A5070455237- Antibiotic Resistance in Bacteria
- Orthopedic Infections and Treatments
- Antibiotic Use and Resistance
- Infective Endocarditis Diagnosis and Management
- Nosocomial Infections in ICU
- Bacterial Identification and Susceptibility Testing
- Fungal Infections and Studies
- Streptococcal Infections and Treatments
- Infectious Aortic and Vascular Conditions
- Healthcare Systems and Practices
- Antifungal resistance and susceptibility
- Infectious Diseases and Tuberculosis
- Diabetic Foot Ulcer Assessment and Management
- Clostridium difficile and Clostridium perfringens research
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- Antimicrobial Resistance in Staphylococcus
- Vibrio bacteria research studies
- Orthopaedic implants and arthroplasty
- Hepatitis C virus research
- COVID-19 Impact on Reproduction
- Long-Term Effects of COVID-19
- Bacterial Infections and Vaccines
- Hematological disorders and diagnostics
- Malaria Research and Control
Centre Hospitalier de Tourcoing
2013-2025
Université de Lille
2024
Centre Val de Loire
2021
Abstract Background Campylobacter spp. bacteremia is a severe infection. A nationwide 5-year retrospective study was conducted to characterize its clinical features and prognostic factors. Methods The included patients with diagnosed in 37 French hospitals participating the surveillance network of National Reference Center for Campylobacters Helicobacters, from 1 January 2015 31 December 2019. goal analyze effects delay appropriate antibiotic therapy other risk factors on 30-day mortality...
Background: The optimal duration of antibiotic treatment for extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) bloodstream infections (BSI) in intensive care unit (ICU) is not established. We aim to evaluate the frequency and clinical outcomesof a short appropriate (≤7 days) (SAT) ESBL-E BSI acquired ICU. specifically assessed rate relapse, in-ICU mortality. Method: All patients who three ICU Northern France between January 2011 June 2022 were included multicenter...
Background: Cefiderocol (CFD) is a novel siderophore cephalosporin developed for the treatment of infections involving multidrug-resistant (MDR) Gram-negative bacilli (GNB) (1–3). For bone and joint (BJIs), use CFD currently neither part its market authorization nor recommended, has not yet been assessed by large-scale studies. Objectives: To fill scarcity data regarding in BJIs, we aimed to describe patients’ infection characteristics along with outcomes infection. Methods: We conducted...
Pseudomonas aeruginosa is a common cause of ventilator-associated pneumonia (VAP). Guidelines recommend dual coverage P. aeruginosa, but the beneficial effect combination therapy controversial. We described antibiotic prescriptions and evaluated clinical impact initial de-escalation strategy in patients with VAP caused by aeruginosa.Between 1994 2014, all 100 our intensive care unit (ICU) were included retrospective cohort study to evaluate prognostic therapy.Eighty-five received 15...
Abstract Background Group B streptococci (S treptococcus agalactiae ) (GBS) is a rare cause of prosthetic joint infection (PJI) occurring in patients with comorbidities and seems to be associated poor outcome. Depiction GBS PJI scarce the literature. Methods A retrospective survey 2 referral centers for bone infections was done Patients history between 2014 2019 were included. descriptive analysis treatment failure done. Risk factors assessed. Results We included 61 patients. Among them, 41...
The optimal length of the intravenous antibiotic treatment periprosthetic joint infections (PJIs) generally ranges from one to six weeks and is a matter debate. Most antibiotics active against Gram-positive cocci (GPC) exhibit both high oral bioavailability bone diffusion. Thus, early therapy may be reasonable option in GPC-related PJIs.A 2 year before after monocentric study that aimed compare two strategies. Empirical postoperative was followed by 7 10 days targeted ('before' group) or...
Abstract Background Staphylococci account for approximately 60% of periprosthetic joint infections (PJIs). Rifampicin (RMP) combination therapy is generally considered to be the treatment choice staphylococcal PJIs but carries an important risk adverse events and drug–drug interactions. Rifabutin (RFB) shares many properties rifampicin causes fewer events. Objectives To compare minimal inhibitory concentration (MIC), minimum bactericidal concentrations (MBC), biofilm eradication (MBEC)...
Community-onset candidemia constitute a distinct clinical entity the incidence of which is increasing. Contribution non-albicans Candida species rising. We describe here first reported case community acquired fungemia due to pulcherrima. Identification level was performed by MALDI-TOF mass spectrometry. Treatment with fluconazole successful. This confirms pathogenic role C. pulcherrima and contribution spectrometry for identification rare species.
The immune reconstitution inflammatory syndrome (IRIS) is a set of clinical and laboratory findings, related to the expression opportunistic infections or cancers. IRIS occurs in two ways: revelation (unmasked disease) deterioration known infection neoplasic disease (paradoxical reaction) [1]. It may be associated with many different pathogens such as Mycobacterium tuberculosis, Cryptococci, JC polyomavirus, hepatitis C B virus [2]. This usually characterized by an increased CD4 cell count...
Cardiobacterium hominis is a member of the HACEK group bacteria, responsible for infective endocarditis, mainly in patients with damaged or prosthetic valves. The low virulence this organism can explain insidious presentation and subacute chronic progression C. endocarditis. Here, 41-year-old man past history surgery Waldhausen type aortic coarctation was hospitalised dyspnea chest pains revealing an acute pulmonary oedema, without fever. Transesophageal echocardiography indicated 20 mm...