- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Virus-based gene therapy research
- Animal Disease Management and Epidemiology
- Acute Ischemic Stroke Management
- Viral Infections and Immunology Research
- Emergency and Acute Care Studies
- Venous Thromboembolism Diagnosis and Management
- Rabies epidemiology and control
- Healthcare Policy and Management
- Vector-Borne Animal Diseases
- Patient Satisfaction in Healthcare
- Customer Service Quality and Loyalty
- Venomous Animal Envenomation and Studies
- Systemic Lupus Erythematosus Research
- Streptococcal Infections and Treatments
- Diabetes Treatment and Management
- Atherosclerosis and Cardiovascular Diseases
- Intracranial Aneurysms: Treatment and Complications
- Peripheral Neuropathies and Disorders
- Chronic Disease Management Strategies
- Virology and Viral Diseases
- Herpesvirus Infections and Treatments
- Bacteriophages and microbial interactions
- Stroke Rehabilitation and Recovery
Hungkuang University
2012-2024
Taichung Veterans General Hospital
2010-2024
National Yang Ming Chiao Tung University
2012-2023
National Chung Hsing University
2012-2023
McGill University Health Centre
2020
China Medical University
2010-2019
Australian Centre for Disease Preparedness
2014
Commonwealth Scientific and Industrial Research Organisation
2014
Uniformed Services University of the Health Sciences
2014
Zoetis (United States)
2014
Abstract In recent years, the emergence of several highly pathogenic zoonotic diseases in humans has led to a renewed emphasis on interconnectedness human, animal, and environmental health, otherwise known as One Health. For example, Hendra virus (HeV), paramyxovirus, was discovered 1994, since then, infections have occurred 7 humans, each whom had strong epidemiologic link similarly affected horses. As consequence these outbreaks, eradication bat populations discussed, despite their crucial...
Abstract Background Limited evidence exists to support any specific medication over others prevent dementia in older patients with type 2 diabetes (T2D). We investigated whether treatment sodium‐glucose cotransporter (SGLT‐2) inhibitors is associated a lower risk of incident and all‐cause mortality, relative dipeptidyl peptidase‐4 (DPP‐4) glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA). Methods In this retrospective, active‐comparator cohort study, we used data from the TriNetX...
Objective Shewanella bacteremia is an uncommon but potentially fatal disease. Although hepatobiliary diseases have been proposed to be risk factors for various infections, little known about the features of in patients with diseases. This study aims characterize presentation and Methods We retrospectively investigated clinical features, microbiology outcomes who were admitted a tertiary medical center between January 2001 December 2010. All isolates confirmed species level using 16S rRNA...
Percutaneous drainage (PCD) and surgical intervention are two primary treatment options for iliopsoas abscess (IPA). However, there is currently no consensus on when to use PCD or intervention, especially in patients with gas-forming IPA. This study compared the characteristics of non-gas forming IPA their mortality rates under different modalities. An algorithm selecting appropriate proposed based our findings.Eighty-eight between July 2007 February 2013 were enrolled this retrospective...
There are very few microbiological data on wound infections following snakebites. The objective of this study was to investigate the treatment secondary infection snakebites in central Taiwan. Microbiological and antibiotic sensitivity cultures were retrospectively analyzed from December 2005 October 2007 a medical center A total 121 snakebite patients participated study. Forty-nine (40.5%) subjects bitten by cobra (Naja atra); 34 them had infection, 24 (70.6%) needed surgical intervention....
To determine whether client-owned dogs in Australia, last vaccinated with Canvac(®) vaccines containing canine parvovirus-type 2 (CPV-2), distemper virus (CDV), adenovirus type (CAV-2) ± parainfluenza (CPiV) at least 18 months ago, were seropositive or responded serologically to revaccination.A total of 235 recruited from 23 veterinary clinics, representing a variety breeds, ages and time since vaccination (TSLV: range 1.5-9 years, mean 2.8 years). Dogs had blood sample taken revaccinated on...
The medical industry faces rapid changes and more competitive environment in recent years, so innovation has become the key element to improve advantage for hospitals. We investigated determinants of technological its influence on hospital performance through samples Taiwan. conducted a cross-sectional study data were obtained from four secondary databases: “Taiwan Hospital Annual”, “Statistical Yearbook Interior” Taiwan Association, “registry contracted facilities” beds” National Health...
Abstract Diabetes mellitus is a risk factor for Parkinson's disease (PD). While animal studies have supported the benefits of incretin-based therapies, including dipeptidyl peptidase-4 (DPP4) inhibitors, in PD, clinical research has yielded controversial results. This cohort study aimed to assess relationship between PD incidence and utilization DPP4 inhibitor diabetic patients. Using Taiwan's National Health Insurance Research Database from 2009 2018, patients receiving metformin plus at...
OBJECTIVE: Infections of snake bite wounds by Shewanella are rarely discussed in the medical literature.This study aims to characterize presentation and management infections wounds. METHOD:We retrospectively investigated microbiology, clinical features, outcomes patients with infected admitted a tertiary center from January 1998 December 2009. RESULTS:Ten Shewanella-infected were identified.All bites caused cobras.The majority had moderate severe local envenomation polymicrobial...
Poststroke epilepsy (PSE) is a common complication after ischemic stroke. This study investigates the association between use of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) and risk PSE in patients with
Equine rhinovirus serotype 3 isolate P313/75 was assigned, with an unclassified genus status, to the family Picornaviridae . The sequence from 5′ poly(C) tract 3′ poly(A) of determined. is 8821 bases in length and contains a potential open reading frame for polyprotein 2583 amino acids. Sequence comparison phylogenic analysis suggest that most closely related prototype equine rhinitis B virus (ERBV) strain P1436/71, formerly named type 2. A high degree similarity found P2 P3 regions two...
Fecal specimens from 78 calves involved in outbreaks of calf diarrhea which occurred three farms Victoria, Australia, 1988 were analyzed for rotaviruses. Thirty-eight samples positive group A virus antigen by enzyme-linked immunosorbent assay, and 20 these contained viral double-stranded RNAs that could be detected polyacrylamide gel electrophoresis. Two major electropherotypes observed, a representative isolate each electropherotype (isolates B-11 B-60) was successfully adapted to grow...
Elderly persons are thought to use emergency departments (EDs) disproportionately. This phenomenon has implications for policy‐making as the population of elderly continues increase. study aimed characterize national ED utilization by patients (≥ 65 years old), compared with that younger (15‐64 old). The sample was selected from National Health Insurance Research Database year 2000. There were 519,003 visits adult EDs in 12 medical centers sampled. used a secondary data analysis and included...
Aims and objectives. To explore the cross‐level effects of four dimensions patient safety climate on nursing innovation. Background. Across globe, innovation is highly encouraged by experts to improve outcome. Nursing innovation, in turn, affected organisational climate, a critical aspect safety. Design. This cross‐sectional study. Methods. We employed questionnaire survey collect data selected nurses from Taiwan hospitals as samples. A total 808 valid questionnaires 172 teams were...
Equine rhinitis A virus (ERAV) is a member of the genus Aphthovirus, family Picornaviridae, and causes respiratory disease in horses worldwide. To characterize putative receptor molecule(s) ERAV isolate 393/76 (ERAV.393/76) on surface Vero other cells, an assay was developed to measure binding purified biotinylated ERAV.393/76 virions cells by flow cytometry. Using this assay, level different cell types correlated with relative infectivity each type. In particular, equine fetal kidney mouse...
Adrenoleukodystrophy (ALD) is a rare and progressive neurogenetic disease that may manifest disparate symptoms. The present study aims at investigating the role of ataxic variant ALD (AVALD) in patients with adult-onset cerebellar ataxia, as well characterizing their clinical features distinguish AVALD from other ataxias. Mutations ATP binding cassette subfamily D member 1 gene (ABCD1) were ascertained 516 unrelated ataxia. categorized into three groups: molecularly unassigned hereditary...
Equine rhinitis A virus (ERAV) is a picornavirus that has been reclassified as member of the Aphthovirus genus because its resemblance to foot-and-mouth disease at level nucleotide sequence and overall genomic structure. The N-terminal amino acid three four capsid proteins ERAV was determined showed proteolytic cleavage sites within precursor P1 polypeptide occur exactly those predicted for an aphthovirus-like 3C protease, which generates VP1 VP3. However, autocatalytic site between VP4 VP2,...