014
Yonsei University
2007-2008
Abstract Tissue expansion techniques physically expand swellable gel‐embedded biological specimens to overcome the resolution limit of light microscopy. As benefits come at expense signal concentration, imaging volume and time, mechanical integrity sample, optimal ratio may widely differ depending on experiment. However, existing methods offer only fixed ratios that cannot be easily adjusted balance gain loss associated with expansion. Here, a hydrogel conversion‐based method is presented,...
Expanded polytetrafluoroethylene (ePTFE), also known as Gore-Tex, is widely used an implantable biomaterial in biomedical applications because of its favorable mechanical properties and biochemical inertness. However, infection inflammation are two major complications with ePTFE implantations, pathogenic bacteria can inhabit the microsized pores, without clearance by host immune cells, limited biocompatibility induce foreign body reactions. To minimize these complications, we covalently...
This article presents the efficacy of heat-induced MPC-grafting against excessive fibrous capsule formation and related inflammation in tissues surrounding silicone breast implants inserted a pig model.
Abstract Poly(ethylene glycol)(PEG)‐based interpenetrating polymeric network (IPN) hydrogels were prepared for the application of enzyme immobilization. Poly(acrylamide)(PAAm) was chosen as other IPN hydrogel and different concentration PAAm networks incorporated inside PEG to improve mechanical strength provide functional groups that covalently bind enzyme. Formation confirmed by observing weight per cent gain after incorporation attenuated total reflectance/Fourier transform infrared...
A new energy harvesting technology that extracts from the stray electric field around a three‐wire AC power line is presented. It observed when 20 cm of insulated surrounded with conductive sheet, about mJ harvested in 15 min 1 μF storage capacitor. An autonomous circuit was designed and built adopting an MEMS switch as low leakage, consumption hysteretic switch. demonstrated utilised to drive commercial Zigbee‐based wireless sensor module autonomously. Since it easy safe install, proposed...
In this study, poly(ethylene glycol) (PEG)-based hydrogels having different network structures were synthesized by UV-initiated photopolymerization and used for the enzyme immobilization. PEGs with molecular weight acrylated derivat
Abstract BACKGROUND: The main problem when immobilizing enzyme inside hydrogel is the activity loss of trapped enzymes due to limitation on diffusion. In this study, macroporous poly(ethylene glycol) (PEG) membrane was fabricated using photolithography enhance immobilized enzyme. RESULT: Photopolymerization through designed photomask produced crosslinked with tunnel‐like macropores which were completely opened from top bottom membranes. Arrays pores 50 µm and 100 diameters successfully...
Expansion microscopy (ExM) is a technique in which swellable hydrogel-embedded biological samples are physically expanded to effectively increase imaging resolution. Here, we develop thermoresponsive reversible ExM (T-RevExM), the expansion factor can be thermally adjusted manner. In this method, embedded hydrogels and partially digested allow for swelling of sample–gel hybrid temperature-dependent We first synthesized exhibiting lower critical solution temperature (LCST)- upper (UCST)-phase...
We developed a new method for the de novo formation of fluorophores based on citrate (DNFC) in biological samples. Use an amide coupling reagent and microwave irradiation greatly facilitates fluorophore peptides proteins with N-terminal cysteine or serine. Since serine can form thiazolopyridone- oxazolopyridone-based emitting blue green fluorescence, respectively, by DNFC staining, each organelle, cell tissue exhibited characteristic fluorescence distribution. The staining is able to provide...
In article number 1901673, Yan Lee, Sung-Yon Kim, and co-workers develop ZOOM, a new tissue expansion technique based on the hydrogel conversion reaction, to enable scalable isotropic of biological samples with easily tunable ratio (up eightfold). This method allows for simple flexible wide range samples, from bacteria human brain tissues, super-resolution imaging ordinary microscopes.