A5066058824- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Effects of Exercise
- Cardiovascular Syncope and Autonomic Disorders
- ECG Monitoring and Analysis
- Congenital Heart Disease Studies
- Healthcare Systems and Practices
- Advanced MRI Techniques and Applications
- Muscle activation and electromyography studies
- Cardiac tumors and thrombi
- Phonocardiography and Auscultation Techniques
- Cardiomyopathy and Myosin Studies
- Obstructive Sleep Apnea Research
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Pulmonary Hypertension Research and Treatments
- Takotsubo Cardiomyopathy and Associated Phenomena
- Galectins and Cancer Biology
- Lightning and Electromagnetic Phenomena
- Advanced X-ray and CT Imaging
Michigan Medicine
2010-2025
University of Michigan
2015-2024
University of Pennsylvania
2013
Ann Arbor VA Medical Center
2008-2012
John H. Stroger, Jr. Hospital of Cook County
2005
Rush University Medical Center
2005
Background — The pulmonary veins (PVs) have been demonstrated to often play an important role in generating atrial fibrillation (AF). purpose of this study was determine the safety and efficacy segmental PV isolation patients with paroxysmal or persistent AF. Methods Results In 70 consecutive (mean age, 53±11 years) (58) (12) AF, guided by ostial potentials performed. left superior, inferior, right superior PVs were targeted for all patients, inferior isolated 20 patients. Among 230 PVs, 217...
We conducted a randomized, controlled trial of circumferential pulmonary-vein ablation for the treatment chronic atrial fibrillation.A total 146 patients with mean (+/-SD) age 57+/-9 years who had fibrillation were randomly assigned to receive amiodarone and undergo two cardioversions during first three months alone (the control group) or in combination ablation. Cardiac rhythm was assessed daily telephonic transmissions one year. The left diameter severity symptoms at 12 months.Among 77...
Segmental ostial catheter ablation (SOCA) to isolate the pulmonary veins (PVs) and left atrial (LACA) encircle PVs both may eliminate paroxysmal fibrillation (PAF). The relative efficacy of these 2 techniques has not been directly compared.Of 80 consecutive patients with symptomatic PAF (age, 52+/-10 years), 40 underwent PV isolation by SOCA LACA PVs. During SOCA, potentials recorded a ring were targeted. was performed encircling left- right-sided 1 cm from ostia guided an electroanatomic...
In patients with atrial fibrillation (AF), the risk of thromboembolic events (TEs) is variable and influenced by presence number comorbid conditions. The effect percutaneous left radiofrequency ablation (LARFA) AF on TEs unclear.LARFA was performed in 755 consecutive paroxysmal (n = 490) or chronic 265) AF. Four hundred eleven (56%) had > 1 factor for stroke. All were anticoagulated warfarin 3 months after LARFA. A TE occurred 7 (0.9%) within 2 weeks late 6 to 10 (0.2%), whom still AF,...
Radiofrequency catheter ablation of atrial fibrillation (AF) guided by complex fractionated electrograms has been reported to eliminate AF in a large proportion patients. However, only small number patients with chronic have included previous studies.In 100 (mean age, 57+/-11 years) AF, radiofrequency was performed target at the pulmonary vein ostial and antral areas, various regions left atrium, coronary sinus until terminated or all identified were eliminated. Ablation sites consisted > =...
Abstract In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing most common cardiac arrhythmia. 2007, first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence technological advances have resulted a rapidly changing landscape field ablation, thus stressing need regularly updated versions this partnership which were...
During left atrial (LA) catheter ablation, an atrioesophageal fistula can develop as a result of thermal injury the esophagus during ablation along posterior LA. No in vivo studies have examined relationship to The purpose this study was describe topographic anatomy and LA by use CT.A helical CT scan chest with 3D reconstruction performed 50 patients (mean age, 54+/-11 years) fibrillation before procedure. Consecutive axial sagittal sections were determine relationship, size, thickness...
An anatomic approach of left atrial radiofrequency circumferential ablation (LACA) to encircle the pulmonary veins is often effective in eliminating paroxysmal fibrillation (AF). However, no electrophysiological end points other than voltage abatement and/or conduction slowing or block across lines have been used. It has unclear whether noninducibility AF a clinically useful point.In 100 patients with (mean age, 55+/-10 years), LACA left- and right-sided was performed during AF, additional...
Background— The purpose of this study was to determine the feasibility and mechanistic implications segmental pulmonary vein (PV) ostial ablation during atrial fibrillation (AF). Methods Results— Forty consecutive patients underwent PV isolation for AF. Among 125 PVs targeted isolation, performed AF in 70 veins sinus rhythm 55 veins. A decapolar Lasso catheter positioned near ostium. During AF, electrodes that recorded a tachycardia with cycle length shorter than adjacent left atrium....
Pulmonary Vein Anatomy. Introduction: The anatomic arrangement of pulmonary veins (PVs) is variable. No prior studies have quantitatively analyzed the effects segmental ostial ablation on PVs. aim this study was to determine effect radiofrequency PV anatomy in patients with atrial fibrillation (AF). Methods and Results: Three‐dimensional models PVs were constructed from computed tomographic (CT) scans 58 AF undergoing isolate 10 control subjects without a history AF. CT repeated...
Obesity and obstructive sleep apnea (OSA) are associated with atrial fibrillation (AF). The effects of a large body mass index (BMI) OSA on the results radiofrequency catheter ablation (RFA) AF unclear.To evaluate effect BMI efficacy RFA for AF.RFA was performed in 324 consecutive patients (mean age = 57 +/- 11 years) paroxysmal (234) or chronic (90) AF. diagnosed by polysomnography 32 (10%) prior to ablation. Among patients, 18% had normal (<25 kg/m(2)), 39% were overweight (BMI >/= 25...
Background— Because the genesis of atrial fibrillation (AF) is multifactorial and variable, an ablation strategy that involves pulmonary vein isolation and/or a particular set lines may not be equally effective or efficient in all patients with AF. A tailored targets initiators drivers AF possible alternative to standardized lesion set. Methods Results— Catheter was performed 153 consecutive (mean age, 56±11 years) symptomatic paroxysmal use 8-mm tip radiofrequency catheter. The esophagus...
Pulmonary Vein Tachycardia. Introduction: The significance of intermittent tachycardia within a pulmonary vein (PV) during an episode atrial fibrillation (AF) is unclear. aim this study was to determine the role that PV tachycardias play in AF. Methods and Results: In 56 patients with AF, segmental ostial ablation guided by potentials performed isolate PVs. characteristics inducibility AF before after isolation were analyzed prospectively. During (mean cycle length 130 ± 30 msec) exit block...