A5000525327- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Valve Diseases and Treatments
- ECG Monitoring and Analysis
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Neurological disorders and treatments
- Obstructive Sleep Apnea Research
- Cardiac Imaging and Diagnostics
- Nuclear Structure and Function
- Cardiac Structural Anomalies and Repair
- Venous Thromboembolism Diagnosis and Management
- Heart Failure Treatment and Management
- Pectus Deformity Diagnosis and Treatment
- Poisoning and overdose treatments
- Cardiovascular Syncope and Autonomic Disorders
- Takotsubo Cardiomyopathy and Associated Phenomena
- Dermatological diseases and infestations
- Force Microscopy Techniques and Applications
- Neuroscience and Neural Engineering
- Cardiac tumors and thrombi
- Trauma Management and Diagnosis
Hirslanden Klinik Im Park
2005-2023
Herzgefäss Medizin Klinik Im Park
2009-2022
Center for Pediatric Endocrinology Zurich
2010-2022
University Hospital of Zurich
2000-2019
Universitätsmedizin Greifswald
2019
Klinik Hirslanden
2018
Hospital Universitário Evangélico de Curitiba
2017
Nagoya Heart Center
2013
University of Chicago
2013
Karolinska University Hospital
2013
Background — The pulmonary veins (PVs) have been demonstrated to often play an important role in generating atrial fibrillation (AF). purpose of this study was determine the safety and efficacy segmental PV isolation patients with paroxysmal or persistent AF. Methods Results In 70 consecutive (mean age, 53±11 years) (58) (12) AF, guided by ostial potentials performed. left superior, inferior, right superior PVs were targeted for all patients, inferior isolated 20 patients. Among 230 PVs, 217...
Segmental ostial catheter ablation (SOCA) to isolate the pulmonary veins (PVs) and left atrial (LACA) encircle PVs both may eliminate paroxysmal fibrillation (PAF). The relative efficacy of these 2 techniques has not been directly compared.Of 80 consecutive patients with symptomatic PAF (age, 52+/-10 years), 40 underwent PV isolation by SOCA LACA PVs. During SOCA, potentials recorded a ring were targeted. was performed encircling left- right-sided 1 cm from ostia guided an electroanatomic...
Significant brady- and tachyarrhythmias may occur in active endurance athletes. It is controversial whether these arrhythmias do persist after cessation of competitive training. Among all 134 former Swiss professional cyclists [hereafter, athletes (FAs)] participating at least once the bicycle race Tour de Suisse 1955–1975, 62 (46%) were recruited for study. The control group consisted male golfers matched age, weight, hypertension, cardiac medication. All participants screened with history,...
Background— The purpose of this study was to determine the feasibility and mechanistic implications segmental pulmonary vein (PV) ostial ablation during atrial fibrillation (AF). Methods Results— Forty consecutive patients underwent PV isolation for AF. Among 125 PVs targeted isolation, performed AF in 70 veins sinus rhythm 55 veins. A decapolar Lasso catheter positioned near ostium. During AF, electrodes that recorded a tachycardia with cycle length shorter than adjacent left atrium....
Pulmonary Vein Anatomy. Introduction: The anatomic arrangement of pulmonary veins (PVs) is variable. No prior studies have quantitatively analyzed the effects segmental ostial ablation on PVs. aim this study was to determine effect radiofrequency PV anatomy in patients with atrial fibrillation (AF). Methods and Results: Three‐dimensional models PVs were constructed from computed tomographic (CT) scans 58 AF undergoing isolate 10 control subjects without a history AF. CT repeated...
Pulmonary Vein Tachycardia. Introduction: The significance of intermittent tachycardia within a pulmonary vein (PV) during an episode atrial fibrillation (AF) is unclear. aim this study was to determine the role that PV tachycardias play in AF. Methods and Results: In 56 patients with AF, segmental ostial ablation guided by potentials performed isolate PVs. characteristics inducibility AF before after isolation were analyzed prospectively. During (mean cycle length 130 ± 30 msec) exit block...
BACKGROUND. Spatial resolution in cardiac activation maps based on voltage measurement is limited by far-field interference. Precise characterization of electrical sources would resolve this limitation; however, practical charge-based mapping has not been achieved.
Background: During cardiac resynchronization therapy (CRT), performance is dependent on an optimized atrioventricular delay (AVD). However, the optimal AVD at different heart rates has not been defined yet during CRT. Method: The effects of increase in rate by pacing or physical exercise were studied 36 patients with biventricular pacemakers/defibrillators. velocity time integral (VTI) left ventricular outflow tract (LVOT) was measured pulsed Doppler either three paced supine position seated...
Left atrial catheter ablation of the pulmonary veins (PVs) is an established option for patients with fibrillation (AF). Asymptomatic cerebral emboli (ACE) detected by diffusion weighted MRI (DW-MRI) following AF has been reported at varying rates. This variability may be linked to procedural variables and demographic risk factors. Animal studies multielectrode vein (PVAC) have identified potential sources emboli, including air introduced during PVAC introduction, inadequate anticoagulation,...
In patients with pectus excavatum (PEX), echocardiographic assessment can be difficult. There are little data on the impact of chest deformity findings and comparison obtained by echocardiography (echo) cardiac magnetic resonance imaging (CMR) in PEX. a prospective study, anomalies PEX were analysed echo compared CMR consecutive referred for echo. If they agreed to participate, included if index was ≥3.0 CMR. Also, clinical electrocardiogram tracings analysed. 18 (13 females; 72%), mean age...
Introduction: Bursts of tachycardia arising in the pulmonary veins may play an important role perpetuating atrial fibrillation (AF). However, coronary sinus (CS) perpetuation AF has been unclear. The aim this study was to determine whether CS plays a AF. Methods and Results: Pulmonary vein isolation performed by segmental ostial ablation with radiofrequency energy 22 consecutive patients paroxysmal Bipolar unipolar electrograms recorded left atrium were analyzed during pacing from mitral...
Leadless pacemakers are implanted in Switzerland since June 2015. Large worldwide registries have shown high implant success, low complication rates, and good electrical parameters up to 12 months' follow-up. However, data scarce outside the investigational setting. The purpose of this study is assess real-world experience regarding clinical safety efficacy Micra TPS (transcatheter pacing system) leadless pacemakers. Retrospective observational, multi-centre designed initial Swiss Romande...
Introduction: Based on the clinical history, paroxysmal atrial fibrillation (PAF) may be classified as vagotonic, adrenergic, or random. It is unclear whether pulmonary vein (PV) isolation equally effective for these types of PAF. Methods and Results: Segmental ostial ablation to isolate PVs was performed in 188 consecutive patients (mean age 53 ± 12 years) with PAF random 136 (72%), adrenergic 30 (16%), vagotonic 22 (12%). Three four were targeted all patients, successful achieved 96% PVs....
Circular irrigated radiofrequency ablation using the nMARQ catheter has recently been introduced for treatment of atrial fibrillation (AF). The aim this study is to report safety and efficacy technology in patients with paroxysmal persistent AF.The data a prospective registry describing experience single operator on 327 consecutive were analysed. mean procedure time was 69 ± 22 min AF (n = 228) 75 23 97). Follow-up available 206 (63%) 6 5 months (range 1-23, median 3.3). Single success off...
Introduction: Acutely, when left atrial ablation is performed during fibrillation (AF), the AF may persist and require cardioversion, or it convert to sinus rhythm tachycardia/flutter. The prevalence of these acute outcomes has not been described. Methods Results: Left ablation, usually including encirclement pulmonary veins, was in 144 patients with drug‐refractory AF. Conversion occurred 19 (13%), tachycardia 6 (4%), flutter (4%). In a focal tachycardia, mean cycle length 294 ± 45 ms....
Objective Ibutilide, a class III antiarrhythmic drug, has been shown to convert atrial fibrillation sinus rhythm more rapidly than procainamide or sotalol. Our objective was compare the efficacy and safety of ibutilide amiodarone in patients after cardiac surgery. Design Prospective, randomized, double-blinded study. Setting Intensive care unit university hospital. Patients Forty adults with an onset within 3 hrs admission. Interventions Before administration drugs, 24-hr Holter...
The GOLD AF Registry has been designed to prospectively assess the population, indications, and outcomes using second-generation phased radiofrequency (RF) ablation (pulmonary vein catheter GOLD) in a global examination of standard-of-care use for treatment paroxysmal persistent atrial fibrillation (AF).GOLD (NCT02433613) is prospective, observational, multi-centre registry characterize efficacy safety RF patients with AF. primary endpoint was freedom from recurrence at 12-month follow-up...
Background— Minute ventilation sensors of cardiac pacemakers measure by means transthoracic impedance changes between the pacemaker case and electrode tip. We investigated whether this technique might detect sleep-related breathing disorders. Methods Results— In 22 patients, analog waveforms signal measured minute sensor over course a night were visualized, scored for apnea/hypopnea events, compared with simultaneous polysomnography. Analysis signals correctly identified presence or absence...
AimsDuty-cycled radiofrequency ablation (RFA) has been used for atrial fibrillation (AF) around 5 years, but large-scale data are scarce. The purpose of this survey was to report the outcome technique.