Carina Hardy

ORCID: 0000-0003-3003-3017
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About
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Research Areas
  • Cardiac Arrhythmias and Treatments
  • Atrial Fibrillation Management and Outcomes
  • Cardiac pacing and defibrillation studies
  • Cardiac electrophysiology and arrhythmias
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Syncope and Autonomic Disorders
  • Cardiac Imaging and Diagnostics
  • Heart Rate Variability and Autonomic Control
  • Cardiac tumors and thrombi
  • Cardiovascular Effects of Exercise
  • Cardiovascular Function and Risk Factors
  • Venous Thromboembolism Diagnosis and Management
  • Congenital Heart Disease Studies
  • Trypanosoma species research and implications
  • Cardiac Structural Anomalies and Repair
  • Coronary Artery Anomalies
  • Electrostatic Discharge in Electronics
  • Thyroid and Parathyroid Surgery
  • ECG Monitoring and Analysis
  • Acute Myocardial Infarction Research
  • Systemic Lupus Erythematosus Research
  • Family and Patient Care in Intensive Care Units
  • Cardiovascular and Diving-Related Complications
  • Nuclear Structure and Function
  • Vascular Anomalies and Treatments

Universidade de São Paulo
2015-2025

Instituto do Coração
2020-2025

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2010-2025

Universidade Brasil
2025

Hospital do Coração
2020-2024

Hospital Alemão Oswaldo Cruz
2024

Denso (United States)
2022

Hospital Samaritano de São Paulo
2021

National Heart Institute
2021

Hospital TotalCor
2015

Abstract In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing most common cardiac arrhythmia. 2007, first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence technological advances have resulted a rapidly changing landscape field ablation, thus stressing need regularly updated versions this partnership which were...

10.1093/europace/euae043 article EN cc-by-nc-nd EP Europace 2024-03-30

Background— The aim of this study was to evaluate whether selective radiofrequency (RF) catheter ablation the atrial sites in which high-frequency stimulation induces vagal reflexes prevents paroxysmal fibrillation (AF). Methods and Results— Ten patients with episodes suggestive vagal-induced AF no heart disease were selected for percutaneous epicardial endocardial mapping atria search transcatheter (20 Hz,) induced reflexes. A response defined as AV block >2 seconds elicited 7 10 (70%)...

10.1161/circulationaha.106.633560 article EN Circulation 2006-08-22

Autonomic denervation is an alternative approach for patients with symptomatic bradycardia. No consensus exists on the critical targets and end points of procedure. The aim this study was to identify immediate atrial regions responsible vagal denervation.We enrolled 14 (50% men; age: 34.0±13.8 years) cardioinhibitory syncope, advanced atrioventricular block or sinus arrest, no structural heart disease. Anatomic mapping ganglionated plexuses performed, followed by radiofrequency ablation....

10.1161/circep.116.004638 article EN Circulation Arrhythmia and Electrophysiology 2017-02-01

Background— Epicardial mapping and ablation of accessory pathways through a subxiphoid approach can be an alternative when endocardial or epicardial transvenous has failed. Methods Results— We reviewed acute long-term follow-up 21 patients (14 males) referred for percutaneous pathway ablation. There was median 2 previous failed procedures. All were highly symptomatic, 8 had atrial fibrillation (3 with cardiac arrest) 13 frequent symptomatic episodes atrioventricular reentrant tachycardia....

10.1161/circep.114.002373 article EN Circulation Arrhythmia and Electrophysiology 2014-12-22

Asymptomatic nocturnal long ventricular pauses are usually detected accidentally and it has been suggested that they may lead to sudden death. Identification of predisposing factors could prevent cardiovascular events. We report the case a patient with frequent asymptomatic 3–11 s, characteristic vagally mediated atrioventricular (AV) block. Echocardiography, treadmill test, thyroid function test levels, polysomnogram were normal. In an attempt reduce risk, was decided atrial vagal...

10.1093/europace/euv142 article EN EP Europace 2015-06-11

Cardioneural ablation is a novel treatment for functional bradycardia. However, the risk of acute complications still unknown. The aim this case report to describe occlusion sinus node artery after cardiac denervation procedures in 2 patients and encourage measures prevent it, such as evaluating aortic angulation older before procedure by monitoring signs failure during with electroanatomical maps showing constricted aspect right atrium. (Level Difficulty: Advanced.).

10.1016/j.jaccas.2022.04.021 article EN cc-by-nc-nd JACC Case Reports 2022-09-01

Resumo Fundamento A ocorrência de fístula atrioesofágica após o procedimento ode ablação fibrilação atrial (FA) continua uma preocupação. Não existe abordagem padronizada para minimizar seus riscos e mortalidade. Objetivos Apresentar a experiência sete anos um monitoramento endoscópico sistemático lesão esofágica FA por cateter. Métodos Estudo unicêntrico retrospectivo avaliação endoscópica sistemática em procedimentos consecutivos realizados entre 2016 2022. Um valor p < 0.05 foi...

10.36660/abc.20230913 article PT cc-by Arquivos Brasileiros de Cardiologia 2025-03-01

Abstract Background Atrial-esophageal fistula following AF ablation remains a concern. There is no standardized approach to minimize its risk and morbidity. Objective To present the seven-year experience of systematic endoscopic surveillance esophageal injury after catheter ablation. Methods This retrospective single center registry evaluation in consecutive procedures performed from 2016 2022. A p-value <0.05 was considered statistically significant. Results 823 with controlled...

10.36660/abc.20230913i article EN cc-by Arquivos Brasileiros de Cardiologia 2025-03-01

Puncture of the atrial appendage may provide access to pericardial space. The aim this study was evaluate feasibility epicardial mapping and ablation through an endocardial transatrial in a swine model.An 8-F Mullins sheath used perforate right (n=16) or left (n=1) 17 pigs (median weight, 27.5 kg; first third quartiles [Q1, Q3], 25.2, 30.0 kg). A 7-F catheter introduced into space perform deliver radiofrequency pulses on atria. entered all animals. In 15 (88%) animals, there no hemodynamic...

10.1161/circep.110.960799 article EN Circulation Arrhythmia and Electrophysiology 2011-03-24

Background— The proximity to vascular structures is a limiting factor during radiofrequency ablation. However, little or no attention has been given the atrial arterial circulation development of fibrillation (AF) catheter ablation techniques. Methods and Results— We examined in areas involved AF 24 heart specimens by colored resin injection careful dissection. sinus node artery (SNA) arose from circumflex 42% case; proximal LA appendage 29%, crossing left atrium (LA) anterior wall; after...

10.1161/circep.110.951525 article EN Circulation Arrhythmia and Electrophysiology 2010-09-19

Torsades de pointes (TdP) ventricular tachycardias carry a high risk of sudden death, even when they occur in individuals with structurally normal heart, the absence myocardial ischemia or prolonged QT interval. Leenhardt et al1 described new syndrome these characteristics 1994 that showed difference which TdP were triggered by extrasystoles (VE) ultra-short coupling interval (< 300 ms). Although this condition is easily diagnosed characteristics, there lack data on clinical management...

10.5935/abc.20140075 article EN cc-by-nc Arquivos Brasileiros de Cardiologia 2014-01-01

Abstract Objective To compare the prevalence of esophageal and periesophageal thermal injury in patients undergoing radiofrequency (RF) atrial fibrillation (AF) ablation using 8 mm tip catheters during three different protection strategies. Methods Forty‐five consecutive with paroxysmal or persistent AF underwent first procedure, besides esophagogastroduodenoscopy (EGD) combined radial endosonography (EUS) performed before after pulmonary vein (PV) isolation. Before were randomly assigned to...

10.1111/jce.14417 article EN Journal of Cardiovascular Electrophysiology 2020-02-28

Arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disease, causes tachycardia, sudden cardiac death, and heart failure (HF). We investigated ARVC clinical features, genetic findings, natural history, the occurrence of life-threatening arrhythmic events (LTAEs), HF or transplantation (HF-death/HTx) to identify risk factors.The course 111 consecutive patients with definite ARVC, predictors LTAE, HF-death/HTx, combined were analyzed in entire cohort subgroup 40 without...

10.1161/circep.122.011391 article EN Circulation Arrhythmia and Electrophysiology 2023-01-31

To verify whether spectral components of atrial electrograms (AE) during sinus rhythm (SR) correlate with cardiac ganglionated plexus (GP) sites.Thirteen patients undergoing fibrillation (AF) ablation were prospectively enrolled. Prior to radio frequency application, endocardial AE recorded a sequential point-by-point approach. Electrical stimuli delivered at 20 Hz, amplitude 100 V, and pulse width 4 ms. A vagal response was defined as high-frequency stimulation (HFS) evoked atrioventricular...

10.1093/europace/eur074 article EN EP Europace 2011-03-31
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