A5046509454- Occupational exposure and asthma
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Astronomy and Astrophysical Research
- Galaxies: Formation, Evolution, Phenomena
- Inhalation and Respiratory Drug Delivery
- Occupational and environmental lung diseases
- Contact Dermatitis and Allergies
- Gamma-ray bursts and supernovae
- Stellar, planetary, and galactic studies
- Astrophysics and Star Formation Studies
- Indoor Air Quality and Microbial Exposure
- Astro and Planetary Science
- Computational Physics and Python Applications
- Pediatric health and respiratory diseases
- Astronomical Observations and Instrumentation
- Air Quality and Health Impacts
- Astrophysical Phenomena and Observations
- Planetary Science and Exploration
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Dermatology and Skin Diseases
- Food Allergy and Anaphylaxis Research
- Respiratory and Cough-Related Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Analytical Methods in Pharmaceuticals
The University of Texas at Austin
2023-2024
University of Wisconsin–Madison
2020-2023
Imperial College London
1998-2019
Center for Astrophysics Harvard & Smithsonian
2018
GlaxoSmithKline (United Kingdom)
2014-2016
Royal Brompton Hospital
1985-2009
University of Nottingham
1978-2007
Queen's Medical Centre
2007
Lung Institute
1989-2003
National Institutes of Health
1995-2001
Abstract We present a sample of 88 candidate z ∼ 8.5–14.5 galaxies selected from the completed NIRCam imaging Cosmic Evolution Early Release Science survey. These data cover ∼90 arcmin 2 (10 pointings) in six broadband filters and one medium-band filter. With this we confirm at higher confidence early JWST conclusions that bright epoch are more abundant than predicted by most theoretical models. construct rest-frame ultraviolet luminosity functions 9, 11, 14 show space density ( M UV = −20)...
Abstract We analyze the evolution of massive (log 10 [ M ⋆ / ⊙ ] > 10) galaxies at z ∼ 1–4 selected from JWST Cosmic Evolution Early Release Survey (CEERS). infer physical properties all in CEERS NIRCam imaging through spectral energy distribution (SED) fitting with dense basis to select a sample high-redshift galaxies. Where available we include constraints additional observing modes, including 18 sources MIRI photometric coverage, and 28 spectroscopic confirmations NIRSpec or WFSS....
Abstract JWST’s Early Release Observations of the lensing cluster SMACS J0723.3–7327 have given an unprecedented spectroscopic look into high-redshift universe. These observations reveal five galaxies at z > 5. All detectable [O iii ] λ 4363 line emission, indicating that these high temperatures and low metallicities they are highly star-forming. In recent work, been studied using various techniques. Here we summarize compare previous results, as well perform our own measurements improved...
Abstract Deep Very Large Telescope/MUSE optical integral field spectroscopy has recently revealed an abundant population of ultra-faint galaxies ( M UV ≈ −15; 0.01 L ⋆ ) at z = 2.9−6.7 due to their strong Ly α emission with no detectable continuum. The implied equivalent widths can be in excess 100–200 Å, challenging existing models normal star formation and indicating extremely young ages, small stellar masses, a very low amount metal enrichment. We use JWST/NIRSpec’s microshutter array...
Several studies have investigated water/salt soluble proteins which comprise 50% of the in wheat. The remaining wheat proteins, are insoluble there is limited information on their role cereal hypersensitivity.To investigate allergenicity gliadin and glutenin (prolamins).RAST, electrophoresis Western blotting were used to identify allergens. Competitive RAST inhibition was conducted cross-reactivity between prolamins proteins.Specific IgE alpha-gliadin total glutenins detected all sera....
Journal Article Environmental associations with eczema in early life Get access J.M. Harris, Harris Department of Occupational and Medicine, Imperial College Science Technology (National Heart Lung Institute), 1b Manresa Road, London SW3 6LR, U.K. *Department Dermatology, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH, J.M.Harris. E‐mail: jessica.harris@ic.ac.uk Search for other works by this author on: Oxford Academic Google Scholar P. Cullinan, Cullinan H.C. Williams,...
Although it is widely assumed that the incidence of childhood respiratory allergies to common aeroallergens directly related allergen exposure in early life, few longitudinal studies have investigated this issue, and available data are scarce mainly limited high-risk groups.To assess, a prospective manner general population, role life exposures Der p1 Fel d1 on inception sensitization asthma.Pregnant women their children were recruited for Asthma Multicentre Infant Cohort Study. Overall,...
Summary Six workers with a diagnosis of occupational asthma and one chronic bronchitis were examined for sensitivity to epoxy resin systems certain their components. In six cases the chemical agent responsible symptoms was identified by careful inhalation challenge testing, simulating exposure at work thus providing precise aetiological diagnosis. worker followed triethylene tetramine fume; four sensitive acid anhydrides, three phthalic anhydride as fume or powder trimellitic anhydride. One...
We present a sample of 341 "little red dots" (LRDs) spanning the redshift range $z\sim2-11$ using data from CEERS, PRIMER, JADES, UNCOVER and NGDEEP surveys. These sources are likely heavily-reddened AGN that trace previously-hidden phase dust-obscured black hole growth in early Universe. Unlike past use color indices to identify LRDs, we employ continuum slope fitting shifting bandpasses same rest-frame emission blueward redward Balmer break. This approach allows us LRDs over wider is less...
BACKGROUND: There is a need for new respiratory symptoms questionnaire use in epidemiological research asthma. METHOD: A was designed following pilot study 78 subjects. It contains nine questions on such as wheeze and difficulty with breathing defined circumstances exercise sleep. completed by 211 adults validated comparison self reported history of asthma bronchial hyperresponsiveness to histamine. Its short term reproducibility measured three repeat administrations over two weeks. RESULTS:...
To describe the levels of exposure to fungal alpha-amylase in British bakeries and flour mills, relation between sensitisation alpha-amylase.495 personal dust samples were taken seven mills analysed for with an immunoassay. Workers at sites asked fill out questionnaires on work related symptoms, smoking history, they skin prick tested common allergens assess sensitisation.Exposure high concentrations occur a few areas there can be considerable differences exposures groups, even within...
The relationship between exposure to indoor aeroallergens in early life and subsequent eczema is unclear. We have previously failed show any significant associations house dust mite cat fur allergens either sensitization these or wheeze. also reported a lower prevalence of parent-reported, doctor-diagnosed by age 2 years for children exposed higher concentrations mite, but no other with definitions allergen.To extend the exposure-response analysis allergen outcomes measured up 8 years,...
We present a sample of 88 candidate z~8.5-14.5 galaxies selected from the completed NIRCam imaging Cosmic Evolution Early Release Science (CEERS) survey. These data cover ~90 arcmin^2 (10 pointings) in six broad-band and one medium-band filter. With this we confirm at higher confidence early JWST conclusions that bright epoch are more abundant than predicted by most theoretical models. construct rest-frame ultraviolet luminosity functions z~9, 11 14, show space density (M_UV=-20) changes...
Background Urban‐rural differences in the prevalence of atopy and associated allergic diseases have been reported several non‐European countries. Within Europe, where such variations are less striking, a farm childhood has postulated to be protective. Objective We aimed compare urban rural children living Crete examine role early exposure farming environment explaining any measured differences. Methods A cross‐sectional survey attending secondary schools Iraklion, capital city, five villages...
To investigate the role of cereal alpha and beta-amylase in bakers' asthma, we have compared IgE response 30 wheat-flour-allergic individuals to barley beta-amylases with that fungal alpha-amylase using radioallergosorbent test (RAST), RAST inhibition assays Western blotting. analysis showed 29 subjects inhalant induced allergy had positive amylases, but only 16 were alpha-amylase. Regression an association between specific wheat-flour (r = 0.70) 0.92) a poor 0.34). minimal crossreactivity...
Abstract We present the results of a Keck and Northern Extended Millimeter Array spectroscopic survey 507 galaxies, where we confirm presence two massive overdensities at z = 3.090−3.110 3.133−3.155 in neighborhood GOODS-N, each with over dozen spectroscopically confirmed members. find that both these have galaxy near-infrared-detected galaxies δ gal,obs 6−9 within corrected volumes (6−7) × 10 3 cMpc . estimate properties 0 descendants using spherical collapse model should virialize by ≃...
Abstract JWST has now revealed a population of broad-line active galactic nuclei (AGN) at z ≳ 4 characterized by distinctive spectral energy distribution shape, with very red rest-frame optical and blue UV continuum. While the continuum is thought to originate from accretion disk, origin been largely unclear. We report detection strong emission lines C iii ] λλ 1907, 1909 iv 1549, 1551 in “little dot” AGN, COS-66964. Spectroscopically confirmed = 7.0371, COS-66964 exhibits broad H α (FWHM ∼...
Abstract We present the Cosmic Evolution Early Release Science (CEERS) Survey, a 77.2 hr Director’s Discretionary Program. CEERS demonstrates, tests, and validates efficient extragalactic surveys using coordinated, overlapping parallel observations with JWST instrument suite, including NIRCam MIRI imaging, NIRSpec low- ( R ∼ 100) medium- 1000) resolution spectroscopy, slitless grism 1500) spectroscopy. targets Hubble Space Telescope–observed region of Extended Groth Strip field, supported by...